These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

315 related articles for article (PubMed ID: 28433679)

  • 1. Part I: Design, synthesis and biological evaluation of novel pyrazole-benzimidazole conjugates as checkpoint kinase 2 (Chk2) inhibitors with studying their activities alone and in combination with genotoxic drugs.
    Galal SA; Abdelsamie AS; Shouman SA; Attia YM; Ali HI; Tabll A; El-Shenawy R; El Abd YS; Ali MM; Mahmoud AE; Abdel-Halim AH; Fyiad AA; Girgis AS; El-Diwani HI
    Eur J Med Chem; 2017 Jul; 134():392-405. PubMed ID: 28433679
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Part II: New candidates of pyrazole-benzimidazole conjugates as checkpoint kinase 2 (Chk2) inhibitors.
    Galal SA; Khairat SHM; Ali HI; Shouman SA; Attia YM; Ali MM; Mahmoud AE; Abdel-Halim AH; Fyiad AA; Tabll A; El-Shenawy R; El Abd YS; Ramdan R; El Diwani HI
    Eur J Med Chem; 2018 Jan; 144():859-873. PubMed ID: 29316526
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Part III: Novel checkpoint kinase 2 (Chk2) inhibitors; design, synthesis and biological evaluation of pyrimidine-benzimidazole conjugates.
    Galal SA; Khattab M; Shouman SA; Ramadan R; Kandil OM; Kandil OM; Tabll A; El Abd YS; El-Shenawy R; Attia YM; El-Rashedy AA; El Diwani HI
    Eur J Med Chem; 2018 Feb; 146():687-708. PubMed ID: 29407991
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of stable benzimidazole derivatives bearing pyrazole as anticancer and EGFR receptor inhibitors.
    Akhtar MJ; Khan AA; Ali Z; Dewangan RP; Rafi M; Hassan MQ; Akhtar MS; Siddiqui AA; Partap S; Pasha S; Yar MS
    Bioorg Chem; 2018 Aug; 78():158-169. PubMed ID: 29571113
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and biological evaluation of 1,3-diphenyl-1H-pyrazole derivatives containing benzimidazole skeleton as potential anticancer and apoptosis inducing agents.
    Reddy TS; Kulhari H; Reddy VG; Bansal V; Kamal A; Shukla R
    Eur J Med Chem; 2015 Aug; 101():790-805. PubMed ID: 26231080
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, molecular docking and cytotoxic evaluation of novel 2-furybenzimidazoles as VEGFR-2 inhibitors.
    Abdullaziz MA; Abdel-Mohsen HT; El Kerdawy AM; Ragab FAF; Ali MM; Abu-Bakr SM; Girgis AS; El Diwani HI
    Eur J Med Chem; 2017 Aug; 136():315-329. PubMed ID: 28505536
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular docking simulation and anticancer assessment on human breast carcinoma cell line using novel bis(1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile) and bis(1,4-dihydropyrazolo[4',3':5,6]pyrano[2,3-b]pyridine-6-carbonitrile) derivatives.
    Salama SK; Mohamed MF; Darweesh AF; Elwahy AH; Abdelhamid IA
    Bioorg Chem; 2017 Apr; 71():19-29. PubMed ID: 28143658
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and docking studies of novel antitumor benzimidazoles.
    Omar MA; Shaker YM; Galal SA; Ali MM; Kerwin SM; Li J; Tokuda H; Ramadan RA; El Diwani HI
    Bioorg Med Chem; 2012 Dec; 20(24):6989-7001. PubMed ID: 23123017
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and in vitro antitumor evaluation of novel pyrazole-benzimidazole derivatives.
    Ren B; Liu RC; Ji K; Tang JJ; Gao JM
    Bioorg Med Chem Lett; 2021 Jul; 43():128097. PubMed ID: 33979690
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and biological evaluation of some novel benzothiazole/benzoxazole and/or benzimidazole derivatives incorporating a pyrazole scaffold as antiproliferative agents.
