404 related articles for article (PubMed ID: 28416701)
1. Defective synaptic connectivity and axonal neuropathology in a human iPSC-based model of familial Parkinson's disease.
Kouroupi G; Taoufik E; Vlachos IS; Tsioras K; Antoniou N; Papastefanaki F; Chroni-Tzartou D; Wrasidlo W; Bohl D; Stellas D; Politis PK; Vekrellis K; Papadimitriou D; Stefanis L; Bregestovski P; Hatzigeorgiou AG; Masliah E; Matsas R
Proc Natl Acad Sci U S A; 2017 May; 114(18):E3679-E3688. PubMed ID: 28416701
[TBL] [Abstract][Full Text] [Related]
2. Nitration of microtubules blocks axonal mitochondrial transport in a human pluripotent stem cell model of Parkinson's disease.
Stykel MG; Humphries K; Kirby MP; Czaniecki C; Wang T; Ryan T; Bamm V; Ryan SD
FASEB J; 2018 Oct; 32(10):5350-5364. PubMed ID: 29688812
[TBL] [Abstract][Full Text] [Related]
3. Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons.
Zambon F; Cherubini M; Fernandes HJR; Lang C; Ryan BJ; Volpato V; Bengoa-Vergniory N; Vingill S; Attar M; Booth HDE; Haenseler W; Vowles J; Bowden R; Webber C; Cowley SA; Wade-Martins R
Hum Mol Genet; 2019 Jun; 28(12):2001-2013. PubMed ID: 30753527
[TBL] [Abstract][Full Text] [Related]
4. Generation of gene-corrected iPSC line from Parkinson's disease patient iPSC line with alpha-SNCA A53T mutation.
Lee SY; Jeong S; Kim J; Chung SK
Stem Cell Res; 2018 Jul; 30():145-149. PubMed ID: 29906669
[TBL] [Abstract][Full Text] [Related]
5. In Vivo Phenotyping of Familial Parkinson's Disease with Human Induced Pluripotent Stem Cells: A Proof-of-Concept Study.
Zygogianni O; Antoniou N; Kalomoiri M; Kouroupi G; Taoufik E; Matsas R
Neurochem Res; 2019 Jun; 44(6):1475-1493. PubMed ID: 30989481
[TBL] [Abstract][Full Text] [Related]
6. Axonal pathology in hPSC-based models of Parkinson's disease results from loss of Nrf2 transcriptional activity at the Map1b gene locus.
Czaniecki C; Ryan T; Stykel MG; Drolet J; Heide J; Hallam R; Wood S; Coackley C; Sherriff K; Bailey CDC; Ryan SD
Proc Natl Acad Sci U S A; 2019 Jul; 116(28):14280-14289. PubMed ID: 31235589
[TBL] [Abstract][Full Text] [Related]
7. α-Synuclein oligomers induce early axonal dysfunction in human iPSC-based models of synucleinopathies.
Prots I; Grosch J; Brazdis RM; Simmnacher K; Veber V; Havlicek S; Hannappel C; Krach F; Krumbiegel M; Schütz O; Reis A; Wrasidlo W; Galasko DR; Groemer TW; Masliah E; Schlötzer-Schrehardt U; Xiang W; Winkler J; Winner B
Proc Natl Acad Sci U S A; 2018 Jul; 115(30):7813-7818. PubMed ID: 29991596
[TBL] [Abstract][Full Text] [Related]
8. Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons.
Koch JC; Bitow F; Haack J; d'Hedouville Z; Zhang JN; Tönges L; Michel U; Oliveira LM; Jovin TM; Liman J; Tatenhorst L; Bähr M; Lingor P
Cell Death Dis; 2015 Jul; 6(7):e1811. PubMed ID: 26158517
[TBL] [Abstract][Full Text] [Related]
9. Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Familial Parkinson's Disease Patients Display α-Synuclein Pathology and Abnormal Mitochondrial Morphology.
