179 related articles for article (PubMed ID: 28430394)
21. Design, synthesis and biological activity of 3-oxoamino-benzenesulfonamides as selective and reversible LSD1 inhibitors.
Xi J; Xu S; Wu L; Ma T; Liu R; Liu YC; Deng D; Gu Y; Zhou J; Lan F; Zha X
Bioorg Chem; 2017 Jun; 72():182-189. PubMed ID: 28460360
[TBL] [Abstract][Full Text] [Related]
22. PIP2 epigenetically represses rRNA genes transcription interacting with PHF8.
Ulicna L; Kalendova A; Kalasova I; Vacik T; Hozák P
Biochim Biophys Acta Mol Cell Biol Lipids; 2018 Mar; 1863(3):266-275. PubMed ID: 29246768
[TBL] [Abstract][Full Text] [Related]
23. PHD finger protein 2 (PHF2) represses ribosomal RNA gene transcription by antagonizing PHF finger protein 8 (PHF8) and recruiting methyltransferase SUV39H1.
Shi G; Wu M; Fang L; Yu F; Cheng S; Li J; Du JX; Wong J
J Biol Chem; 2014 Oct; 289(43):29691-700. PubMed ID: 25204660
[TBL] [Abstract][Full Text] [Related]
24. Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors.
Lohse B; Nielsen AL; Kristensen JB; Helgstrand C; Cloos PA; Olsen L; Gajhede M; Clausen RP; Kristensen JL
Angew Chem Int Ed Engl; 2011 Sep; 50(39):9100-3. PubMed ID: 21919140
[No Abstract] [Full Text] [Related]
25. Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives.
Westaway SM; Preston AG; Barker MD; Brown F; Brown JA; Campbell M; Chung CW; Diallo H; Douault C; Drewes G; Eagle R; Gordon L; Haslam C; Hayhow TG; Humphreys PG; Joberty G; Katso R; Kruidenier L; Leveridge M; Liddle J; Mosley J; Muelbaier M; Randle R; Rioja I; Rueger A; Seal GA; Sheppard RJ; Singh O; Taylor J; Thomas P; Thomson D; Wilson DM; Lee K; Prinjha RK
J Med Chem; 2016 Feb; 59(4):1357-69. PubMed ID: 26771107
[TBL] [Abstract][Full Text] [Related]
26. Compounds and methods for inhibiting histone demethylases: a patent evaluation of US20160102096A1.
Thaler F; Mercurio C
Expert Opin Ther Pat; 2016 Dec; 26(12):1367-1370. PubMed ID: 27730846
[TBL] [Abstract][Full Text] [Related]
27. Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.
Horton JR; Upadhyay AK; Qi HH; Zhang X; Shi Y; Cheng X
Nat Struct Mol Biol; 2010 Jan; 17(1):38-43. PubMed ID: 20023638
[TBL] [Abstract][Full Text] [Related]
28. Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives.
Westaway SM; Preston AG; Barker MD; Brown F; Brown JA; Campbell M; Chung CW; Drewes G; Eagle R; Garton N; Gordon L; Haslam C; Hayhow TG; Humphreys PG; Joberty G; Katso R; Kruidenier L; Leveridge M; Pemberton M; Rioja I; Seal GA; Shipley T; Singh O; Suckling CJ; Taylor J; Thomas P; Wilson DM; Lee K; Prinjha RK
J Med Chem; 2016 Feb; 59(4):1370-87. PubMed ID: 26771203
[TBL] [Abstract][Full Text] [Related]
29. Plant Homeo Domain Finger Protein 8 Regulates Mesodermal and Cardiac Differentiation of Embryonic Stem Cells Through Mediating the Histone Demethylation of pmaip1.
Tang Y; Hong YZ; Bai HJ; Wu Q; Chen CD; Lang JY; Boheler KR; Yang HT
Stem Cells; 2016 Jun; 34(6):1527-40. PubMed ID: 26866517
[TBL] [Abstract][Full Text] [Related]
30. A functional link between the histone demethylase PHF8 and the transcription factor ZNF711 in X-linked mental retardation.
