BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

249 related articles for article (PubMed ID: 28442559)

  • 1. Impact of 27-hydroxylase (CYP27A1) and 27-hydroxycholesterol in breast cancer.
    Kimbung S; Chang CY; Bendahl PO; Dubois L; Thompson JW; McDonnell DP; Borgquist S
    Endocr Relat Cancer; 2017 Jul; 24(7):339-349. PubMed ID: 28442559
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Vitamin D supplementation decreases serum 27-hydroxycholesterol in a pilot breast cancer trial.
    Going CC; Alexandrova L; Lau K; Yeh CY; Feldman D; Pitteri SJ
    Breast Cancer Res Treat; 2018 Feb; 167(3):797-802. PubMed ID: 29116467
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Circulating 27-hydroxycholesterol and breast cancer tissue expression of CYP27A1, CYP7B1, LXR-β, and ERβ: results from the EPIC-Heidelberg cohort.
    Le Cornet C; Walter B; Sookthai D; Johnson TS; Kühn T; Herpel E; Kaaks R; Fortner RT
    Breast Cancer Res; 2020 Feb; 22(1):23. PubMed ID: 32075687
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology.
    Nelson ER; Wardell SE; Jasper JS; Park S; Suchindran S; Howe MK; Carver NJ; Pillai RV; Sullivan PM; Sondhi V; Umetani M; Geradts J; McDonnell DP
    Science; 2013 Nov; 342(6162):1094-8. PubMed ID: 24288332
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CYP27A1 expression is associated with risk of late lethal estrogen receptor-positive breast cancer in postmenopausal patients.
    Kimbung S; Inasu M; Stålhammar T; Nodin B; Elebro K; Tryggvadottir H; Ygland Rödström M; Jirström K; Isaksson K; Jernström H; Borgquist S
    Breast Cancer Res; 2020 Nov; 22(1):123. PubMed ID: 33176848
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 27-Hydroxycholesterol acts on myeloid immune cells to induce T cell dysfunction, promoting breast cancer progression.
    Ma L; Wang L; Nelson AT; Han C; He S; Henn MA; Menon K; Chen JJ; Baek AE; Vardanyan A; Shahoei SH; Park S; Shapiro DJ; Nanjappa SG; Nelson ER
    Cancer Lett; 2020 Nov; 493():266-283. PubMed ID: 32861706
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Host CYP27A1 expression is essential for ovarian cancer progression.
    He S; Ma L; Baek AE; Vardanyan A; Vembar V; Chen JJ; Nelson AT; Burdette JE; Nelson ER
    Endocr Relat Cancer; 2019 Jul; 26(7):659-675. PubMed ID: 31048561
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The cholesterol derivative 27-hydroxycholesterol reduces steatohepatitis in mice.
    Bieghs V; Hendrikx T; van Gorp PJ; Verheyen F; Guichot YD; Walenbergh SM; Jeurissen ML; Gijbels M; Rensen SS; Bast A; Plat J; Kalhan SC; Koek GH; Leitersdorf E; Hofker MH; Lütjohann D; Shiri-Sverdlov R
    Gastroenterology; 2013 Jan; 144(1):167-178.e1. PubMed ID: 23041327
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hematopoietic overexpression of Cyp27a1 reduces hepatic inflammation independently of 27-hydroxycholesterol levels in Ldlr(-/-) mice.
    Hendrikx T; Jeurissen ML; Bieghs V; Walenbergh SM; van Gorp PJ; Verheyen F; Houben T; Guichot YD; Gijbels MJ; Leitersdorf E; Hofker MH; Lütjohann D; Shiri-Sverdlov R
    J Hepatol; 2015 Feb; 62(2):430-6. PubMed ID: 25281859
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Intratumoral Sterol-27-Hydroxylase (
    Khan NA; Stopsack KH; Allott EH; Gerke T; Giovannucci EL; Mucci LA; Kantoff PW
    Cancer Epidemiol Biomarkers Prev; 2019 Jun; 28(6):1052-1058. PubMed ID: 30867220
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Circulating 27-Hydroxycholesterol and Breast Cancer Risk: Results From the EPIC-Heidelberg Cohort.
    Lu DL; Le Cornet C; Sookthai D; Johnson TS; Kaaks R; Fortner RT
    J Natl Cancer Inst; 2019 Apr; 111(4):365-371. PubMed ID: 30016454
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Our evolving understanding of how 27-hydroxycholesterol influences cancer.
    Ma L; Cho W; Nelson ER
    Biochem Pharmacol; 2022 Feb; 196():114621. PubMed ID: 34043965
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer.
    Alfaqih MA; Nelson ER; Liu W; Safi R; Jasper JS; Macias E; Geradts J; Thompson JW; Dubois LG; Freeman MR; Chang CY; Chi JT; McDonnell DP; Freedland SJ
    Cancer Res; 2017 Apr; 77(7):1662-1673. PubMed ID: 28130224
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The estrogen receptor as a mediator of the pathological actions of cholesterol in breast cancer.
    McDonnell DP; Chang CY; Nelson ER
    Climacteric; 2014 Dec; 17 Suppl 2(0 2):60-5. PubMed ID: 25320023
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CYP27A1 inhibits bladder cancer cells proliferation by regulating cholesterol homeostasis.
    Liang Z; Chen Y; Wang L; Li D; Yang X; Ma G; Wang Y; Li Y; Zhao H; Liang Y; Niu H
    Cell Cycle; 2019 Jan; 18(1):34-45. PubMed ID: 30563407
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cholesterol neutralized vemurafenib treatment by promoting melanoma stem-like cells via its metabolite 27-hydroxycholesterol.
    Wang X; Zhong F; Chen T; Wang H; Wang W; Jin H; Li C; Guo X; Liu Y; Zhang Y; Li B
    Cell Mol Life Sci; 2024 May; 81(1):226. PubMed ID: 38775844
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.
    Wu Q; Ishikawa T; Sirianni R; Tang H; McDonald JG; Yuhanna IS; Thompson B; Girard L; Mineo C; Brekken RA; Umetani M; Euhus DM; Xie Y; Shaul PW
    Cell Rep; 2013 Nov; 5(3):637-45. PubMed ID: 24210818
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 27-Hydroxylation of oncosterone by CYP27A1 switches its activity from pro-tumor to anti-tumor.
    Ayadi S; Friedrichs S; Soulès R; Pucheu L; Lütjohann D; Silvente-Poirot S; Poirot M; de Medina P
    J Lipid Res; 2023 Dec; 64(12):100479. PubMed ID: 37981011
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis.
    DuSell CD; Nelson ER; Wang X; Abdo J; Mödder UI; Umetani M; Gesty-Palmer D; Javitt NB; Khosla S; McDonnell DP
    Endocrinology; 2010 Aug; 151(8):3675-85. PubMed ID: 20501668
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells.
    Baek AE; Yu YA; He S; Wardell SE; Chang CY; Kwon S; Pillai RV; McDowell HB; Thompson JW; Dubois LG; Sullivan PM; Kemper JK; Gunn MD; McDonnell DP; Nelson ER
    Nat Commun; 2017 Oct; 8(1):864. PubMed ID: 29021522
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.