BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

261 related articles for article (PubMed ID: 28423230)

  • 1. Gain-of-function p53 activates multiple signaling pathways to induce oncogenicity in lung cancer cells.
    Vaughan CA; Singh S; Grossman SR; Windle B; Deb SP; Deb S
    Mol Oncol; 2017 Jun; 11(6):696-711. PubMed ID: 28423230
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gain-of-function mutant p53 upregulates CXC chemokines and enhances cell migration.
    Yeudall WA; Vaughan CA; Miyazaki H; Ramamoorthy M; Choi MY; Chapman CG; Wang H; Black E; Bulysheva AA; Deb SP; Windle B; Deb S
    Carcinogenesis; 2012 Feb; 33(2):442-51. PubMed ID: 22114072
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Addiction of lung cancer cells to GOF p53 is promoted by up-regulation of epidermal growth factor receptor through multiple contacts with p53 transactivation domain and promoter.
    Vaughan CA; Pearsall I; Singh S; Windle B; Deb SP; Grossman SR; Yeudall WA; Deb S
    Oncotarget; 2016 Mar; 7(11):12426-46. PubMed ID: 26820293
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gain-of-function mutant p53 promotes the oncogenic potential of head and neck squamous cell carcinoma cells by targeting the transcription factors FOXO3a and FOXM1.
    Tanaka N; Zhao M; Tang L; Patel AA; Xi Q; Van HT; Takahashi H; Osman AA; Zhang J; Wang J; Myers JN; Zhou G
    Oncogene; 2018 Mar; 37(10):1279-1292. PubMed ID: 29269868
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis.
    Singh S; Kumar M; Kumar S; Sen S; Upadhyay P; Bhattacharjee S; M N; Tomar VS; Roy S; Dutt A; Kundu TK
    J Biol Chem; 2019 Sep; 294(38):14081-14095. PubMed ID: 31366730
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment of PLK3.
    Vaughan CA; Singh S; Subler MA; Windle JJ; Inoue K; Fry EA; Pillappa R; Grossman SR; Windle B; Andrew Yeudall W; Deb SP; Deb S
    Nat Commun; 2021 Jan; 12(1):704. PubMed ID: 33514736
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p53 mutants induce transcription of NF-κB2 in H1299 cells through CBP and STAT binding on the NF-κB2 promoter and gain of function activity.
    Vaughan CA; Singh S; Windle B; Sankala HM; Graves PR; Andrew Yeudall W; Deb SP; Deb S
    Arch Biochem Biophys; 2012 Feb; 518(1):79-88. PubMed ID: 22198284
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of glucosylceramide synthase eliminates the oncogenic function of p53 R273H mutant in the epithelial-mesenchymal transition and induced pluripotency of colon cancer cells.
    Hosain SB; Khiste SK; Uddin MB; Vorubindi V; Ingram C; Zhang S; Hill RA; Gu X; Liu YY
    Oncotarget; 2016 Sep; 7(37):60575-60592. PubMed ID: 27517620
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chloroquine induces transitory attenuation of proliferation of human lung cancer cells through regulation of mutant P53 and YAP.
    Saini H; Choudhary M; Sharma H; Chowdhury S; Mukherjee S; Chowdhury R
    Mol Biol Rep; 2023 Feb; 50(2):1045-1058. PubMed ID: 36385665
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Plakoglobin restores tumor suppressor activity of p53
    Alaee M; Nool K; Pasdar M
    Cancer Sci; 2018 Jun; 109(6):1876-1888. PubMed ID: 29660231
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MicroRNA-324-5p-CUEDC2 Axis Mediates Gain-of-Function Mutant p53-Driven Cancer Stemness.
    Ghatak D; Datta A; Roychowdhury T; Chattopadhyay S; Roychoudhury S
    Mol Cancer Res; 2021 Oct; 19(10):1635-1650. PubMed ID: 34257080
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The lung-enriched p53 mutants V157F and R158L/P regulate a gain of function transcriptome in lung cancer.
    Barta JA; Pauley K; Kossenkov AV; McMahon SB
    Carcinogenesis; 2020 Mar; 41(1):67-77. PubMed ID: 31067569
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker.
    Kolukula VK; Sahu G; Wellstein A; Rodriguez OC; Preet A; Iacobazzi V; D'Orazi G; Albanese C; Palmieri F; Avantaggiati ML
    Oncotarget; 2014 Mar; 5(5):1212-25. PubMed ID: 24681808
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SOX30, a novel epigenetic silenced tumor suppressor, promotes tumor cell apoptosis by transcriptional activating p53 in lung cancer.
    Han F; Liu W; Jiang X; Shi X; Yin L; Ao L; Cui Z; Li Y; Huang C; Cao J; Liu J
    Oncogene; 2015 Aug; 34(33):4391-402. PubMed ID: 25435374
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Allele specific gain-of-function activity of p53 mutants in lung cancer cells.
    Vaughan CA; Frum R; Pearsall I; Singh S; Windle B; Yeudall A; Deb SP; Deb S
    Biochem Biophys Res Commun; 2012 Nov; 428(1):6-10. PubMed ID: 22989750
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The activating transcription factor 3 protein suppresses the oncogenic function of mutant p53 proteins.
    Wei S; Wang H; Lu C; Malmut S; Zhang J; Ren S; Yu G; Wang W; Tang DD; Yan C
    J Biol Chem; 2014 Mar; 289(13):8947-59. PubMed ID: 24554706
    [TBL] [Abstract][Full Text] [Related]  

  • 17. EZH2 cooperates with gain-of-function p53 mutants to promote cancer growth and metastasis.
    Zhao Y; Ding L; Wang D; Ye Z; He Y; Ma L; Zhu R; Pan Y; Wu Q; Pang K; Hou X; Weroha SJ; Han C; Coleman R; Coleman I; Karnes RJ; Zhang J; Nelson PS; Wang L; Huang H
    EMBO J; 2019 Mar; 38(5):. PubMed ID: 30723117
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p53 gain-of-function mutations increase Cdc7-dependent replication initiation.
    Datta A; Ghatak D; Das S; Banerjee T; Paul A; Butti R; Gorain M; Ghuwalewala S; Roychowdhury A; Alam SK; Das P; Chatterjee R; Dasgupta M; Panda CK; Kundu GC; Roychoudhury S
    EMBO Rep; 2017 Nov; 18(11):2030-2050. PubMed ID: 28887320
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Gain of function mutant p53 protein activates AKT through the Rac1 signaling to promote tumorigenesis.
    Yue X; Wu F; Li Y; Liu J; Boateng M; Mandava K; Zhang C; Feng Z; Gao J; Hu W
    Cell Cycle; 2020 Jun; 19(11):1338-1351. PubMed ID: 32275841
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modulation of gene expression by tumor-derived p53 mutants.
    Scian MJ; Stagliano KE; Ellis MA; Hassan S; Bowman M; Miles MF; Deb SP; Deb S
    Cancer Res; 2004 Oct; 64(20):7447-54. PubMed ID: 15492269
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.