    Abdelgawad MA; Bakr RB; Omar HA
    Bioorg Chem; 2017 Oct; 74():82-90. PubMed ID: 28772160
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dihydropyrazole derivatives as telomerase inhibitors: Structure-based design, synthesis, SAR and anticancer evaluation in vitro and in vivo.
    Wang Y; Cheng FX; Yuan XL; Tang WJ; Shi JB; Liao CZ; Liu XH
    Eur J Med Chem; 2016 Apr; 112():231-251. PubMed ID: 26900656
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Some pyrazole and pyrazolo[3,4-d]pyrimidine derivatives: synthesis and anticancer evaluation.
    Shamroukh AH; Rashad AE; Abdel-Megeid RE; Ali HS; Ali MM
    Arch Pharm (Weinheim); 2014 Aug; 347(8):559-65. PubMed ID: 24801813
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Feedback regulation of methyl methanesulfonate and ultraviolet-sensitive gene clone 81 via ATM/Chk2 pathway contributes to the resistance of MCF-7 breast cancer cells to cisplatin.
    Lv J; Qian Y; Ni X; Xu X; Dong X
    Tumour Biol; 2017 Mar; 39(3):1010428317694307. PubMed ID: 28347251
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of a novel series of chalcones incorporated pyrazole moiety as anticancer and antimicrobial agents.
    Mohamed MF; Mohamed MS; Shouman SA; Fathi MM; Abdelhamid IA
    Appl Biochem Biotechnol; 2012 Nov; 168(5):1153-62. PubMed ID: 22948604
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel series of pyrazole-platinum(II) complexes as potential anti-cancer agents that induce cell cycle arrest and apoptosis in breast cancer cells.
    Czarnomysy R; Surażyński A; Muszynska A; Gornowicz A; Bielawska A; Bielawski K
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):1006-1023. PubMed ID: 29862867
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel pyrazole-based COX-2 inhibitors as potential anticancer agents: Design, synthesis, cytotoxic effect against resistant cancer cells, cell cycle arrest, apoptosis induction and dual EGFR/Topo-1 inhibition.
    Halim PA; Sharkawi SMZ; Labib MB
    Bioorg Chem; 2023 Feb; 131():106273. PubMed ID: 36444790
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological evaluation of benzimidazole-oxindole conjugates as microtubule-targeting agents.
    Kamal A; Nagaseshadri B; Nayak VL; Srinivasulu V; Sathish M; Kapure JS; Suresh Reddy C
    Bioorg Chem; 2015 Dec; 63():72-84. PubMed ID: 26469740
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis, biological evaluation, QSAR analysis and molecular modelling of new thiazol-benzimidazoles as EGFR inhibitors.
    Srour AM; Ahmed NS; Abd El-Karim SS; Anwar MM; El-Hallouty SM
    Bioorg Med Chem; 2020 Sep; 28(18):115657. PubMed ID: 32828424
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 1-(5-Chloro-2-alkoxyphenyl)-3-(5-cyanopyrazin-2-yl)ureas [correction of cyanopyrazi] as potent and selective inhibitors of Chk1 kinase: synthesis, preliminary SAR, and biological activities.
    Wang GT; Li G; Mantei RA; Chen Z; Kovar P; Gu W; Xiao Z; Zhang H; Sham HL; Sowin T; Rosenberg SH; Lin NH
    J Med Chem; 2005 May; 48(9):3118-21. PubMed ID: 15857116
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and biological evaluation of novel benzimidazole-2-substituted phenyl or pyridine propyl ketene derivatives as antitumour agents.
    Wu LT; Jiang Z; Shen JJ; Yi H; Zhan YC; Sha MQ; Wang Z; Xue ST; Li ZR
    Eur J Med Chem; 2016 May; 114():328-36. PubMed ID: 27017265
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.