Kleine-Kohlbrecher D; Christensen J; Vandamme J; Abarrategui I; Bak M; Tommerup N; Shi X; Gozani O; Rappsilber J; Salcini AE; Helin K
Mol Cell; 2010 Apr; 38(2):165-78. PubMed ID: 20346720
[TBL] [Abstract][Full Text] [Related]
31. Activation of lysine-specific demethylase 1 inhibitor peptide by redox-controlled cleavage of a traceless linker.
Amano Y; Umezawa N; Sato S; Watanabe H; Umehara T; Higuchi T
Bioorg Med Chem; 2017 Feb; 25(3):1227-1234. PubMed ID: 28065500
[TBL] [Abstract][Full Text] [Related]
32. Proteomic dissection of LPS-inducible, PHF8-dependent secretome reveals novel roles of PHF8 in TLR4-induced acute inflammation and T cell proliferation.
Erdoğan Ö; Xie L; Wang L; Wu B; Kong Q; Wan Y; Chen X
Sci Rep; 2016 Apr; 6():24833. PubMed ID: 27112199
[TBL] [Abstract][Full Text] [Related]
33. Histone demethylase PHF8 regulates hypoxia signaling through HIF1α and H3K4me3.
Maina PK; Shao P; Jia X; Liu Q; Umesalma S; Marin M; Long D; Concepción-Román S; Qi HH
Biochim Biophys Acta Gene Regul Mech; 2017 Sep; 1860(9):1002-1012. PubMed ID: 28734980
[TBL] [Abstract][Full Text] [Related]
34. 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors.
Bavetsias V; Lanigan RM; Ruda GF; Atrash B; McLaughlin MG; Tumber A; Mok NY; Le Bihan YV; Dempster S; Boxall KJ; Jeganathan F; Hatch SB; Savitsky P; Velupillai S; Krojer T; England KS; Sejberg J; Thai C; Donovan A; Pal A; Scozzafava G; Bennett JM; Kawamura A; Johansson C; Szykowska A; Gileadi C; Burgess-Brown NA; von Delft F; Oppermann U; Walters Z; Shipley J; Raynaud FI; Westaway SM; Prinjha RK; Fedorov O; Burke R; Schofield CJ; Westwood IM; Bountra C; Müller S; van Montfort RL; Brennan PE; Blagg J
J Med Chem; 2016 Feb; 59(4):1388-409. PubMed ID: 26741168
[TBL] [Abstract][Full Text] [Related]
35. PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nepsilon-dimethyl lysine demethylase.
Loenarz C; Ge W; Coleman ML; Rose NR; Cooper CD; Klose RJ; Ratcliffe PJ; Schofield CJ
Hum Mol Genet; 2010 Jan; 19(2):217-22. PubMed ID: 19843542
[TBL] [Abstract][Full Text] [Related]
36. Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion.
Björkman M; Östling P; Härmä V; Virtanen J; Mpindi JP; Rantala J; Mirtti T; Vesterinen T; Lundin M; Sankila A; Rannikko A; Kaivanto E; Kohonen P; Kallioniemi O; Nees M
Oncogene; 2012 Jul; 31(29):3444-56. PubMed ID: 22120715
[TBL] [Abstract][Full Text] [Related]
37. Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: a novel class of irreversible inhibitors of histone demethylase KDM1A.
Vianello P; Botrugno OA; Cappa A; Ciossani G; Dessanti P; Mai A; Mattevi A; Meroni G; Minucci S; Thaler F; Tortorici M; Trifiró P; Valente S; Villa M; Varasi M; Mercurio C
Eur J Med Chem; 2014 Oct; 86():352-63. PubMed ID: 25173853
[TBL] [Abstract][Full Text] [Related]
38. The histone demethylase PHF8 is an oncogenic protein in human non-small cell lung cancer.
Shen Y; Pan X; Zhao H
Biochem Biophys Res Commun; 2014 Aug; 451(1):119-25. PubMed ID: 25065740
[TBL] [Abstract][Full Text] [Related]
39. Inhibitor scaffold for the histone lysine demethylase KDM4C (JMJD2C).
Leurs U; Clausen RP; Kristensen JL; Lohse B
Bioorg Med Chem Lett; 2012 Sep; 22(18):5811-3. PubMed ID: 22917519
[TBL] [Abstract][Full Text] [Related]
40. Identification of catechols as histone-lysine demethylase inhibitors.
Nielsen AL; Kristensen LH; Stephansen KB; Kristensen JB; Helgstrand C; Lees M; Cloos P; Helin K; Gajhede M; Olsen L
FEBS Lett; 2012 Apr; 586(8):1190-4. PubMed ID: 22575654
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]