BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

281 related articles for article (PubMed ID: 28433812)

  • 1. The perlecan-interacting growth factor progranulin regulates ubiquitination, sorting, and lysosomal degradation of sortilin.
    Tanimoto R; Palladino C; Xu SQ; Buraschi S; Neill T; Gomella LG; Peiper SC; Belfiore A; Iozzo RV; Morrione A
    Matrix Biol; 2017 Dec; 64():27-39. PubMed ID: 28433812
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sortilin regulates progranulin action in castration-resistant prostate cancer cells.
    Tanimoto R; Morcavallo A; Terracciano M; Xu SQ; Stefanello M; Buraschi S; Lu KG; Bagley DH; Gomella LG; Scotlandi K; Belfiore A; Iozzo RV; Morrione A
    Endocrinology; 2015 Jan; 156(1):58-70. PubMed ID: 25365768
    [TBL] [Abstract][Full Text] [Related]  

  • 3. C-terminus of progranulin interacts with the beta-propeller region of sortilin to regulate progranulin trafficking.
    Zheng Y; Brady OA; Meng PS; Mao Y; Hu F
    PLoS One; 2011; 6(6):e21023. PubMed ID: 21698296
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Interaction Between Progranulin with Sortilin and the Lysosome.
    Zhou X; Sullivan PM; Paushter DH; Hu F
    Methods Mol Biol; 2018; 1806():269-288. PubMed ID: 29956282
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sortilin inhibition limits secretion-induced progranulin-dependent breast cancer progression and cancer stem cell expansion.
    Rhost S; Hughes É; Harrison H; Rafnsdottir S; Jacobsson H; Gregersson P; Magnusson Y; Fitzpatrick P; Andersson D; Berger K; Ståhlberg A; Landberg G
    Breast Cancer Res; 2018 Nov; 20(1):137. PubMed ID: 30454027
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of progranulin expression and location by sortilin in oxygen-glucose deprivation/reoxygenation injury.
    Wang Y; Wang X; Li Y; Chen D; Liu Z; Zhao Y; Tu L; Wang S
    Neurosci Lett; 2020 Nov; 738():135394. PubMed ID: 32949659
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inter-Species Differences in Regulation of the Progranulin-Sortilin Axis in TDP-43 Cell Models of Neurodegeneration.
    Gumina V; Onesto E; Colombrita C; Maraschi A; Silani V; Ratti A
    Int J Mol Sci; 2019 Nov; 20(23):. PubMed ID: 31766750
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Misregulation of human sortilin splicing leads to the generation of a nonfunctional progranulin receptor.
    Prudencio M; Jansen-West KR; Lee WC; Gendron TF; Zhang YJ; Xu YF; Gass J; Stuani C; Stetler C; Rademakers R; Dickson DW; Buratti E; Petrucelli L
    Proc Natl Acad Sci U S A; 2012 Dec; 109(52):21510-5. PubMed ID: 23236149
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sortilin turnover is mediated by ubiquitination.
    Dumaresq-Doiron K; Jules F; Lefrancois S
    Biochem Biophys Res Commun; 2013 Mar; 433(1):90-5. PubMed ID: 23485461
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.
    Zhou X; Sun L; Bastos de Oliveira F; Qi X; Brown WJ; Smolka MB; Sun Y; Hu F
    J Cell Biol; 2015 Sep; 210(6):991-1002. PubMed ID: 26370502
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tumor co-expression of progranulin and sortilin as a prognostic biomarker in breast cancer.
    Berger K; Rhost S; Rafnsdóttir S; Hughes É; Magnusson Y; Ekholm M; Stål O; Rydén L; Landberg G
    BMC Cancer; 2021 Feb; 21(1):185. PubMed ID: 33618683
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel role for drebrin in regulating progranulin bioactivity in bladder cancer.
    Xu SQ; Buraschi S; Morcavallo A; Genua M; Shirao T; Peiper SC; Gomella LG; Birbe R; Belfiore A; Iozzo RV; Morrione A
    Oncotarget; 2015 May; 6(13):10825-39. PubMed ID: 25839164
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Soluble sortilin is present in excess and positively correlates with progranulin in CSF of aging individuals.
    Molgaard S; Demontis D; Nicholson AM; Finch NA; Petersen RC; Petersen CM; Rademakers R; Nykjaer A; Glerup S
    Exp Gerontol; 2016 Nov; 84():96-100. PubMed ID: 27612602
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin.
    Hu F; Padukkavidana T; Vægter CB; Brady OA; Zheng Y; Mackenzie IR; Feldman HH; Nykjaer A; Strittmatter SM
    Neuron; 2010 Nov; 68(4):654-67. PubMed ID: 21092856
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Neuronal brain-derived neurotrophic factor is synthesized in excess, with levels regulated by sortilin-mediated trafficking and lysosomal degradation.
    Evans SF; Irmady K; Ostrow K; Kim T; Nykjaer A; Saftig P; Blobel C; Hempstead BL
    J Biol Chem; 2011 Aug; 286(34):29556-67. PubMed ID: 21730062
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Upregulation of Sortilin, a Lysosomal Sorting Receptor, Corresponds with Reduced Bioavailability of Latent TGFβ in Mucolipidosis II Cells.
    Barnes JW; Aarnio-Peterson M; Norris J; Haskins M; Flanagan-Steet H; Steet R
    Biomolecules; 2020 Apr; 10(5):. PubMed ID: 32357547
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The inactivation of the sortilin gene leads to a partial disruption of prosaposin trafficking to the lysosomes.
    Zeng J; Racicott J; Morales CR
    Exp Cell Res; 2009 Nov; 315(18):3112-24. PubMed ID: 19732768
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Suppression of progranulin expression inhibits bladder cancer growth and sensitizes cancer cells to cisplatin.
    Buraschi S; Xu SQ; Stefanello M; Moskalev I; Morcavallo A; Genua M; Tanimoto R; Birbe R; Peiper SC; Gomella LG; Belfiore A; Black PC; Iozzo RV; Morrione A
    Oncotarget; 2016 Jun; 7(26):39980-39995. PubMed ID: 27220888
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency.
    Lee WC; Almeida S; Prudencio M; Caulfield TR; Zhang YJ; Tay WM; Bauer PO; Chew J; Sasaguri H; Jansen-West KR; Gendron TF; Stetler CT; Finch N; Mackenzie IR; Rademakers R; Gao FB; Petrucelli L
    Hum Mol Genet; 2014 Mar; 23(6):1467-78. PubMed ID: 24163244
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The intracellular domain of sortilin interacts with amyloid precursor protein and regulates its lysosomal and lipid raft trafficking.
    Yang M; Virassamy B; Vijayaraj SL; Lim Y; Saadipour K; Wang YJ; Han YC; Zhong JH; Morales CR; Zhou XF
    PLoS One; 2013; 8(5):e63049. PubMed ID: 23704887
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.