These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. Orexin receptor antagonists differ from standard sleep drugs by promoting sleep at doses that do not disrupt cognition. Uslaner JM; Tye SJ; Eddins DM; Wang X; Fox SV; Savitz AT; Binns J; Cannon CE; Garson SL; Yao L; Hodgson R; Stevens J; Bowlby MR; Tannenbaum PL; Brunner J; Mcdonald TP; Gotter AL; Kuduk SD; Coleman PJ; Winrow CJ; Renger JJ Sci Transl Med; 2013 Apr; 5(179):179ra44. PubMed ID: 23552372 [TBL] [Abstract][Full Text] [Related]
6. The Discovery of Suvorexant, the First Orexin Receptor Drug for Insomnia. Coleman PJ; Gotter AL; Herring WJ; Winrow CJ; Renger JJ Annu Rev Pharmacol Toxicol; 2017 Jan; 57():509-533. PubMed ID: 27860547 [TBL] [Abstract][Full Text] [Related]
7. The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold. Gotter AL; Winrow CJ; Brunner J; Garson SL; Fox SV; Binns J; Harrell CM; Cui D; Yee KL; Stiteler M; Stevens J; Savitz A; Tannenbaum PL; Tye SJ; McDonald T; Yao L; Kuduk SD; Uslaner J; Coleman PJ; Renger JJ BMC Neurosci; 2013 Aug; 14():90. PubMed ID: 23981345 [TBL] [Abstract][Full Text] [Related]
8. The Dual Orexin Receptor Antagonist DORA-22 Improves Mild Stress-induced Sleep Disruption During the Natural Sleep Phase of Nocturnal Rats. Gamble MC; Katsuki F; McCoy JG; Strecker RE; McKenna JT Neuroscience; 2021 May; 463():30-44. PubMed ID: 33737028 [TBL] [Abstract][Full Text] [Related]
9. Orexin in sleep, addiction and more: is the perfect insomnia drug at hand? Hoyer D; Jacobson LH Neuropeptides; 2013 Dec; 47(6):477-88. PubMed ID: 24215799 [TBL] [Abstract][Full Text] [Related]
10. Dual orexin receptor antagonists - promising agents in the treatment of sleep disorders. Pałasz A; Lapray D; Peyron C; Rojczyk-Gołębiewska E; Skowronek R; Markowski G; Czajkowska B; Krzystanek M; Wiaderkiewicz R Int J Neuropsychopharmacol; 2014 Jan; 17(1):157-68. PubMed ID: 23702225 [TBL] [Abstract][Full Text] [Related]
12. Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulators. Ramirez AD; Gotter AL; Fox SV; Tannenbaum PL; Yao L; Tye SJ; McDonald T; Brunner J; Garson SL; Reiss DR; Kuduk SD; Coleman PJ; Uslaner JM; Hodgson R; Browne SE; Renger JJ; Winrow CJ Front Neurosci; 2013; 7():254. PubMed ID: 24399926 [TBL] [Abstract][Full Text] [Related]
13. Locus Coeruleus and Tuberomammillary Nuclei Ablations Attenuate Hypocretin/Orexin Antagonist-Mediated REM Sleep. Schwartz MD; Nguyen AT; Warrier DR; Palmerston JB; Thomas AM; Morairty SR; Neylan TC; Kilduff TS eNeuro; 2016; 3(2):. PubMed ID: 27022631 [TBL] [Abstract][Full Text] [Related]
14. Role of orexin-A in the ventrolateral preoptic area on components of total energy expenditure. Coborn JE; DePorter DP; Mavanji V; Sinton CM; Kotz CM; Billington CJ; Teske JA Int J Obes (Lond); 2017 Aug; 41(8):1256-1262. PubMed ID: 28392556 [TBL] [Abstract][Full Text] [Related]
16. Emerging role of orexin antagonists in insomnia therapeutics: An update on SORAs and DORAs. Kumar A; Chanana P; Choudhary S Pharmacol Rep; 2016 Apr; 68(2):231-42. PubMed ID: 26922522 [TBL] [Abstract][Full Text] [Related]
17. Orexin Receptor Antagonism Improves Sleep and Reduces Seizures in Kcna1-null Mice. Roundtree HM; Simeone TA; Johnson C; Matthews SA; Samson KK; Simeone KA Sleep; 2016 Feb; 39(2):357-68. PubMed ID: 26446112 [TBL] [Abstract][Full Text] [Related]
18. Nonclinical pharmacology of daridorexant: a new dual orexin receptor antagonist for the treatment of insomnia. Roch C; Bergamini G; Steiner MA; Clozel M Psychopharmacology (Berl); 2021 Oct; 238(10):2693-2708. PubMed ID: 34415378 [TBL] [Abstract][Full Text] [Related]
19. The 5-hydroxytryptamine4 receptor agonists prucalopride and PRX-03140 increase acetylcholine and histamine levels in the rat prefrontal cortex and the power of stimulated hippocampal θ oscillations. Johnson DE; Drummond E; Grimwood S; Sawant-Basak A; Miller E; Tseng E; McDowell LL; Vanase-Frawley MA; Fisher KE; Rubitski DM; Stutzman-Engwall KJ; Nelson RT; Horner WE; Gorczyca RR; Hajos M; Siok CJ J Pharmacol Exp Ther; 2012 Jun; 341(3):681-91. PubMed ID: 22408061 [TBL] [Abstract][Full Text] [Related]
20. An adenosine A receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats. Hong ZY; Huang ZL; Qu WM; Eguchi N; Urade Y; Hayaishi O J Neurochem; 2005 Mar; 92(6):1542-9. PubMed ID: 15748171 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]