BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 28439591)

  • 1. Targeting secondary protein complexes in drug discovery: studying the druggability and chemical biology of the HSP70/BAG1 complex.
    Evans LE; Jones K; Cheeseman MD
    Chem Commun (Camb); 2017 May; 53(37):5167-5170. PubMed ID: 28439591
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting HSP70: the second potentially druggable heat shock protein and molecular chaperone?
    Powers MV; Jones K; Barillari C; Westwood I; van Montfort RL; Workman P
    Cell Cycle; 2010 Apr; 9(8):1542-50. PubMed ID: 20372081
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery and Characterization of a Cryptic Secondary Binding Site in the Molecular Chaperone HSP70.
    O'Connor S; Le Bihan YV; Westwood IM; Liu M; Mak OW; Zazeri G; Povinelli APR; Jones AM; van Montfort R; Reynisson J; Collins I
    Molecules; 2022 Jan; 27(3):. PubMed ID: 35164081
    [TBL] [Abstract][Full Text] [Related]  

  • 4. High-affinity fluorescent ligands for the 5-HT(3) receptor.
    Simonin J; Vernekar SK; Thompson AJ; Hothersall JD; Connolly CN; Lummis SC; Lochner M
    Bioorg Med Chem Lett; 2012 Jan; 22(2):1151-5. PubMed ID: 22189135
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PNA-encoded chemical libraries.
    Zambaldo C; Barluenga S; Winssinger N
    Curr Opin Chem Biol; 2015 Jun; 26():8-15. PubMed ID: 25621730
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Development of a microarray-based assay for efficient testing of new HSP70/DnaK inhibitors.
    Mohammadi-Ostad-Kalayeh S; Hrupins V; Helmsen S; Ahlbrecht C; Stahl F; Scheper T; Preller M; Surup F; Stadler M; Kirschning A; Zeilinger C
    Bioorg Med Chem; 2017 Dec; 25(24):6345-6352. PubMed ID: 29042222
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Aiming to Miss a Moving Target: Bromo and Extra Terminal Domain (BET) Selectivity in Constrained ATAD2 Inhibitors.
    Bamborough P; Chung CW; Furze RC; Grandi P; Michon AM; Watson RJ; Mitchell DJ; Barnett H; Prinjha RK; Rau C; Sheppard RJ; Werner T; Demont EH
    J Med Chem; 2018 Sep; 61(18):8321-8336. PubMed ID: 30226378
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important protein.
    Rodina A; Patel PD; Kang Y; Patel Y; Baaklini I; Wong MJ; Taldone T; Yan P; Yang C; Maharaj R; Gozman A; Patel MR; Patel HJ; Chirico W; Erdjument-Bromage H; Talele TT; Young JC; Chiosis G
    Chem Biol; 2013 Dec; 20(12):1469-80. PubMed ID: 24239008
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development of an ON/OFF switchable fluorescent probe targeting His tag fused proteins in living cells.
    Okitsu K; Misawa T; Shoda T; Kurihara M; Demizu Y
    Bioorg Med Chem Lett; 2017 Aug; 27(15):3417-3422. PubMed ID: 28647351
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New inhibitor targeting human transcription factor HSF1: effects on the heat shock response and tumor cell survival.
    Vilaboa N; Boré A; Martin-Saavedra F; Bayford M; Winfield N; Firth-Clark S; Kirton SB; Voellmy R
    Nucleic Acids Res; 2017 Jun; 45(10):5797-5817. PubMed ID: 28369544
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bag1-Hsp70 mediates a physiological stress signalling pathway that regulates Raf-1/ERK and cell growth.
    Song J; Takeda M; Morimoto RI
    Nat Cell Biol; 2001 Mar; 3(3):276-82. PubMed ID: 11231577
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interaction between the BAG1S isoform and HSP70 mediates the stability of anti-apoptotic proteins and the survival of osteosarcoma cells expressing oncogenic MYC.
    Gennaro VJ; Wedegaertner H; McMahon SB
    BMC Cancer; 2019 Mar; 19(1):258. PubMed ID: 30902071
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of BRD4 bromodomain inhibitors by fragment-based high-throughput docking.
    Zhao H; Gartenmann L; Dong J; Spiliotopoulos D; Caflisch A
    Bioorg Med Chem Lett; 2014 Jun; 24(11):2493-6. PubMed ID: 24767840
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sensitizing tumor cells to radiation by targeting the heat shock response.
    Schilling D; Kühnel A; Konrad S; Tetzlaff F; Bayer C; Yaglom J; Multhoff G
    Cancer Lett; 2015 May; 360(2):294-301. PubMed ID: 25721082
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dual functional small molecule fluorescent probes for image-guided estrogen receptor-specific targeting coupled potent antiproliferative potency for breast cancer therapy.
    Yang L; Hu Z; Luo J; Tang C; Zhang S; Ning W; Dong C; Huang J; Liu X; Zhou HB
    Bioorg Med Chem; 2017 Jul; 25(13):3531-3539. PubMed ID: 28506582
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, Synthesis, and Initial Evaluation of Affinity-Based Small-Molecule Probes for Fluorescent Visualization and Specific Detection of Keap1.
    Lu M; Zhou HS; You QD; Jiang Z
    J Med Chem; 2016 Aug; 59(15):7305-10. PubMed ID: 27409246
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neutral analogs of the heat shock protein 70 (Hsp70) inhibitor, JG-98.
    Shao H; Gestwicki JE
    Bioorg Med Chem Lett; 2020 Mar; 30(5):126954. PubMed ID: 31952963
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Research progress of selective small molecule bromodomain-containing protein 9 inhibitors.
    Hui M; Jian Z; Peiyuan Z; Zhenwei W; Huibin Z
    Future Med Chem; 2018 Apr; 10(8):895-906. PubMed ID: 29620420
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of Small-Molecule Sulfonamide Fluorescent Probes for GPR120.
    Liu P; Ma S; Yan C; Qin X; Zhao P; Li Q; Cui Y; Li M; Du L
    Anal Chem; 2019 Dec; 91(23):15235-15239. PubMed ID: 31691553
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Dynamics of chaperone complex Hdj1-Hsp70-Bag1 as a response of erythroleukemia K562 cells to heat stress].
    Novoselov SS; Novoselova TV; Moskaleva OS; Margulis BA; Guzhova IV
    Tsitologiia; 2004; 46(7):620-7. PubMed ID: 15473372
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.