193 related articles for article (PubMed ID: 28416445)
1. αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype.
Zhangsun D; Zhu X; Kaas Q; Wu Y; Craik DJ; McIntosh JM; Luo S
Neuropharmacology; 2017 Dec; 127():243-252. PubMed ID: 28416445
[TBL] [Abstract][Full Text] [Related]
2. Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist.
Luo S; Zhangsun D; Harvey PJ; Kaas Q; Wu Y; Zhu X; Hu Y; Li X; Tsetlin VI; Christensen S; Romero HK; McIntyre M; Dowell C; Baxter JC; Elmslie KS; Craik DJ; McIntosh JM
Proc Natl Acad Sci U S A; 2015 Jul; 112(30):E4026-35. PubMed ID: 26170295
[TBL] [Abstract][Full Text] [Related]
3. Structure-Activity Relationships of Alanine Scan Mutants αO-Conotoxins GeXIVA[1,2] and GeXIVA[1,4].
Xu P; Zhang P; Zhu X; Wu Y; Harvey PJ; Kaas Q; Zhangsun D; Craik DJ; Luo S
J Med Chem; 2023 Jul; 66(14):10092-10107. PubMed ID: 37464764
[TBL] [Abstract][Full Text] [Related]
4. Structure and Activity Studies of Disulfide-Deficient Analogues of αO-Conotoxin GeXIVA.
Xu P; Kaas Q; Wu Y; Zhu X; Li X; Harvey PJ; Zhangsun D; Craik DJ; Luo S
J Med Chem; 2020 Feb; 63(4):1564-1575. PubMed ID: 31986036
[TBL] [Abstract][Full Text] [Related]
5. Orthosteric and/or Allosteric Binding of α-Conotoxins to Nicotinic Acetylcholine Receptors and Their Models.
Kryukova EV; Ivanov IA; Lebedev DS; Spirova EN; Egorova NS; Zouridakis M; Kasheverov IE; Tzartos SJ; Tsetlin VI
Mar Drugs; 2018 Nov; 16(12):. PubMed ID: 30469507
[TBL] [Abstract][Full Text] [Related]
6. αO-Conotoxin GeXIVA Inhibits the Growth of Breast Cancer Cells via Interaction with α9 Nicotine Acetylcholine Receptors.
Sun Z; Bao J; Zhangsun M; Dong S; Zhangsun D; Luo S
Mar Drugs; 2020 Apr; 18(4):. PubMed ID: 32272701
[TBL] [Abstract][Full Text] [Related]
7. Effects of serum, enzyme, thiol, and forced degradation on the stabilities of αO-Conotoxin GeXIVA[1,2] and GeXIVA [1,4].
Yu S; Wu Y; Xu P; Wang S; Zhangsun D; Luo S
Chem Biol Drug Des; 2018 May; 91(5):1030-1041. PubMed ID: 29316361
[TBL] [Abstract][Full Text] [Related]
8. Globular and ribbon isomers of Conus geographus α-conotoxins antagonize human nicotinic acetylcholine receptors.
Tae HS; Gao B; Jin AH; Alewood PF; Adams DJ
Biochem Pharmacol; 2021 Aug; 190():114638. PubMed ID: 34062129
[TBL] [Abstract][Full Text] [Related]
9. αS-conotoxin GVIIIB potently and selectively blocks α9α10 nicotinic acetylcholine receptors.
Christensen SB; Bandyopadhyay PK; Olivera BM; McIntosh JM
Biochem Pharmacol; 2015 Aug; 96(4):349-56. PubMed ID: 26074268
[TBL] [Abstract][Full Text] [Related]
10. Anti-hypersensitive effect of intramuscular administration of αO-conotoxin GeXIVA[1,2] and GeXIVA[1,4] in rats of neuropathic pain.
Li X; Hu Y; Wu Y; Huang Y; Yu S; Ding Q; Zhangsun D; Luo S
Prog Neuropsychopharmacol Biol Psychiatry; 2016 Apr; 66():112-119. PubMed ID: 26706456
[TBL] [Abstract][Full Text] [Related]
11. Differential Expression of Nicotine Acetylcholine Receptors Associates with Human Breast Cancer and Mediates Antitumor Activity of αO-Conotoxin GeXIVA.
