BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

218 related articles for article (PubMed ID: 28452363)

  • 1. Mechanism of SOS PR-domain autoinhibition revealed by single-molecule assays on native protein from lysate.
    Lee YK; Low-Nam ST; Chung JK; Hansen SD; Lam HYM; Alvarez S; Groves JT
    Nat Commun; 2017 Apr; 8():15061. PubMed ID: 28452363
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Membrane-dependent signal integration by the Ras activator Son of sevenless.
    Gureasko J; Galush WJ; Boykevisch S; Sondermann H; Bar-Sagi D; Groves JT; Kuriyan J
    Nat Struct Mol Biol; 2008 May; 15(5):452-61. PubMed ID: 18454158
    [TBL] [Abstract][Full Text] [Related]  

  • 3. High-Affinity Interactions of the nSH3/cSH3 Domains of Grb2 with the C-Terminal Proline-Rich Domain of SOS1.
    Liao TJ; Jang H; Nussinov R; Fushman D
    J Am Chem Soc; 2020 Feb; 142(7):3401-3411. PubMed ID: 31970984
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phospholipase D2-generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos.
    Zhao C; Du G; Skowronek K; Frohman MA; Bar-Sagi D
    Nat Cell Biol; 2007 Jun; 9(6):706-12. PubMed ID: 17486115
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Ras-induced conformational switch in the Ras activator Son of sevenless.
    Freedman TS; Sondermann H; Friedland GD; Kortemme T; Bar-Sagi D; Marqusee S; Kuriyan J
    Proc Natl Acad Sci U S A; 2006 Nov; 103(45):16692-7. PubMed ID: 17075039
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural basis of the differential binding of the SH3 domains of Grb2 adaptor to the guanine nucleotide exchange factor Sos1.
    McDonald CB; Seldeen KL; Deegan BJ; Farooq A
    Arch Biochem Biophys; 2008 Nov; 479(1):52-62. PubMed ID: 18778683
    [TBL] [Abstract][Full Text] [Related]  

  • 7. One-way membrane trafficking of SOS in receptor-triggered Ras activation.
    Christensen SM; Tu HL; Jun JE; Alvarez S; Triplet MG; Iwig JS; Yadav KK; Bar-Sagi D; Roose JP; Groves JT
    Nat Struct Mol Biol; 2016 Sep; 23(9):838-46. PubMed ID: 27501536
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanisms through which Sos-1 coordinates the activation of Ras and Rac.
    Innocenti M; Tenca P; Frittoli E; Faretta M; Tocchetti A; Di Fiore PP; Scita G
    J Cell Biol; 2002 Jan; 156(1):125-36. PubMed ID: 11777939
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS.
    Huang WYC; Alvarez S; Kondo Y; Lee YK; Chung JK; Lam HYM; Biswas KH; Kuriyan J; Groves JT
    Science; 2019 Mar; 363(6431):1098-1103. PubMed ID: 30846600
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Interdependent Activation of Son-of-Sevenless and Ras.
    Bandaru P; Kondo Y; Kuriyan J
    Cold Spring Harb Perspect Med; 2019 Feb; 9(2):. PubMed ID: 29610148
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The intramolecular allostery of GRB2 governing its interaction with SOS1 is modulated by phosphotyrosine ligands.
    Kazemein Jasemi NS; Herrmann C; Magdalena Estirado E; Gremer L; Willbold D; Brunsveld L; Dvorsky R; Ahmadian MR
    Biochem J; 2021 Jul; 478(14):2793-2809. PubMed ID: 34232285
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sos-mediated activation of rac1 by p66shc.
    Khanday FA; Santhanam L; Kasuno K; Yamamori T; Naqvi A; Dericco J; Bugayenko A; Mattagajasingh I; Disanza A; Scita G; Irani K
    J Cell Biol; 2006 Mar; 172(6):817-22. PubMed ID: 16520382
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Allosteric gating of Son of sevenless activity by the histone domain.
    Yadav KK; Bar-Sagi D
    Proc Natl Acad Sci U S A; 2010 Feb; 107(8):3436-40. PubMed ID: 20133694
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes.
    Roose JP; Mollenauer M; Ho M; Kurosaki T; Weiss A
    Mol Cell Biol; 2007 Apr; 27(7):2732-45. PubMed ID: 17283063
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SOS1 interacts with Grb2 through regions that induce closed nSH3 conformations.
    Liao TJ; Jang H; Fushman D; Nussinov R
    J Chem Phys; 2020 Jul; 153(4):045106. PubMed ID: 32752665
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless.
    Gureasko J; Kuchment O; Makino DL; Sondermann H; Bar-Sagi D; Kuriyan J
    Proc Natl Acad Sci U S A; 2010 Feb; 107(8):3430-5. PubMed ID: 20133692
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Allosteric KRas4B Can Modulate SOS1 Fast and Slow Ras Activation Cycles.
    Liao TJ; Jang H; Fushman D; Nussinov R
    Biophys J; 2018 Aug; 115(4):629-641. PubMed ID: 30097175
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Assembly of the Sos1-Grb2-Gab1 ternary signaling complex is under allosteric control.
    McDonald CB; Seldeen KL; Deegan BJ; Bhat V; Farooq A
    Arch Biochem Biophys; 2010 Feb; 494(2):216-25. PubMed ID: 20005866
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural analysis of autoinhibition in the Ras activator Son of sevenless.
    Sondermann H; Soisson SM; Boykevisch S; Yang SS; Bar-Sagi D; Kuriyan J
    Cell; 2004 Oct; 119(3):393-405. PubMed ID: 15507210
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Quantifying intramolecular binding in multivalent interactions: a structure-based synergistic study on Grb2-Sos1 complex.
    Sethi A; Goldstein B; Gnanakaran S
    PLoS Comput Biol; 2011 Oct; 7(10):e1002192. PubMed ID: 22022247
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.