These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 28455968)

  • 1. Dishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma.
    Tsui YM; Sze KM; Tung EK; Ho DW; Lee TK; Ng IO
    Oncotarget; 2017 Jun; 8(24):39430-39442. PubMed ID: 28455968
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cripto-1 contributes to stemness in hepatocellular carcinoma by stabilizing Dishevelled-3 and activating Wnt/β-catenin pathway.
    Lo RC; Leung CO; Chan KK; Ho DW; Wong CM; Lee TK; Ng IO
    Cell Death Differ; 2018 Aug; 25(8):1426-1441. PubMed ID: 29445127
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Prickle-1 negatively regulates Wnt/beta-catenin pathway by promoting Dishevelled ubiquitination/degradation in liver cancer.
    Chan DW; Chan CY; Yam JW; Ching YP; Ng IO
    Gastroenterology; 2006 Oct; 131(4):1218-27. PubMed ID: 17030191
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lysine-specific demethylase 1 promotes the stemness and chemoresistance of Lgr5(+) liver cancer initiating cells by suppressing negative regulators of β-catenin signaling.
    Lei ZJ; Wang J; Xiao HL; Guo Y; Wang T; Li Q; Liu L; Luo X; Fan LL; Lin L; Mao CY; Wang SN; Wei YL; Lan CH; Jiang J; Yang XJ; Liu PD; Chen DF; Wang B
    Oncogene; 2015 Jun; 34(24):3188-98. PubMed ID: 25893304
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hipk2 and PP1c cooperate to maintain Dvl protein levels required for Wnt signal transduction.
    Shimizu N; Ishitani S; Sato A; Shibuya H; Ishitani T
    Cell Rep; 2014 Sep; 8(5):1391-404. PubMed ID: 25159144
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The ubiquitin ligase TRIM25 inhibits hepatocellular carcinoma progression by targeting metastasis associated 1 protein.
    Zang HL; Ren SN; Cao H; Tian XF
    IUBMB Life; 2017 Oct; 69(10):795-801. PubMed ID: 28861931
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LGR5/R-Spo1/Wnt3a axis promotes stemness and aggressive phenotype in hepatoblast-like hepatocellular carcinoma cell lines.
    Akbari S; Kunter I; Azbazdar Y; Ozhan G; Atabey N; Firtina Karagonlar Z; Erdal E
    Cell Signal; 2021 Jun; 82():109972. PubMed ID: 33684507
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HIPK2 suppresses tumor growth and progression of hepatocellular carcinoma through promoting the degradation of HIF-1α.
    Chen P; Duan X; Li X; Li J; Ba Q; Wang H
    Oncogene; 2020 Apr; 39(14):2863-2876. PubMed ID: 32034309
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Osteopontin promotes a cancer stem cell-like phenotype in hepatocellular carcinoma cells via an integrin-NF-κB-HIF-1α pathway.
    Cao L; Fan X; Jing W; Liang Y; Chen R; Liu Y; Zhu M; Jia R; Wang H; Zhang X; Zhang Y; Zhou X; Zhao J; Guo Y
    Oncotarget; 2015 Mar; 6(9):6627-40. PubMed ID: 25749383
    [TBL] [Abstract][Full Text] [Related]  

  • 10. HECT (Homologous to the E6-AP Carboxyl Terminus)-Type Ubiquitin E3 Ligase ITCH Attenuates Cardiac Hypertrophy by Suppressing the Wnt/β-Catenin Signaling Pathway.
    Goto J; Otaki Y; Watanabe T; Kobayashi Y; Aono T; Watanabe K; Wanezaki M; Kutsuzawa D; Kato S; Tamura H; Nishiyama S; Arimoto T; Takahashi H; Shishido T; Watanabe M
    Hypertension; 2020 Dec; 76(6):1868-1878. PubMed ID: 33131309
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphorylation-dependent control of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2.
    Roscic A; Möller A; Calzado MA; Renner F; Wimmer VC; Gresko E; Lüdi KS; Schmitz ML
    Mol Cell; 2006 Oct; 24(1):77-89. PubMed ID: 17018294
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dishevelled 1-Regulated Superpotent Cancer Stem Cells Mediate Wnt Heterogeneity and Tumor Progression in Hepatocellular Carcinoma.
    Liao WY; Hsu CC; Chan TS; Yen CJ; Chen WY; Pan HW; Tsai KK
    Stem Cell Reports; 2020 Mar; 14(3):462-477. PubMed ID: 32160521
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hypoxia suppresses chemotherapeutic drug-induced p53 Serine 46 phosphorylation by triggering HIPK2 degradation.
    Moehlenbrink J; Bitomsky N; Hofmann TG
    Cancer Lett; 2010 Jun; 292(1):119-24. PubMed ID: 20018442
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Y-box binding protein-1 promotes hepatocellular carcinoma-initiating cell progression and tumorigenesis via Wnt/β-catenin pathway.
    Chao HM; Huang HX; Chang PH; Tseng KC; Miyajima A; Chern E
    Oncotarget; 2017 Jan; 8(2):2604-2616. PubMed ID: 27911878
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Homeodomain-interacting protein kinase 2 (HIPK2) targets beta-catenin for phosphorylation and proteasomal degradation.
    Kim EA; Kim JE; Sung KS; Choi DW; Lee BJ; Choi CY
    Biochem Biophys Res Commun; 2010 Apr; 394(4):966-71. PubMed ID: 20307497
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HIPK2 regulates transforming growth factor-beta-induced c-Jun NH(2)-terminal kinase activation and apoptosis in human hepatoma cells.
    Hofmann TG; Stollberg N; Schmitz ML; Will H
    Cancer Res; 2003 Dec; 63(23):8271-7. PubMed ID: 14678985
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Systematic summarization of the expression profiles and prognostic roles of the dishevelled gene family in hepatocellular carcinoma.
    Mei J; Yang X; Xia D; Zhou W; Gu D; Wang H; Liu C
    Mol Genet Genomic Med; 2020 Sep; 8(9):e1384. PubMed ID: 32588988
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputs.
    Hanáková K; Bernatík O; Kravec M; Micka M; Kumar J; Harnoš J; Ovesná P; Paclíková P; Rádsetoulal M; Potěšil D; Tripsianes K; Čajánek L; Zdráhal Z; Bryja V
    Cell Commun Signal; 2019 Dec; 17(1):170. PubMed ID: 31870452
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Androgen/androgen receptor axis maintains and promotes cancer cell stemness through direct activation of Nanog transcription in hepatocellular carcinoma.
    Jiang L; Shan J; Shen J; Wang Y; Yan P; Liu L; Zhao W; Xu Y; Zhu W; Su L; Chen J; Cheng F; Yao H; Xu H; Qian C; Liang Z
    Oncotarget; 2016 Jun; 7(24):36814-36828. PubMed ID: 27167111
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stabilization of HIPK2 by escape from proteasomal degradation mediated by the E3 ubiquitin ligase Siah1.
    Kim SY; Choi DW; Kim EA; Choi CY
    Cancer Lett; 2009 Jul; 279(2):177-84. PubMed ID: 19250734
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.