241 related articles for article (PubMed ID: 28445472)
1. Unsuspected osteochondroma-like outgrowths in the cranial base of Hereditary Multiple Exostoses patients and modeling and treatment with a BMP antagonist in mice.
Sinha S; Mundy C; Bechtold T; Sgariglia F; Ibrahim MM; Billings PC; Carroll K; Koyama E; Jones KB; Pacifici M
PLoS Genet; 2017 Apr; 13(4):e1006742. PubMed ID: 28445472
[TBL] [Abstract][Full Text] [Related]
2. Osteochondroma formation is independent of heparanase expression as revealed in a mouse model of hereditary multiple exostoses.
Mundy C; Chung J; Koyama E; Bunting S; Mahimkar R; Pacifici M
J Orthop Res; 2022 Oct; 40(10):2391-2401. PubMed ID: 34996123
[TBL] [Abstract][Full Text] [Related]
3. The pathogenic roles of heparan sulfate deficiency in hereditary multiple exostoses.
Pacifici M
Matrix Biol; 2018 Oct; 71-72():28-39. PubMed ID: 29277722
[TBL] [Abstract][Full Text] [Related]
4. Palovarotene Inhibits Osteochondroma Formation in a Mouse Model of Multiple Hereditary Exostoses.
Inubushi T; Lemire I; Irie F; Yamaguchi Y
J Bone Miner Res; 2018 Apr; 33(4):658-666. PubMed ID: 29120519
[TBL] [Abstract][Full Text] [Related]
5. Heparan sulfate deficiency leads to hypertrophic chondrocytes by increasing bone morphogenetic protein signaling.
Kawashima K; Ogawa H; Komura S; Ishihara T; Yamaguchi Y; Akiyama H; Matsumoto K
Osteoarthritis Cartilage; 2020 Nov; 28(11):1459-1470. PubMed ID: 32818603
[TBL] [Abstract][Full Text] [Related]
6. Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: a mechanism likely deranged in Hereditary Multiple Exostoses.
Huegel J; Mundy C; Sgariglia F; Nygren P; Billings PC; Yamaguchi Y; Koyama E; Pacifici M
Dev Biol; 2013 May; 377(1):100-12. PubMed ID: 23458899
[TBL] [Abstract][Full Text] [Related]
7. Signaling systems affecting the severity of multiple osteochondromas.
Piombo V; Jochmann K; Hoffmann D; Wuelling M; Vortkamp A
Bone; 2018 Jun; 111():71-81. PubMed ID: 29545125
[TBL] [Abstract][Full Text] [Related]
8. Heparan sulfate antagonism alters bone morphogenetic protein signaling and receptor dynamics, suggesting a mechanism in hereditary multiple exostoses.
Mundy C; Yang E; Takano H; Billings PC; Pacifici M
J Biol Chem; 2018 May; 293(20):7703-7716. PubMed ID: 29622677
[TBL] [Abstract][Full Text] [Related]
9. The short-lived exostosis induced surgically versus the lasting genetic hereditary multiple exostoses.
Trebicz-Geffen M; Nevo Z; Evron Z; Posternak N; Glaser T; Fridkin M; Kollander Y; Robinson D
Exp Mol Pathol; 2003 Feb; 74(1):40-8. PubMed ID: 12645631
[TBL] [Abstract][Full Text] [Related]
10. Heparan sulfate in skeletal development, growth, and pathology: the case of hereditary multiple exostoses.
Huegel J; Sgariglia F; Enomoto-Iwamoto M; Koyama E; Dormans JP; Pacifici M
Dev Dyn; 2013 Sep; 242(9):1021-32. PubMed ID: 23821404
[TBL] [Abstract][Full Text] [Related]
11. Epiphyseal abnormalities, trabecular bone loss and articular chondrocyte hypertrophy develop in the long bones of postnatal Ext1-deficient mice.
Sgariglia F; Candela ME; Huegel J; Jacenko O; Koyama E; Yamaguchi Y; Pacifici M; Enomoto-Iwamoto M
Bone; 2013 Nov; 57(1):220-31. PubMed ID: 23958822
[TBL] [Abstract][Full Text] [Related]
12. A mouse model of chondrocyte-specific somatic mutation reveals a role for Ext1 loss of heterozygosity in multiple hereditary exostoses.
Matsumoto K; Irie F; Mackem S; Yamaguchi Y
Proc Natl Acad Sci U S A; 2010 Jun; 107(24):10932-7. PubMed ID: 20534475
[TBL] [Abstract][Full Text] [Related]
13. Heparanase stimulates chondrogenesis and is up-regulated in human ectopic cartilage: a mechanism possibly involved in hereditary multiple exostoses.
Huegel J; Enomoto-Iwamoto M; Sgariglia F; Koyama E; Pacifici M
Am J Pathol; 2015 Jun; 185(6):1676-85. PubMed ID: 25863260
[TBL] [Abstract][Full Text] [Related]
14. Compound heterozygous loss of Ext1 and Ext2 is sufficient for formation of multiple exostoses in mouse ribs and long bones.
Zak BM; Schuksz M; Koyama E; Mundy C; Wells DE; Yamaguchi Y; Pacifici M; Esko JD
Bone; 2011 May; 48(5):979-87. PubMed ID: 21310272
[TBL] [Abstract][Full Text] [Related]
15. Hereditary Multiple Exostoses: New Insights into Pathogenesis, Clinical Complications, and Potential Treatments.
Pacifici M
Curr Osteoporos Rep; 2017 Jun; 15(3):142-152. PubMed ID: 28466453
[TBL] [Abstract][Full Text] [Related]
16. Dysplasia epiphysealis hemimelica (Trevor disease): a rare developmental disorder of bone mimicking osteochondroma of long bones.
Glick R; Khaldi L; Ptaszynski K; Steiner GC
Hum Pathol; 2007 Aug; 38(8):1265-72. PubMed ID: 17490719
[TBL] [Abstract][Full Text] [Related]
17. No haploinsufficiency but loss of heterozygosity for EXT in multiple osteochondromas.
Reijnders CM; Waaijer CJ; Hamilton A; Buddingh EP; Dijkstra SP; Ham J; Bakker E; Szuhai K; Karperien M; Hogendoorn PC; Stringer SE; Bovée JV
Am J Pathol; 2010 Oct; 177(4):1946-57. PubMed ID: 20813973
[TBL] [Abstract][Full Text] [Related]
18. The type 2 diabetes associated rs7903146 T allele within TCF7L2 is significantly under-represented in Hereditary Multiple Exostoses: insights into pathogenesis.
Sgariglia F; Pedrini E; Bradfield JP; Bhatti TR; D'Adamo P; Dormans JP; Gunawardena AT; Hakonarson H; Hecht JT; Sangiorgi L; Pacifici M; Enomoto-Iwamoto M; Grant SF
Bone; 2015 Mar; 72():123-7. PubMed ID: 25498973
[TBL] [Abstract][Full Text] [Related]
19. Heparan sulfate as a regulator of endochondral ossification and osteochondroma development.
Jochmann K; Bachvarova V; Vortkamp A
Matrix Biol; 2014 Feb; 34():55-63. PubMed ID: 24370655
[TBL] [Abstract][Full Text] [Related]
20. Transgenic expression of the EXT2 gene in developing chondrocytes enhances the synthesis of heparan sulfate and bone formation in mice.
Morimoto K; Shimizu T; Furukawa K; Morio H; Kurosawa H; Shirasawa T
Biochem Biophys Res Commun; 2002 Apr; 292(4):999-1009. PubMed ID: 11944914
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
