These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

260 related articles for article (PubMed ID: 28442573)

  • 1. Cell cycle-dependent degradation of the methyltransferase SETD3 attenuates cell proliferation and liver tumorigenesis.
    Cheng X; Hao Y; Shu W; Zhao M; Zhao C; Wu Y; Peng X; Yao P; Xiao D; Qing G; Pan Z; Yin L; Hu D; Du HN
    J Biol Chem; 2017 Jun; 292(22):9022-9033. PubMed ID: 28442573
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A colon cancer-derived mutant of Krüppel-like factor 5 (KLF5) is resistant to degradation by glycogen synthase kinase 3β (GSK3β) and the E3 ubiquitin ligase F-box and WD repeat domain-containing 7α (FBW7α).
    Bialkowska AB; Liu Y; Nandan MO; Yang VW
    J Biol Chem; 2014 Feb; 289(9):5997-6005. PubMed ID: 24398687
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of GSK3β-FBXW7-JUNB axis.
    Pérez-Benavente B; Farràs R
    Oncotarget; 2013 Jul; 4(7):956-7. PubMed ID: 23918007
    [No Abstract]   [Full Text] [Related]  

  • 4. Distinct Interactions of EBP1 Isoforms with FBXW7 Elicits Different Functions in Cancer.
    Wang Y; Zhang P; Wang Y; Zhan P; Liu C; Mao JH; Wei G
    Cancer Res; 2017 Apr; 77(8):1983-1996. PubMed ID: 28209614
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
    Nakajima T; Kitagawa K; Ohhata T; Sakai S; Uchida C; Shibata K; Minegishi N; Yumimoto K; Nakayama KI; Masumoto K; Katou F; Niida H; Kitagawa M
    J Biol Chem; 2015 Apr; 290(16):10368-81. PubMed ID: 25670854
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The role of a newly identified SET domain-containing protein, SETD3, in oncogenesis.
    Chen Z; Yan CT; Dou Y; Viboolsittiseri SS; Wang JH
    Haematologica; 2013 May; 98(5):739-43. PubMed ID: 23065515
    [TBL] [Abstract][Full Text] [Related]  

  • 7. GSK3-SCF(FBXW7) targets JunB for degradation in G2 to preserve chromatid cohesion before anaphase.
    Pérez-Benavente B; García JL; Rodríguez MS; Pineda-Lucena A; Piechaczyk M; Font de Mora J; Farràs R
    Oncogene; 2013 Apr; 32(17):2189-99. PubMed ID: 22710716
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CDK5/FBW7-dependent ubiquitination and degradation of EZH2 inhibits pancreatic cancer cell migration and invasion.
    Jin X; Yang C; Fan P; Xiao J; Zhang W; Zhan S; Liu T; Wang D; Wu H
    J Biol Chem; 2017 Apr; 292(15):6269-6280. PubMed ID: 28242758
    [TBL] [Abstract][Full Text] [Related]  

  • 9. F-box and WD repeat domain-containing-7 (Fbxw7) protein targets endoplasmic reticulum-anchored osteogenic and chondrogenic transcriptional factors for degradation.
    Yumimoto K; Matsumoto M; Onoyama I; Imaizumi K; Nakayama KI
    J Biol Chem; 2013 Oct; 288(40):28488-502. PubMed ID: 23955342
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway.
    Duhamel S; Girondel C; Dorn JF; Tanguay PL; Voisin L; Smits R; Maddox PS; Meloche S
    Cell Cycle; 2016 Jun; 15(12):1631-42. PubMed ID: 27152455
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stabilization of SETD3 by deubiquitinase USP27 enhances cell proliferation and hepatocellular carcinoma progression.
    Zou T; Wang Y; Dong L; Che T; Zhao H; Yan X; Lin Z
    Cell Mol Life Sci; 2022 Jan; 79(1):70. PubMed ID: 35018513
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CK1δ/GSK3β/FBXW7α axis promotes degradation of the ZNF322A oncoprotein to suppress lung cancer progression.
    Liao SY; Chiang CW; Hsu CH; Chen YT; Jen J; Juan HF; Lai WW; Wang YC
    Oncogene; 2017 Oct; 36(41):5722-5733. PubMed ID: 28581525
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of a novel histone H3K36 methyltransferase setd3 in zebrafish.
    Kim DW; Kim KB; Kim JY; Seo SB
    Biosci Biotechnol Biochem; 2011; 75(2):289-94. PubMed ID: 21307598
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs.
    Liu N; Li H; Li S; Shen M; Xiao N; Chen Y; Wang Y; Wang W; Wang R; Wang Q; Sun J; Wang P
    J Biol Chem; 2010 Jun; 285(24):18858-67. PubMed ID: 20388706
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The emerging roles of F-box proteins in pancreatic tumorigenesis.
    Wang H; Maitra A; Wang H
    Semin Cancer Biol; 2016 Feb; 36():88-94. PubMed ID: 26384530
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation.
    Dai S; Horton JR; Wilkinson AW; Gozani O; Zhang X; Cheng X
    J Biol Chem; 2020 Feb; 295(9):2582-2589. PubMed ID: 31911441
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel mechanism by which histone deacetylase inhibitors facilitate topoisomerase IIα degradation in hepatocellular carcinoma cells.
    Chen MC; Chen CH; Chuang HC; Kulp SK; Teng CM; Chen CS
    Hepatology; 2011 Jan; 53(1):148-59. PubMed ID: 21254166
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ubiquitin Ligase, Fbw7, Targets CDX2 for Degradation via Two Phosphodegron Motifs in a GSK3β-Dependent Manner.
    Kumar Y; Shukla N; Thacker G; Kapoor I; Lochab S; Bhatt ML; Chattopadhyay N; Sanyal S; Trivedi AK
    Mol Cancer Res; 2016 Nov; 14(11):1097-1109. PubMed ID: 27470268
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tumor suppressor Fbxw7 antagonizes WNT signaling by targeting β-catenin for degradation in pancreatic cancer.
    Jiang JX; Sun CY; Tian S; Yu C; Chen MY; Zhang H
    Tumour Biol; 2016 Oct; 37(10):13893-13902. PubMed ID: 27485116
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rictor Undergoes Glycogen Synthase Kinase 3 (GSK3)-dependent, FBXW7-mediated Ubiquitination and Proteasomal Degradation.
    Koo J; Wu X; Mao Z; Khuri FR; Sun SY
    J Biol Chem; 2015 May; 290(22):14120-9. PubMed ID: 25897075
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.