These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
348 related articles for article (PubMed ID: 28446642)
1. Cotargeting mTORC and EGFR Signaling as a Therapeutic Strategy in HNSCC. Swick AD; Prabakaran PJ; Miller MC; Javaid AM; Fisher MM; Sampene E; Ong IM; Hu R; Iida M; Nickel KP; Bruce JY; Wheeler DL; Kimple RJ Mol Cancer Ther; 2017 Jul; 16(7):1257-1268. PubMed ID: 28446642 [TBL] [Abstract][Full Text] [Related]
2. mTOR co-targeting in cetuximab resistance in head and neck cancers harboring PIK3CA and RAS mutations. Wang Z; Martin D; Molinolo AA; Patel V; Iglesias-Bartolome R; Degese MS; Vitale-Cross L; Chen Q; Gutkind JS J Natl Cancer Inst; 2014 Sep; 106(9):. PubMed ID: 25099740 [TBL] [Abstract][Full Text] [Related]
3. A controlled trial of HNSCC patient-derived xenografts reveals broad efficacy of PI3Kα inhibition in controlling tumor growth. Ruicci KM; Meens J; Sun RX; Rizzo G; Pinto N; Yoo J; Fung K; MacNeil D; Mymryk JS; Barrett JW; Boutros PC; Ailles L; Nichols AC Int J Cancer; 2019 Oct; 145(8):2100-2106. PubMed ID: 30468243 [TBL] [Abstract][Full Text] [Related]
4. HER3 Targeting Sensitizes HNSCC to Cetuximab by Reducing HER3 Activity and HER2/HER3 Dimerization: Evidence from Cell Line and Patient-Derived Xenograft Models. Wang D; Qian G; Zhang H; Magliocca KR; Nannapaneni S; Amin AR; Rossi M; Patel M; El-Deiry M; Wadsworth JT; Chen Z; Khuri FR; Shin DM; Saba NF; Chen ZG Clin Cancer Res; 2017 Feb; 23(3):677-686. PubMed ID: 27358485 [TBL] [Abstract][Full Text] [Related]
5. Lymphotoxin-β Interacts with Methylated EGFR to Mediate Acquired Resistance to Cetuximab in Head and Neck Cancer. Hsu DS; Hwang WL; Yuh CH; Chu CH; Ho YH; Chen PB; Lin HS; Lin HK; Wu SP; Lin CY; Hsu WH; Lan HY; Wang HJ; Tai SK; Hung MC; Yang MH Clin Cancer Res; 2017 Aug; 23(15):4388-4401. PubMed ID: 28196873 [No Abstract] [Full Text] [Related]
7. A positive feedback loop involving EGFR/Akt/mTORC1 and IKK/NF-kB regulates head and neck squamous cell carcinoma proliferation. Li Z; Yang Z; Passaniti A; Lapidus RG; Liu X; Cullen KJ; Dan HC Oncotarget; 2016 May; 7(22):31892-906. PubMed ID: 26895469 [TBL] [Abstract][Full Text] [Related]
8. The PI3K/Akt/mTORC signaling axis in head and neck squamous cell carcinoma: Possibilities for therapeutic interventions either as single agents or in combination with conventional therapies. Akbari Dilmaghani N; Safaroghli-Azar A; Pourbagheri-Sigaroodi A; Bashash D IUBMB Life; 2021 Apr; 73(4):618-642. PubMed ID: 33476088 [TBL] [Abstract][Full Text] [Related]
9. Combination of phosphotidylinositol-3-kinase targeting with cetuximab and irradiation: A preclinical study on an orthotopic xenograft model of head and neck cancer. Bozec A; Ebran N; Radosevic-Robin N; Chamorey E; Yahia HB; Marcie S; Gautier M; Penault-Llorca F; Milano G Head Neck; 2017 Jan; 39(1):151-159. PubMed ID: 27507562 [TBL] [Abstract][Full Text] [Related]
10. CCI-779 (Temsirolimus) exhibits increased anti-tumor activity in low EGFR expressing HNSCC cell lines and is effective in cells with acquired resistance to cisplatin or cetuximab. Niehr F; Weichert W; Stenzinger A; Budach V; Tinhofer I J Transl Med; 2015 Apr; 13():106. PubMed ID: 25890004 [TBL] [Abstract][Full Text] [Related]
