220 related articles for article (PubMed ID: 28419165)
21. Hot-spot analysis to dissect the functional protein-protein interface of a tRNA-modifying enzyme.
Jakobi S; Nguyen TX; Debaene F; Metz A; Sanglier-Cianférani S; Reuter K; Klebe G
Proteins; 2014 Oct; 82(10):2713-32. PubMed ID: 24975703
[TBL] [Abstract][Full Text] [Related]
22. Replacement of water molecules in a phosphate binding site by furanoside-appended lin-benzoguanine ligands of tRNA-guanine transglycosylase (TGT).
Barandun LJ; Ehrmann FR; Zimmerli D; Immekus F; Giroud M; Grünenfelder C; Schweizer WB; Bernet B; Betz M; Heine A; Klebe G; Diederich F
Chemistry; 2015 Jan; 21(1):126-35. PubMed ID: 25483606
[TBL] [Abstract][Full Text] [Related]
23. Unraveling a Ligand-Induced Twist of a Homodimeric Enzyme by Pulsed Electron-Electron Double Resonance.
Nguyen D; Abdullin D; Heubach CA; Pfaffeneder T; Nguyen A; Heine A; Reuter K; Diederich F; Schiemann O; Klebe G
Angew Chem Int Ed Engl; 2021 Oct; 60(43):23419-23426. PubMed ID: 34387025
[TBL] [Abstract][Full Text] [Related]
24. Swapping Interface Contacts in the Homodimeric tRNA-Guanine Transglycosylase: An Option for Functional Regulation.
Ehrmann FR; Kalim J; Pfaffeneder T; Bernet B; Hohn C; Schäfer E; Botzanowski T; Cianférani S; Heine A; Reuter K; Diederich F; Klebe G
Angew Chem Int Ed Engl; 2018 Aug; 57(32):10085-10090. PubMed ID: 29927035
[TBL] [Abstract][Full Text] [Related]
25. Crystallographic study of inhibitors of tRNA-guanine transglycosylase suggests a new structure-based pharmacophore for virtual screening.
Brenk R; Meyer EA; Reuter K; Stubbs MT; Garcia GA; Diederich F; Klebe G
J Mol Biol; 2004 Apr; 338(1):55-75. PubMed ID: 15050823
[TBL] [Abstract][Full Text] [Related]
26. Crystal Structure of the Human tRNA Guanine Transglycosylase Catalytic Subunit QTRT1.
Johannsson S; Neumann P; Ficner R
Biomolecules; 2018 Aug; 8(3):. PubMed ID: 30149595
[TBL] [Abstract][Full Text] [Related]
27. Crystal structure of tRNA-guanine transglycosylase: RNA modification by base exchange.
Romier C; Reuter K; Suck D; Ficner R
EMBO J; 1996 Jun; 15(11):2850-7. PubMed ID: 8654383
[TBL] [Abstract][Full Text] [Related]
28. Chemical trapping and crystal structure of a catalytic tRNA guanine transglycosylase covalent intermediate.
Xie W; Liu X; Huang RH
Nat Struct Biol; 2003 Oct; 10(10):781-8. PubMed ID: 12949492
[TBL] [Abstract][Full Text] [Related]
29. Virtual screening for submicromolar leads of tRNA-guanine transglycosylase based on a new unexpected binding mode detected by crystal structure analysis.
Brenk R; Naerum L; Grädler U; Gerber HD; Garcia GA; Reuter K; Stubbs MT; Klebe G
J Med Chem; 2003 Mar; 46(7):1133-43. PubMed ID: 12646024
[TBL] [Abstract][Full Text] [Related]
30. Beyond affinity: enthalpy-entropy factorization unravels complexity of a flat structure-activity relationship for inhibition of a tRNA-modifying enzyme.
