BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

325 related articles for article (PubMed ID: 28434262)

  • 1. The emergence of acid ceramidase as a therapeutic target for acute myeloid leukemia.
    Tan SF; Pearson JM; Feith DJ; Loughran TP
    Expert Opin Ther Targets; 2017 Jun; 21(6):583-590. PubMed ID: 28434262
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Acid ceramidase is upregulated in AML and represents a novel therapeutic target.
    Tan SF; Liu X; Fox TE; Barth BM; Sharma A; Turner SD; Awwad A; Dewey A; Doi K; Spitzer B; Shah MV; Morad SA; Desai D; Amin S; Zhu J; Liao J; Yun J; Kester M; Claxton DF; Wang HG; Cabot MC; Schuchman EH; Levine RL; Feith DJ; Loughran TP
    Oncotarget; 2016 Dec; 7(50):83208-83222. PubMed ID: 27825124
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation.
    Tan SF; Dunton W; Liu X; Fox TE; Morad SAF; Desai D; Doi K; Conaway MR; Amin S; Claxton DF; Wang HG; Kester M; Cabot MC; Feith DJ; Loughran TP
    J Lipid Res; 2019 Jun; 60(6):1078-1086. PubMed ID: 30962310
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel off-target effect of tamoxifen--inhibition of acid ceramidase activity in cancer cells.
    Morad SA; Levin JC; Tan SF; Fox TE; Feith DJ; Cabot MC
    Biochim Biophys Acta; 2013 Dec; 1831(12):1657-64. PubMed ID: 23939396
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Acid Ceramidase: A Novel Therapeutic Target in Cancer.
    Vijayan Y; Lankadasari MB; Harikumar KB
    Curr Top Med Chem; 2019; 19(17):1512-1520. PubMed ID: 30827244
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acid ceramidase, an emerging target for anti-cancer and anti-angiogenesis.
    Cho SM; Kwon HJ
    Arch Pharm Res; 2019 Mar; 42(3):232-243. PubMed ID: 30661200
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ceramide Analogue SACLAC Modulates Sphingolipid Levels and
    Pearson JM; Tan SF; Sharma A; Annageldiyev C; Fox TE; Abad JL; Fabrias G; Desai D; Amin S; Wang HG; Cabot MC; Claxton DF; Kester M; Feith DJ; Loughran TP
    Mol Cancer Res; 2020 Mar; 18(3):352-363. PubMed ID: 31744877
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of mTOR kinase as a therapeutic target for acute myeloid leukemia.
    Tabe Y; Tafuri A; Sekihara K; Yang H; Konopleva M
    Expert Opin Ther Targets; 2017 Jul; 21(7):705-714. PubMed ID: 28537457
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia--Impact on enzyme activity and response to cytotoxics.
    Morad SA; Tan SF; Feith DJ; Kester M; Claxton DF; Loughran TP; Barth BM; Fox TE; Cabot MC
    Biochim Biophys Acta; 2015 Jul; 1851(7):919-28. PubMed ID: 25769964
    [TBL] [Abstract][Full Text] [Related]  

  • 10. C6-ceramide and targeted inhibition of acid ceramidase induce synergistic decreases in breast cancer cell growth.
    Flowers M; Fabriás G; Delgado A; Casas J; Abad JL; Cabot MC
    Breast Cancer Res Treat; 2012 Jun; 133(2):447-58. PubMed ID: 21935601
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibitors of LSD1 as a potential therapy for acute myeloid leukemia.
    Przespolewski A; Wang ES
    Expert Opin Investig Drugs; 2016 Jul; 25(7):771-80. PubMed ID: 27077938
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cyclin-dependent kinase (CDK) 9 and 4/6 inhibitors in acute myeloid leukemia (AML): a promising therapeutic approach.
    Lee DJ; Zeidner JF
    Expert Opin Investig Drugs; 2019 Nov; 28(11):989-1001. PubMed ID: 31612739
    [No Abstract]   [Full Text] [Related]  

  • 13. Hedgehog pathway inhibition as a therapeutic target in acute myeloid leukemia.
    Shallis RM; Bewersdorf JP; Boddu PC; Zeidan AM
    Expert Rev Anticancer Ther; 2019 Aug; 19(8):717-729. PubMed ID: 31422721
    [No Abstract]   [Full Text] [Related]  

  • 14. Cell cycle inhibitors for the treatment of acute myeloid leukemia: a review of phase 2 & 3 clinical trials.
    Jammal N; Rausch CR; Kadia TM; Pemmaraju N
    Expert Opin Emerg Drugs; 2020 Dec; 25(4):491-499. PubMed ID: 33161749
    [No Abstract]   [Full Text] [Related]  

  • 15. Harnessing the power of sphingolipids: Prospects for acute myeloid leukemia.
    Ung J; Tan SF; Fox TE; Shaw JJP; Vass LR; Costa-Pinheiro P; Garrett-Bakelman FE; Keng MK; Sharma A; Claxton DF; Levine RL; Tallman MS; Cabot MC; Kester M; Feith DJ; Loughran TP
    Blood Rev; 2022 Sep; 55():100950. PubMed ID: 35487785
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells.
    Morad SA; Messner MC; Levin JC; Abdelmageed N; Park H; Merrill AH; Cabot MC
    Cancer Chemother Pharmacol; 2013 Mar; 71(3):635-45. PubMed ID: 23263160
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Splenic tyrosine kinase (SYK) inhibitors and their possible use in acute myeloid leukemia.
    Bartaula-Brevik S; Lindstad Brattås MK; Tvedt THA; Reikvam H; Bruserud Ø
    Expert Opin Investig Drugs; 2018 Apr; 27(4):377-387. PubMed ID: 29611449
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacophore Identification and Scaffold Exploration to Discover Novel, Potent, and Chemically Stable Inhibitors of Acid Ceramidase in Melanoma Cells.
    Ortega JA; Arencibia JM; La Sala G; Borgogno M; Bauer I; Bono L; Braccia C; Armirotti A; Girotto S; Ganesan A; De Vivo M
    J Med Chem; 2017 Jul; 60(13):5800-5815. PubMed ID: 28603987
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ACER3 supports development of acute myeloid leukemia.
    Chen C; Yin Y; Li C; Chen J; Xie J; Lu Z; Li M; Wang Y; Zhang CC
    Biochem Biophys Res Commun; 2016 Sep; 478(1):33-38. PubMed ID: 27470583
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Concurrent targeting Akt and sphingosine kinase 1 by A-674563 in acute myeloid leukemia cells.
    Xu L; Zhang Y; Gao M; Wang G; Fu Y
    Biochem Biophys Res Commun; 2016 Apr; 472(4):662-8. PubMed ID: 26920060
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.