11. ERK-dependent IL-6 autocrine signaling mediates adaptive resistance to pan-PI3K inhibitor BKM120 in head and neck squamous cell carcinoma. Yun MR; Choi HM; Kang HN; Lee Y; Joo HS; Kim DH; Kim HR; Hong MH; Yoon SO; Cho BC Oncogene; 2018 Jan; 37(3):377-388. PubMed ID: 28945228 [TBL] [Abstract][Full Text] [Related]
12. Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer. Keysar SB; Le PN; Anderson RT; Morton JJ; Bowles DW; Paylor JJ; Vogler BW; Thorburn J; Fernandez P; Glogowska MJ; Takimoto SM; Sehrt DB; Gan GN; Eagles-Soukup JR; Serracino H; Hirsch FR; Lucia MS; Thorburn A; Song JI; Wang XJ; Jimeno A Cancer Res; 2013 Jun; 73(11):3381-92. PubMed ID: 23576557 [TBL] [Abstract][Full Text] [Related]
13. Elevated RET expression enhances EGFR activation and mediates EGFR inhibitor resistance in head and neck squamous cell carcinoma. Lin C; Lu W; Ren Z; Tang Y; Zhang C; Yang R; Chen Y; Cao W; Wang L; Wang X; Ji T Cancer Lett; 2016 Jul; 377(1):1-10. PubMed ID: 27090738 [TBL] [Abstract][Full Text] [Related]
14. Schedule-dependent interaction between temsirolimus and cetuximab in head and neck cancer: a preclinical study. Lattanzio L; Milano G; Monteverde M; Tonissi F; Vivenza D; Merlano M; Lo Nigro C Anticancer Drugs; 2016 Jul; 27(6):533-9. PubMed ID: 26982238 [TBL] [Abstract][Full Text] [Related]
15. Biomarkers of cetuximab resistance in patients with head and neck squamous cell carcinoma. Leblanc O; Vacher S; Lecerf C; Jeannot E; Klijanienko J; Berger F; Hoffmann C; Calugaru V; Badois N; Chilles A; Lesnik M; Krhili S; Bieche I; Le Tourneau C; Kamal M Cancer Biol Med; 2020 Feb; 17(1):208-217. PubMed ID: 32296588 [No Abstract] [Full Text] [Related]
16. Dacomitinib, an irreversible Pan-ErbB inhibitor significantly abrogates growth in head and neck cancer models that exhibit low response to cetuximab. Ather F; Hamidi H; Fejzo MS; Letrent S; Finn RS; Kabbinavar F; Head C; Wong SG PLoS One; 2013; 8(2):e56112. PubMed ID: 23405260 [TBL] [Abstract][Full Text] [Related]
17. The dual PI3K/mTOR inhibitor PKI-587 enhances sensitivity to cetuximab in EGFR-resistant human head and neck cancer models. D'Amato V; Rosa R; D'Amato C; Formisano L; Marciano R; Nappi L; Raimondo L; Di Mauro C; Servetto A; Fusciello C; Veneziani BM; De Placido S; Bianco R Br J Cancer; 2014 Jun; 110(12):2887-95. PubMed ID: 24823695 [TBL] [Abstract][Full Text] [Related]
18. Preclinical modeling of EGFR inhibitor resistance in head and neck cancer. Quesnelle KM; Wheeler SE; Ratay MK; Grandis JR Cancer Biol Ther; 2012 Aug; 13(10):935-45. PubMed ID: 22785204 [TBL] [Abstract][Full Text] [Related]
19. EGFR Alterations Influence the Cetuximab Treatment Response and c-MET Tyrosine-Kinase Inhibitor Sensitivity in Experimental Head and Neck Squamous Cell Carcinomas. Nelhűbel GA; Cserepes M; Szabó B; Türk D; Kárpáti A; Kenessey I; Rásó E; Barbai T; Hegedűs Z; László V; Szokol B; Dobos J; Őrfi L; Tóvári J Pathol Oncol Res; 2021; 27():620256. PubMed ID: 34257586 [No Abstract] [Full Text] [Related]
20. Mechanisms underlying resistance to cetuximab in the HNSCC cell line: role of AKT inhibition in bypassing this resistance. Rebucci M; Peixoto P; Dewitte A; Wattez N; De Nuncques MA; Rezvoy N; Vautravers-Dewas C; Buisine MP; Guerin E; Peyrat JP; Lartigau E; Lansiaux A Int J Oncol; 2011 Jan; 38(1):189-200. PubMed ID: 21109940 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]