Neeb M; Betz M; Heine A; Barandun LJ; Hohn C; Diederich F; Klebe G
J Med Chem; 2014 Jul; 57(13):5566-78. PubMed ID: 24960372
[TBL] [Abstract][Full Text] [Related]
31. Homodimer Architecture of QTRT2, the Noncatalytic Subunit of the Eukaryotic tRNA-Guanine Transglycosylase.
Behrens C; Biela I; Petiot-Bécard S; Botzanowski T; Cianférani S; Sager CP; Klebe G; Heine A; Reuter K
Biochemistry; 2018 Jul; 57(26):3953-3965. PubMed ID: 29862811
[TBL] [Abstract][Full Text] [Related]
32. Crystal structure of archaeosine tRNA-guanine transglycosylase.
Ishitani R; Nureki O; Fukai S; Kijimoto T; Nameki N; Watanabe M; Kondo H; Sekine M; Okada N; Nishimura S; Yokoyama S
J Mol Biol; 2002 May; 318(3):665-77. PubMed ID: 12054814
[TBL] [Abstract][Full Text] [Related]
33. Purification, crystallization, and preliminary x-ray diffraction studies of tRNA-guanine transglycosylase from Zymomonas mobilis.
Romier C; Ficner R; Reuter K; Suck D
Proteins; 1996 Apr; 24(4):516-9. PubMed ID: 8860000
[TBL] [Abstract][Full Text] [Related]
34. Fragment Screening Hit Draws Attention to a Novel Transient Pocket Adjacent to the Recognition Site of the tRNA-Modifying Enzyme TGT.
Hassaan E; Hohn C; Ehrmann FR; Goetzke FW; Movsisyan L; Hüfner-Wulsdorf T; Sebastiani M; Härtsch A; Reuter K; Diederich F; Klebe G
J Med Chem; 2020 Jul; 63(13):6802-6820. PubMed ID: 32515955
[TBL] [Abstract][Full Text] [Related]
35. tRNA recognition by tRNA-guanine transglycosylase from Escherichia coli: the role of U33 in U-G-U sequence recognition.
Nonekowski ST; Garcia GA
RNA; 2001 Oct; 7(10):1432-41. PubMed ID: 11680848
[TBL] [Abstract][Full Text] [Related]
36. De novo design, synthesis, and in vitro evaluation of inhibitors for prokaryotic tRNA-guanine transglycosylase: a dramatic sulfur effect on binding affinity.
Meyer EA; Brenk R; Castellano RK; Furler M; Klebe G; Diederich F
Chembiochem; 2002 Mar; 3(2-3):250-3. PubMed ID: 11921407
[No Abstract] [Full Text] [Related]
37. Identification of Plasmodium falciparum apicoplast-targeted tRNA-guanine transglycosylase and its potential inhibitors using comparative genomics, molecular modelling, docking and simulation studies.
Sawhney B; Chopra K; Misra R; Ranjan A
J Biomol Struct Dyn; 2015; 33(11):2404-20. PubMed ID: 25869381
[TBL] [Abstract][Full Text] [Related]
38. tRNA-guanine transglycosylase from Escherichia coli: recognition of full-length 'queuine-cognate' tRNAs.
Kung FL; Garcia GA
FEBS Lett; 1998 Jul; 431(3):427-32. PubMed ID: 9714557
[TBL] [Abstract][Full Text] [Related]
39. An essential role for aspartate 264 in catalysis by tRNA-guanine transglycosylase from Escherichia coli.
Kittendorf JD; Sgraja T; Reuter K; Klebe G; Garcia GA
J Biol Chem; 2003 Oct; 278(43):42369-76. PubMed ID: 12909636
[TBL] [Abstract][Full Text] [Related]
40. Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase to elucidate the role of serine 103 for enzymatic activity.
Grädler U; Ficner R; Garcia GA; Stubbs MT; Klebe G; Reuter K
FEBS Lett; 1999 Jul; 454(1-2):142-6. PubMed ID: 10413112
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
