121 related articles for article (PubMed ID: 28427090)
1. The Aldosterone Synthase Inhibitor FAD286 is Suitable for Lowering Aldosterone Levels in ZDF Rats but not in db/db Mice.
Hofmann A; Brunssen C; Peitzsch M; Balyura M; Mittag J; Frenzel A; Jannasch A; Brown NF; Weldon SM; Gueneva-Boucheva KK; Eisenhofer G; Bornstein SR; Morawietz H
Horm Metab Res; 2017 Jun; 49(6):466-471. PubMed ID: 28427090
[TBL] [Abstract][Full Text] [Related]
2. Aldosterone Synthase Inhibition Improves Glucose Tolerance in Zucker Diabetic Fatty (ZDF) Rats.
Hofmann A; Brunssen C; Peitzsch M; Martin M; Mittag J; Jannasch A; Engelmann F; Brown NF; Weldon SM; Huber J; Streicher R; Deussen A; Eisenhofer G; Bornstein SR; Morawietz H
Endocrinology; 2016 Oct; 157(10):3844-3855. PubMed ID: 27526033
[TBL] [Abstract][Full Text] [Related]
3. Impact of Aldosterone Synthase Inhibitor FAD286 on Steroid Hormone Profile in Human Adrenocortical Cells.
Brunssen C; Hofmann A; Peitzsch M; Frenzel A; Ziegler CG; Brown NF; Weldon SM; Eisenhofer G; Willenberg HS; Bornstein SR; Morawietz H
Horm Metab Res; 2017 Sep; 49(9):701-706. PubMed ID: 28759940
[TBL] [Abstract][Full Text] [Related]
4. Selectivity of BI 689648, a Novel, Highly Selective Aldosterone Synthase Inhibitor: Comparison with FAD286 and LCI699 in Nonhuman Primates.
Weldon SM; Cerny MA; Gueneva-Boucheva K; Cogan D; Guo X; Moss N; Parmentier JH; Richman JR; Reinhart GA; Brown NF
J Pharmacol Exp Ther; 2016 Oct; 359(1):142-50. PubMed ID: 27481775
[TBL] [Abstract][Full Text] [Related]
5. Neovascularization is attenuated with aldosterone synthase inhibition in rats with retinopathy.
Deliyanti D; Miller AG; Tan G; Binger KJ; Samson AL; Wilkinson-Berka JL
Hypertension; 2012 Mar; 59(3):607-13. PubMed ID: 22275532
[TBL] [Abstract][Full Text] [Related]
6. Aldosterone synthase inhibition in humans.
Azizi M; Amar L; Menard J
Nephrol Dial Transplant; 2013 Jan; 28(1):36-43. PubMed ID: 23045428
[TBL] [Abstract][Full Text] [Related]
7. Increased aldosterone levels in a model of type 2 diabetes mellitus.
Fredersdorf S; Endemann DH; Luchner A; Heitzmann D; Ulucan C; Birner C; Schmid P; Stoelcker B; Resch M; Muders F; Riegger GA; Weil J
Exp Clin Endocrinol Diabetes; 2009 Jan; 117(1):15-20. PubMed ID: 18726873
[TBL] [Abstract][Full Text] [Related]
8. Adverse effects of an aldosterone synthase (CYP11B2) inhibitor, fadrozole (FAD286), on inflamed rat colon.
Launonen H; Luiskari L; Linden J; Siltari A; Salmenkari H; Korpela R; Vapaatalo H
Basic Clin Pharmacol Toxicol; 2023 Sep; 133(3):211-225. PubMed ID: 37345281
[TBL] [Abstract][Full Text] [Related]
9. Role of brain corticosterone and aldosterone in central angiotensin II-induced hypertension.
Huang BS; White RA; Ahmad M; Leenen FH
Hypertension; 2013 Sep; 62(3):564-71. PubMed ID: 23856493
[TBL] [Abstract][Full Text] [Related]
10. Central infusion of aldosterone synthase inhibitor prevents sympathetic hyperactivity and hypertension by central Na+ in Wistar rats.