Diao X; Wang F; Becerra-Calixto A; Soto C; Mukherjee A
Cells; 2021 Sep; 10(9):. PubMed ID: 34572052
[TBL] [Abstract][Full Text] [Related]
10. Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity.
Hu D; Sun X; Liao X; Zhang X; Zarabi S; Schimmer A; Hong Y; Ford C; Luo Y; Qi X
Acta Neuropathol; 2019 Jun; 137(6):939-960. PubMed ID: 30877431
[TBL] [Abstract][Full Text] [Related]
11. Early Signs of Molecular Defects in iPSC-Derived Neural Stems Cells from Patients with Familial Parkinson's Disease.
Akrioti E; Karamitros T; Gkaravelas P; Kouroupi G; Matsas R; Taoufik E
Biomolecules; 2022 Jun; 12(7):. PubMed ID: 35883433
[TBL] [Abstract][Full Text] [Related]
12. E46K mutant α-synuclein is more degradation resistant and exhibits greater toxic effects than wild-type α-synuclein in Drosophila models of Parkinson's disease.
Sakai R; Suzuki M; Ueyama M; Takeuchi T; Minakawa EN; Hayakawa H; Baba K; Mochizuki H; Nagai Y
PLoS One; 2019; 14(6):e0218261. PubMed ID: 31242217
[TBL] [Abstract][Full Text] [Related]
13. Differential interaction between iron and mutant alpha-synuclein causes distinctive Parkinsonian phenotypes in Drosophila.
Zhu ZJ; Wu KC; Yung WH; Qian ZM; Ke Y
Biochim Biophys Acta; 2016 Apr; 1862(4):518-525. PubMed ID: 26769358
[TBL] [Abstract][Full Text] [Related]
14. αSynuclein control of mitochondrial homeostasis in human-derived neurons is disrupted by mutations associated with Parkinson's disease.
Pozo Devoto VM; Dimopoulos N; Alloatti M; Pardi MB; Saez TM; Otero MG; Cromberg LE; Marín-Burgin A; Scassa ME; Stokin GB; Schinder AF; Sevlever G; Falzone TL
Sci Rep; 2017 Jul; 7(1):5042. PubMed ID: 28698628
[TBL] [Abstract][Full Text] [Related]
15. Modeling Parkinson's disease with induced pluripotent stem cells harboring α-synuclein mutations.
Singh Dolt K; Hammachi F; Kunath T
Brain Pathol; 2017 Jul; 27(4):545-551. PubMed ID: 28585381
[TBL] [Abstract][Full Text] [Related]
16. The regulatory role of α-synuclein and parkin in neuronal cell apoptosis; possible implications for the pathogenesis of Parkinson's disease.
Yasuda T; Mochizuki H
Apoptosis; 2010 Nov; 15(11):1312-21. PubMed ID: 20221696
[TBL] [Abstract][Full Text] [Related]
17. Modeling Parkinson's Disease Using Patient-specific Induced Pluripotent Stem Cells.
Li H; Jiang H; Zhang B; Feng J
J Parkinsons Dis; 2018; 8(4):479-493. PubMed ID: 30149462
[TBL] [Abstract][Full Text] [Related]
18. Parkinson's disease-linked
Chen X; Kordich JK; Williams ET; Levine N; Cole-Strauss A; Marshall L; Labrie V; Ma J; Lipton JW; Moore DJ
Proc Natl Acad Sci U S A; 2019 Mar; 116(12):5765-5774. PubMed ID: 30842285
[TBL] [Abstract][Full Text] [Related]
19. iPS cells in the study of PD molecular pathogenesis.
Cobb MM; Ravisankar A; Skibinski G; Finkbeiner S
Cell Tissue Res; 2018 Jul; 373(1):61-77. PubMed ID: 29234887
[TBL] [Abstract][Full Text] [Related]
20. Generation of gene-corrected isogenic controls from Parkinson's disease patient iPSC lines carrying the pathogenic SNCA p.A53T variant.
Kozhushko N; Beilina A; Cookson MR
Stem Cell Res; 2023 Jun; 69():103125. PubMed ID: 37229975
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]