Sun Z; Zhangsun M; Dong S; Liu Y; Qian J; Zhangsun D; Luo S
Mar Drugs; 2020 Jan; 18(1):. PubMed ID: 31963558
[TBL] [Abstract][Full Text] [Related]
12. Medicinal chemistry, pharmacology, and therapeutic potential of α-conotoxins antagonizing the α9α10 nicotinic acetylcholine receptor.
Li X; Tae HS; Chu Y; Jiang T; Adams DJ; Yu R
Pharmacol Ther; 2021 Jun; 222():107792. PubMed ID: 33309557
[TBL] [Abstract][Full Text] [Related]
13. The α9α10 Nicotinic Acetylcholine Receptor Antagonist αO-Conotoxin GeXIVA[1,2] Alleviates and Reverses Chemotherapy-Induced Neuropathic Pain.
Wang H; Li X; Zhangsun D; Yu G; Su R; Luo S
Mar Drugs; 2019 May; 17(5):. PubMed ID: 31060282
[TBL] [Abstract][Full Text] [Related]
14. Scanning mutagenesis of alpha-conotoxin Vc1.1 reveals residues crucial for activity at the alpha9alpha10 nicotinic acetylcholine receptor.
Halai R; Clark RJ; Nevin ST; Jensen JE; Adams DJ; Craik DJ
J Biol Chem; 2009 Jul; 284(30):20275-84. PubMed ID: 19447885
[TBL] [Abstract][Full Text] [Related]
15. Conotoxin Interactions with α9α10-nAChRs: Is the α9α10-Nicotinic Acetylcholine Receptor an Important Therapeutic Target for Pain Management?
Mohammadi SA; Christie MJ
Toxins (Basel); 2015 Sep; 7(10):3916-32. PubMed ID: 26426047
[TBL] [Abstract][Full Text] [Related]
16. A novel α4/7-conotoxin LvIA from Conus lividus that selectively blocks α3β2 vs. α6/α3β2β3 nicotinic acetylcholine receptors.
Luo S; Zhangsun D; Schroeder CI; Zhu X; Hu Y; Wu Y; Weltzin MM; Eberhard S; Kaas Q; Craik DJ; McIntosh JM; Whiteaker P
FASEB J; 2014 Apr; 28(4):1842-53. PubMed ID: 24398291
[TBL] [Abstract][Full Text] [Related]
17. α-Conotoxin Vc1.1 Structure-Activity Relationship at the Human α9α10 Nicotinic Acetylcholine Receptor Investigated by Minimal Side Chain Replacement.
Chu X; Tae HS; Xu Q; Jiang T; Adams DJ; Yu R
ACS Chem Neurosci; 2019 Oct; 10(10):4328-4336. PubMed ID: 31411453
[TBL] [Abstract][Full Text] [Related]
18. Molecular basis for the differential sensitivity of rat and human α9α10 nAChRs to α-conotoxin RgIA.
Azam L; McIntosh JM
J Neurochem; 2012 Sep; 122(6):1137-44. PubMed ID: 22774872
[TBL] [Abstract][Full Text] [Related]
19. Discovery and Structural and Functional Characterization of a Novel A-Superfamily Conotoxin Targeting α9α10 Nicotinic Acetylcholine Receptor.
Huang Q; Chu X; Zhang H; Yu S; Zhang L; Zhang X; Yu R; Guo C; Dai Q
ACS Chem Biol; 2022 Sep; 17(9):2483-2494. PubMed ID: 36048451
[TBL] [Abstract][Full Text] [Related]
20. Critical residue properties for potency and selectivity of α-Conotoxin RgIA towards α9α10 nicotinic acetylcholine receptors.
Huynh PN; Harvey PJ; Gajewiak J; Craik DJ; Michael McIntosh J
Biochem Pharmacol; 2020 Nov; 181():114124. PubMed ID: 32593612
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