Huang BS; White RA; Ahmad M; Jeng AY; Leenen FH
Am J Physiol Regul Integr Comp Physiol; 2008 Jul; 295(1):R166-72. PubMed ID: 18495825
[TBL] [Abstract][Full Text] [Related]
11. Pharmacodynamic and pharmacokinetic characterization of the aldosterone synthase inhibitor FAD286 in two rodent models of hyperaldosteronism: comparison with the 11beta-hydroxylase inhibitor metyrapone.
Rigel DF; Fu F; Beil M; Hu CW; Liang G; Jeng AY
J Pharmacol Exp Ther; 2010 Jul; 334(1):232-43. PubMed ID: 20354176
[TBL] [Abstract][Full Text] [Related]
12. Elevated Steroid Hormone Production in the db/db Mouse Model of Obesity and Type 2 Diabetes.
Hofmann A; Peitzsch M; Brunssen C; Mittag J; Jannasch A; Frenzel A; Brown N; Weldon SM; Eisenhofer G; Bornstein SR; Morawietz H
Horm Metab Res; 2017 Jan; 49(1):43-49. PubMed ID: 27813053
[TBL] [Abstract][Full Text] [Related]
13. Dietary potassium supplementation and sodium restriction stimulate aldosterone synthase but not 11 beta-hydroxylase P-450 messenger ribonucleic acid accumulation in rat adrenals and require angiotensin II production.
Tremblay A; Parker KL; Lehoux JG
Endocrinology; 1992 Jun; 130(6):3152-8. PubMed ID: 1597135
[TBL] [Abstract][Full Text] [Related]
14. Rhesus monkey model for concurrent analyses of in vivo selectivity, pharmacokinetics and pharmacodynamics of aldosterone synthase inhibitors.
Cai TQ; Stribling S; Tong X; Xu L; Wisniewski T; Fontenot JA; Struthers M; Akinsanya KO
J Pharmacol Toxicol Methods; 2015; 71():137-46. PubMed ID: 25304940
[TBL] [Abstract][Full Text] [Related]
15. Differences in plasma homocysteine levels between Zucker fatty and Zucker diabetic fatty rats following 3 weeks oral administration of organic vanadium compounds.
Wasan KM; Risovic V; Yuen VG; McNeill JH
J Trace Elem Med Biol; 2006; 19(4):251-8. PubMed ID: 16443173
[TBL] [Abstract][Full Text] [Related]
16. Myocardial production of aldosterone and corticosterone in the rat. Physiological regulation.
Silvestre JS; Robert V; Heymes C; Aupetit-Faisant B; Mouas C; Moalic JM; Swynghedauw B; Delcayre C
J Biol Chem; 1998 Feb; 273(9):4883-91. PubMed ID: 9478930
[TBL] [Abstract][Full Text] [Related]
17. Aldosterone synthase inhibition improves cardiovascular function and structure in rats with heart failure: a comparison with spironolactone.
Mulder P; Mellin V; Favre J; Vercauteren M; Remy-Jouet I; Monteil C; Richard V; Renet S; Henry JP; Jeng AY; Webb RL; Thuillez C
Eur Heart J; 2008 Sep; 29(17):2171-9. PubMed ID: 18586661
[TBL] [Abstract][Full Text] [Related]
18. Improved metabolic status and insulin sensitivity in obese fatty (fa/fa) Zucker rats and Zucker Diabetic Fatty (ZDF) rats treated with the thiazolidinedione, MCC-555.
Upton R; Widdowson PS; Ishii S; Tanaka H; Williams G
Br J Pharmacol; 1998 Dec; 125(8):1708-14. PubMed ID: 9886762
[TBL] [Abstract][Full Text] [Related]
19. Development of CYP11B1 and CYP11B2 assays utilizing homogenates of adrenal glands: Utility of monkey as a surrogate for human.
Cerny MA; Csengery A; Schmenk J; Frederick K
J Steroid Biochem Mol Biol; 2015 Nov; 154():197-205. PubMed ID: 26303746
[TBL] [Abstract][Full Text] [Related]
20. Local renal aldosterone production induces inflammation and matrix formation in kidneys of diabetic rats.
Siragy HM; Xue C
Exp Physiol; 2008 Jul; 93(7):817-24. PubMed ID: 18296490
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]