117 related articles for article (PubMed ID: 28427558)
1. A Computational Approach to Identify the Biophysical and Structural Aspects of Methylenetetrahydrofolate Reductase (MTHFR) Mutations (A222V, E429A, and R594Q) Leading to Schizophrenia.
Tanwar H; Sneha P; Thirumal Kumar D; Siva R; Walter CEJ; George Priya Doss C
Adv Protein Chem Struct Biol; 2017; 108():105-125. PubMed ID: 28427558
[TBL] [Abstract][Full Text] [Related]
2. Insights on the structural perturbations in human MTHFR Ala222Val mutant by protein modeling and molecular dynamics.
Abhinand PA; Shaikh F; Bhakat S; Radadiya A; Bhaskar LV; Shah A; Ragunath PK
J Biomol Struct Dyn; 2016; 34(4):892-905. PubMed ID: 26273990
[TBL] [Abstract][Full Text] [Related]
3. Mutational landscape screening of methylene tetrahydrofolate reductase to predict homocystinuria associated variants: An integrative computational approach.
Nagarajan H; Narayanaswamy S; Vetrivel U
Mutat Res; 2020; 819-820():111687. PubMed ID: 31968288
[TBL] [Abstract][Full Text] [Related]
4. The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia.
Guenther BD; Sheppard CA; Tran P; Rozen R; Matthews RG; Ludwig ML
Nat Struct Biol; 1999 Apr; 6(4):359-65. PubMed ID: 10201405
[TBL] [Abstract][Full Text] [Related]
5. Characterization of mutations in severe methylenetetrahydrofolate reductase deficiency reveals an FAD-responsive mutation.
Sibani S; Leclerc D; Weisberg IS; O'Ferrall E; Watkins D; Artigas C; Rosenblatt DS; Rozen R
Hum Mutat; 2003 May; 21(5):509-20. PubMed ID: 12673793
[TBL] [Abstract][Full Text] [Related]
6. Properties and crystal structure of methylenetetrahydrofolate reductase from Thermus thermophilus HB8.
Igari S; Ohtaki A; Yamanaka Y; Sato Y; Yohda M; Odaka M; Noguchi K; Yamada K
PLoS One; 2011; 6(8):e23716. PubMed ID: 21858212
[TBL] [Abstract][Full Text] [Related]
7. Computational analysis for the determination of deleterious nsSNPs in human MTHFR gene.
Desai M; Chauhan JB
Comput Biol Chem; 2018 Jun; 74():20-30. PubMed ID: 29524840
[TBL] [Abstract][Full Text] [Related]
8. The prevalence of folate-remedial MTHFR enzyme variants in humans.
Marini NJ; Gin J; Ziegle J; Keho KH; Ginzinger D; Gilbert DA; Rine J
Proc Natl Acad Sci U S A; 2008 Jun; 105(23):8055-60. PubMed ID: 18523009
[TBL] [Abstract][Full Text] [Related]
9. Association of C677T transition of the human methylenetetrahydrofolate reductase (MTHFR) gene with male infertility.
Karimian M; Colagar AH
Reprod Fertil Dev; 2016 Apr; 28(6):785-94. PubMed ID: 25412139
[TBL] [Abstract][Full Text] [Related]
10. Screening for new MTHFR polymorphisms and NTD risk.
O'Leary VB; Mills JL; Parle-McDermott A; Pangilinan F; Molloy AM; Cox C; Weiler A; Conley M; Kirke PN; Scott JM; Brody LC;
Am J Med Genet A; 2005 Oct; 138A(2):99-106. PubMed ID: 16145688
[TBL] [Abstract][Full Text] [Related]
11. Genetic polymorphisms in the one-carbon metabolism pathway and breast cancer risk: a population-based case-control study and meta-analyses.
Lissowska J; Gaudet MM; Brinton LA; Chanock SJ; Peplonska B; Welch R; Zatonski W; Szeszenia-Dabrowska N; Park S; Sherman M; Garcia-Closas M
Int J Cancer; 2007 Jun; 120(12):2696-703. PubMed ID: 17311260
[TBL] [Abstract][Full Text] [Related]
12. The variant methylenetetrahydrofolate reductase c.1298A>C (p.E429A) is associated with multiple sclerosis in a German case-control study.
Klotz L; Farkas M; Bain N; Keskitalo S; Semmler A; Ineichen B; Jelcic J; Klockgether T; Kölsch H; Weller M; Linnebank M
Neurosci Lett; 2010 Jan; 468(3):183-5. PubMed ID: 19854238
[TBL] [Abstract][Full Text] [Related]
13. Structural perturbations in the Ala --> Val polymorphism of methylenetetrahydrofolate reductase: how binding of folates may protect against inactivation.
Pejchal R; Campbell E; Guenther BD; Lennon BW; Matthews RG; Ludwig ML
Biochemistry; 2006 Apr; 45(15):4808-18. PubMed ID: 16605249
[TBL] [Abstract][Full Text] [Related]
14. Insights into severe 5,10-methylenetetrahydrofolate reductase deficiency: molecular genetic and enzymatic characterization of 76 patients.
Burda P; Schäfer A; Suormala T; Rummel T; Bürer C; Heuberger D; Frapolli M; Giunta C; Sokolová J; Vlášková H; Kožich V; Koch HG; Fowler B; Froese DS; Baumgartner MR
Hum Mutat; 2015 Jun; 36(6):611-21. PubMed ID: 25736335
[TBL] [Abstract][Full Text] [Related]
15. Structural basis of S-adenosylmethionine-dependent allosteric transition from active to inactive states in methylenetetrahydrofolate reductase.
Yamada K; Mendoza J; Koutmos M
Nat Commun; 2024 Jun; 15(1):5167. PubMed ID: 38886362
[TBL] [Abstract][Full Text] [Related]
16. Methylenetetrahydrofolate reductase: biochemical characterization and medical significance.
Trimmer EE
Curr Pharm Des; 2013; 19(14):2574-93. PubMed ID: 23116396
[TBL] [Abstract][Full Text] [Related]
17. C677T and A1298C methylenetetrahydrofolate reductase gene polymorphisms in schizophrenia, bipolar disorder and depression: a meta-analysis of genetic association studies.
Zintzaras E
Psychiatr Genet; 2006 Jun; 16(3):105-15. PubMed ID: 16691128
[TBL] [Abstract][Full Text] [Related]
18. Unique holoenzyme dimers of the tetrameric enzyme Escherichia coli methylenetetrahydrofolate reductase: characterization of structural features associated with modulation of the enzyme's function.
Misra SK; Bhakuni V
Biochemistry; 2003 Apr; 42(13):3921-8. PubMed ID: 12667083
[TBL] [Abstract][Full Text] [Related]
19. Molecular characterization of five patients with homocystinuria due to severe methylenetetrahydrofolate reductase deficiency.
Urreizti R; Moya-García AA; Pino-Ángeles A; Cozar M; Langkilde A; Fanhoe U; Esteves C; Arribas J; Vilaseca MA; Pérez-Dueñas B; Pineda M; González V; Artuch R; Baldellou A; Vilarinho L; Fowler B; Ribes A; Sánchez-Jiménez F; Grinberg D; Balcells S
Clin Genet; 2010 Nov; 78(5):441-8. PubMed ID: 20236116
[TBL] [Abstract][Full Text] [Related]
20. Molecular phylogenetic analysis of methylenetetrahydrofolate reductase family of proteins.
Kasap M; Sazci A; Ergul E; Akpinar G
Mol Phylogenet Evol; 2007 Mar; 42(3):838-46. PubMed ID: 17098450
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]