BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

551 related articles for article (PubMed ID: 28418202)

  • 1. Benzodioxole-Pyrazole Hybrids as Anti-Inflammatory and Analgesic Agents with COX-1,2/5-LOX Inhibition and Antioxidant Potential.
    Abd El Razik HA; Badr MH; Atta AH; Mouneir SM; Abu-Serie MM
    Arch Pharm (Weinheim); 2017 May; 350(5):. PubMed ID: 28418202
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pyrazole-hydrazone derivatives as anti-inflammatory agents: Design, synthesis, biological evaluation, COX-1,2/5-LOX inhibition and docking study.
    Abdelgawad MA; Labib MB; Abdel-Latif M
    Bioorg Chem; 2017 Oct; 74():212-220. PubMed ID: 28865292
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study.
    El-Miligy MMM; Hazzaa AA; El-Messmary H; Nassra RA; El-Hawash SAM
    Bioorg Chem; 2017 Jun; 72():102-115. PubMed ID: 28390993
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, anti-inflammatory screening, molecular docking, and COX-1,2/-5-LOX inhibition profile of some novel quinoline derivatives.
    Chaaban I; Rizk OH; Ibrahim TM; Henen SS; El-Khawass EM; Bayad AE; El-Ashmawy IM; Nematalla HA
    Bioorg Chem; 2018 Aug; 78():220-235. PubMed ID: 29602046
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, biological evaluation and docking study of novel indole-2-amide as anti-inflammatory agents with dual inhibition of COX and 5-LOX.
    Huang Y; Zhang B; Li J; Liu H; Zhang Y; Yang Z; Liu W
    Eur J Med Chem; 2019 Oct; 180():41-50. PubMed ID: 31299586
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, analgesic, anti-inflammatory activity of novel pyrazolones possessing aminosulfonyl pharmacophore as inhibitors of COX-2/5-LOX enzymes: Histopathological and docking studies.
    Abdelgawad MA; Labib MB; Ali WAM; Kamel G; Azouz AA; El-Nahass ES
    Bioorg Chem; 2018 Aug; 78():103-114. PubMed ID: 29550530
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
    Rao PN; Chen QH; Knaus EE
    J Med Chem; 2006 Mar; 49(5):1668-83. PubMed ID: 16509583
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel click modifiable thioquinazolinones as anti-inflammatory agents: Design, synthesis, biological evaluation and docking study.
    Moussa G; Alaaeddine R; Alaeddine LM; Nassra R; Belal ASF; Ismail A; El-Yazbi AF; Abdel-Ghany YS; Hazzaa A
    Eur J Med Chem; 2018 Jan; 144():635-650. PubMed ID: 29289887
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New benzothiophene derivatives as dual COX-1/2 and 5-LOX inhibitors: synthesis, biological evaluation and docking study.
    El-Miligy MM; Hazzaa AA; El-Messmary H; Nassra RA; El-Hawash SA
    Future Med Chem; 2017 Apr; 9(5):443-468. PubMed ID: 28362117
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of new 2-(3-(naphthalen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)thiazole derivatives with potential analgesic and anti-inflammatory activities: In vitro, in vivo and in silico investigations.
    Mohammed ER; Abd-El-Fatah AH; Mohamed AR; Mahrouse MA; Mohammad MA
    Bioorg Chem; 2024 Jun; 147():107372. PubMed ID: 38653152
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel N-substituted 5-aminosalicylamides as dual inhibitors of cyclooxygenase and 5-lipoxygenase enzymes: Synthesis, biological evaluation and docking study.
    El-Nagar MKS; Abdu-Allah HHM; Salem OIA; Kafafy AN; Farghaly HSM
    Bioorg Chem; 2018 Aug; 78():80-93. PubMed ID: 29550533
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and mechanistic study of novel diarylpyrazole derivatives as anti-inflammatory agents with reduced cardiovascular side effects.
    Amin NH; Hamed MIA; Abdel-Fattah MM; Abusabaa AHA; El-Saadi MT
    Bioorg Chem; 2021 Nov; 116():105394. PubMed ID: 34619468
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis and molecular docking of benzophenone conjugated with oxadiazole sulphur bridge pyrazole pharmacophores as anti inflammatory and analgesic agents.
    Zabiulla ; Gulnaz AR; Mohammed YHE; Khanum SA
    Bioorg Chem; 2019 Nov; 92():103220. PubMed ID: 31493708
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, Anti-Inflammatory Activity, and COX-1/2 Inhibition Profile of Some Novel Non-Acidic Polysubstituted Pyrazoles and Pyrano[2,3-c]pyrazoles.
    Faidallah HM; Rostom SAF
    Arch Pharm (Weinheim); 2017 May; 350(5):. PubMed ID: 28370254
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and biological evaluation of some novel indolizine derivatives as dual cyclooxygenase and lipoxygenase inhibitor for anti-inflammatory activity.
    Shrivastava SK; Srivastava P; Bandresh R; Tripathi PN; Tripathi A
    Bioorg Med Chem; 2017 Aug; 25(16):4424-4432. PubMed ID: 28669741
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of new pyrazolone-pyridazine conjugates as anti-inflammatory and analgesic agents.
    Khalil NA; Ahmed EM; Mohamed KO; Nissan YM; Zaitone SA
    Bioorg Med Chem; 2014 Apr; 22(7):2080-9. PubMed ID: 24631365
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cyclooxygenase-2 and 15-lipoxygenase inhibition, synthesis, anti-inflammatory activity and ulcer liability of new celecoxib analogues: Determination of region-specific pyrazole ring formation by NOESY.
    Abdelall EKA; Lamie PF; Ali WAM
    Bioorg Med Chem Lett; 2016 Jun; 26(12):2893-2899. PubMed ID: 27158139
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis and biological evaluation of novel pyrazole sulfonamide derivatives as dual COX-2/5-LOX inhibitors.
    Gedawy EM; Kassab AE; El Kerdawy AM
    Eur J Med Chem; 2020 Mar; 189():112066. PubMed ID: 31982653
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rational design, synthesis and evaluation of chromone-indole and chromone-pyrazole based conjugates: identification of a lead for anti-inflammatory drug.
    Shaveta ; Singh A; Kaur M; Sharma S; Bhatti R; Singh P
    Eur J Med Chem; 2014 Apr; 77():185-92. PubMed ID: 24631898
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, anti-inflammatory, analgesic, 5-lipoxygenase (5-LOX) inhibition activities, and molecular docking study of 7-substituted coumarin derivatives.
    Srivastava P; Vyas VK; Variya B; Patel P; Qureshi G; Ghate M
    Bioorg Chem; 2016 Aug; 67():130-8. PubMed ID: 27376460
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.