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2. Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes. Ference BA; Robinson JG; Brook RD; Catapano AL; Chapman MJ; Neff DR; Voros S; Giugliano RP; Davey Smith G; Fazio S; Sabatine MS N Engl J Med; 2016 Dec; 375(22):2144-2153. PubMed ID: 27959767 [TBL] [Abstract][Full Text] [Related]
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4. Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study. Gormley M; Yarmolinsky J; Dudding T; Burrows K; Martin RM; Thomas S; Tyrrell J; Brennan P; Pring M; Boccia S; Olshan AF; Diergaarde B; Hung RJ; Liu G; Legge D; Tajara EH; Severino P; Lacko M; Ness AR; Davey Smith G; Vincent EE; Richmond RC PLoS Genet; 2021 Apr; 17(4):e1009525. PubMed ID: 33886544 [TBL] [Abstract][Full Text] [Related]
5. Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer. Yarmolinsky J; Bull CJ; Vincent EE; Robinson J; Walther A; Smith GD; Lewis SJ; Relton CL; Martin RM JAMA; 2020 Feb; 323(7):646-655. PubMed ID: 32068819 [TBL] [Abstract][Full Text] [Related]
7. Association Between Low-Density Lipoprotein Cholesterol-Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis. Lotta LA; Sharp SJ; Burgess S; Perry JRB; Stewart ID; Willems SM; Luan J; Ardanaz E; Arriola L; Balkau B; Boeing H; Deloukas P; Forouhi NG; Franks PW; Grioni S; Kaaks R; Key TJ; Navarro C; Nilsson PM; Overvad K; Palli D; Panico S; Quirós JR; Riboli E; Rolandsson O; Sacerdote C; Salamanca EC; Slimani N; Spijkerman AM; Tjonneland A; Tumino R; van der A DL; van der Schouw YT; McCarthy MI; Barroso I; O'Rahilly S; Savage DB; Sattar N; Langenberg C; Scott RA; Wareham NJ JAMA; 2016 Oct; 316(13):1383-1391. PubMed ID: 27701660 [TBL] [Abstract][Full Text] [Related]
8. Effect of naturally random allocation to lower low-density lipoprotein cholesterol on the risk of coronary heart disease mediated by polymorphisms in NPC1L1, HMGCR, or both: a 2 × 2 factorial Mendelian randomization study. Ference BA; Majeed F; Penumetcha R; Flack JM; Brook RD J Am Coll Cardiol; 2015 Apr; 65(15):1552-61. PubMed ID: 25770315 [TBL] [Abstract][Full Text] [Related]
9. Mendelian Randomization Study of PCSK9 and HMG-CoA Reductase Inhibition and Cognitive Function. Rosoff DB; Bell AS; Jung J; Wagner J; Mavromatis LA; Lohoff FW J Am Coll Cardiol; 2022 Aug; 80(7):653-662. PubMed ID: 35953131 [TBL] [Abstract][Full Text] [Related]
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11. Lipid lowering and Alzheimer disease risk: A mendelian randomization study. Williams DM; Finan C; Schmidt AF; Burgess S; Hingorani AD Ann Neurol; 2020 Jan; 87(1):30-39. PubMed ID: 31714636 [TBL] [Abstract][Full Text] [Related]
12. Impact of glucose on risk of dementia: Mendelian randomisation studies in 115,875 individuals. Benn M; Nordestgaard BG; Tybjærg-Hansen A; Frikke-Schmidt R Diabetologia; 2020 Jun; 63(6):1151-1161. PubMed ID: 32172311 [TBL] [Abstract][Full Text] [Related]
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14. Association of Genetic Variants Related to CETP Inhibitors and Statins With Lipoprotein Levels and Cardiovascular Risk. Ference BA; Kastelein JJP; Ginsberg HN; Chapman MJ; Nicholls SJ; Ray KK; Packard CJ; Laufs U; Brook RD; Oliver-Williams C; Butterworth AS; Danesh J; Smith GD; Catapano AL; Sabatine MS JAMA; 2017 Sep; 318(10):947-956. PubMed ID: 28846118 [TBL] [Abstract][Full Text] [Related]
15. Low LDL Cholesterol by PCSK9 Variation Reduces Cardiovascular Mortality. Benn M; Tybjærg-Hansen A; Nordestgaard BG J Am Coll Cardiol; 2019 Jun; 73(24):3102-3114. PubMed ID: 31221259 [TBL] [Abstract][Full Text] [Related]
16. PCSK9 R46L, low-density lipoprotein cholesterol levels, and risk of ischemic heart disease: 3 independent studies and meta-analyses. Benn M; Nordestgaard BG; Grande P; Schnohr P; Tybjaerg-Hansen A J Am Coll Cardiol; 2010 Jun; 55(25):2833-42. PubMed ID: 20579540 [TBL] [Abstract][Full Text] [Related]
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18. PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study. Schmidt AF; Swerdlow DI; Holmes MV; Patel RS; Fairhurst-Hunter Z; Lyall DM; Hartwig FP; Horta BL; Hyppönen E; Power C; Moldovan M; van Iperen E; Hovingh GK; Demuth I; Norman K; Steinhagen-Thiessen E; Demuth J; Bertram L; Liu T; Coassin S; Willeit J; Kiechl S; Willeit K; Mason D; Wright J; Morris R; Wanamethee G; Whincup P; Ben-Shlomo Y; McLachlan S; Price JF; Kivimaki M; Welch C; Sanchez-Galvez A; Marques-Vidal P; Nicolaides A; Panayiotou AG; Onland-Moret NC; van der Schouw YT; Matullo G; Fiorito G; Guarrera S; Sacerdote C; Wareham NJ; Langenberg C; Scott R; Luan J; Bobak M; Malyutina S; Pająk A; Kubinova R; Tamosiunas A; Pikhart H; Husemoen LL; Grarup N; Pedersen O; Hansen T; Linneberg A; Simonsen KS; Cooper J; Humphries SE; Brilliant M; Kitchner T; Hakonarson H; Carrell DS; McCarty CA; Kirchner HL; Larson EB; Crosslin DR; de Andrade M; Roden DM; Denny JC; Carty C; Hancock S; Attia J; Holliday E; O'Donnell M; Yusuf S; Chong M; Pare G; van der Harst P; Said MA; Eppinga RN; Verweij N; Snieder H; ; Christen T; Mook-Kanamori DO; Gustafsson S; Lind L; Ingelsson E; Pazoki R; Franco O; Hofman A; Uitterlinden A; Dehghan A; Teumer A; Baumeister S; Dörr M; Lerch MM; Völker U; Völzke H; Ward J; Pell JP; Smith DJ; Meade T; Maitland-van der Zee AH; Baranova EV; Young R; Ford I; Campbell A; Padmanabhan S; Bots ML; Grobbee DE; Froguel P; Thuillier D; Balkau B; Bonnefond A; Cariou B; Smart M; Bao Y; Kumari M; Mahajan A; Ridker PM; Chasman DI; Reiner AP; Lange LA; Ritchie MD; Asselbergs FW; Casas JP; Keating BJ; Preiss D; Hingorani AD; ; Sattar N Lancet Diabetes Endocrinol; 2017 Feb; 5(2):97-105. PubMed ID: 27908689 [TBL] [Abstract][Full Text] [Related]
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