These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

378 related articles for article (PubMed ID: 28455970)

  • 1. Mitochondrial replacement in an iPSC model of Leber's hereditary optic neuropathy.
    Wong RCB; Lim SY; Hung SSC; Jackson S; Khan S; Van Bergen NJ; De Smit E; Liang HH; Kearns LS; Clarke L; Mackey DA; Hewitt AW; Trounce IA; Pébay A
    Aging (Albany NY); 2017 Apr; 9(4):1341-1350. PubMed ID: 28455970
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nuclear modifier YARS2 allele correction restored retinal ganglion cells-specific deficiencies in Leber's hereditary optic neuropathy.
    Chen JR; Chen C; Chen J; Ji Y; Lian Y; Zhang J; Yu J; Li XY; Qu J; Guan MX
    Hum Mol Genet; 2023 Apr; 32(9):1539-1551. PubMed ID: 36611011
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bioactivity and gene expression profiles of hiPSC-generated retinal ganglion cells in MT-ND4 mutated Leber's hereditary optic neuropathy.
    Wu YR; Wang AG; Chen YT; Yarmishyn AA; Buddhakosai W; Yang TC; Hwang DK; Yang YP; Shen CN; Lee HC; Chiou SH; Peng CH; Chen SJ
    Exp Cell Res; 2018 Feb; 363(2):299-309. PubMed ID: 29366807
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Creating Cell Model 2.0 Using Patient Samples Carrying a Pathogenic Mitochondrial DNA Mutation: iPSC Approach for LHON.
    Singh P; Bahr T; Zhao X; Hu P; Daadi M; Huang T; Bai Y
    Methods Mol Biol; 2022; 2549():219-231. PubMed ID: 34669166
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of angiogenesis by the secretome from iPSC-derived retinal ganglion cells with Leber's hereditary optic neuropathy-like phenotypes.
    Peng SY; Chen CY; Chen H; Yang YP; Wang ML; Tsai FT; Chien CS; Weng PY; Tsai ET; Wang IC; Hsu CC; Lin TC; Hwang DK; Chen SJ; Chiou SH; Chiao CC; Chien Y
    Biomed Pharmacother; 2024 Sep; 178():117270. PubMed ID: 39126773
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Emerging model systems and treatment approaches for Leber's hereditary optic neuropathy: Challenges and opportunities.
    Bahr T; Welburn K; Donnelly J; Bai Y
    Biochim Biophys Acta Mol Basis Dis; 2020 Jun; 1866(6):165743. PubMed ID: 32105823
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Generation of patient-specific induced pluripotent stem cells from Leber's hereditary optic neuropathy.
    Lu HE; Yang YP; Chen YT; Wu YR; Wang CL; Tsai FT; Hwang DK; Lin TC; Chen SJ; Wang AG; Hsieh PCH; Chiou SH
    Stem Cell Res; 2018 Apr; 28():56-60. PubMed ID: 29427840
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Leber's Hereditary Optic Neuropathy as a Promising Disease for Gene Therapy Development.
    Karaarslan C
    Adv Ther; 2019 Dec; 36(12):3299-3307. PubMed ID: 31605306
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Generation of a human iPSC line, FINCBi001-A, carrying a homoplasmic m.G3460A mutation in MT-ND1 associated with Leber's Hereditary optic Neuropathy (LHON).
    Peron C; Mauceri R; Cabassi T; Segnali A; Maresca A; Iannielli A; Rizzo A; Sciacca FL; Broccoli V; Carelli V; Tiranti V
    Stem Cell Res; 2020 Oct; 48():101939. PubMed ID: 32771908
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mitochondrial transport mediates survival of retinal ganglion cells in affected LHON patients.
    Yang TC; Yarmishyn AA; Yang YP; Lu PC; Chou SJ; Wang ML; Lin TC; Hwang DK; Chou YB; Chen SJ; Yu WK; Wang AG; Hsu CC; Chiou SH
    Hum Mol Genet; 2020 Jun; 29(9):1454-1464. PubMed ID: 32277753
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Abnormal morphology and function in retinal ganglion cells derived from patients-specific iPSCs generated from individuals with Leber's hereditary optic neuropathy.
    Nie Z; Wang C; Chen J; Ji Y; Zhang H; Zhao F; Zhou X; Guan MX
    Hum Mol Genet; 2023 Jan; 32(2):231-243. PubMed ID: 35947995
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Generation of an induced pluripotent stem cell line from a patient with leber's hereditary optic neuropathy carrying a homoplasmic m.3635G > A mutation in the mitochondrial ND1 gene.
    Ji D; Su X; Hu C; Zhang Z; Wang M; Zou W; Shen L; Liu Y; Liang C; Du Y; Liang D; Cao Y
    Stem Cell Res; 2022 Aug; 63():102858. PubMed ID: 35905669
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Glutamate Stimulation Dysregulates AMPA Receptors-Induced Signal Transduction Pathway in Leber's Inherited Optic Neuropathy Patient-Specific hiPSC-Derived Retinal Ganglion Cells.
    Yang YP; Nguyen PNN; Lin TC; Yarmishyn AA; Chen WS; Hwang DK; Chiou GY; Lin TW; Chien CS; Tsai CY; Chiou SH; Chen SJ; Peng CH; Hsu CC
    Cells; 2019 Jun; 8(6):. PubMed ID: 31234430
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HLA-Homozygous iPSC-Derived Mesenchymal Stem Cells Rescue Rotenone-Induced Experimental Leber's Hereditary Optic Neuropathy-like Models In Vitro and In Vivo.
    Tsai ET; Peng SY; Wu YR; Lin TC; Chen CY; Liu YH; Tseng YH; Hsiao YJ; Tseng HC; Lai WY; Lin YY; Yang YP; Chiou SH; Chen SP; Chien Y
    Cells; 2023 Nov; 12(22):. PubMed ID: 37998352
    [TBL] [Abstract][Full Text] [Related]  

  • 15. LHON gene therapy vector prevents visual loss and optic neuropathy induced by G11778A mutant mitochondrial DNA: biodistribution and toxicology profile.
    Koilkonda R; Yu H; Talla V; Porciatti V; Feuer WJ; Hauswirth WW; Chiodo V; Erger KE; Boye SL; Lewin AS; Conlon TJ; Renner L; Neuringer M; Detrisac C; Guy J
    Invest Ophthalmol Vis Sci; 2014 Oct; 55(12):7739-53. PubMed ID: 25342621
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Three Cases of Leber's Hereditary Optic Neuropathy with Rapid Increase in Visual Acuity After Gene Therapy.
    Zhang Y; Yuan JJ; Liu HL; Tian Z; Liu SW; Li B
    Curr Gene Ther; 2019; 19(2):134-138. PubMed ID: 31237206
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pathologically Responsive Mitochondrial Gene Therapy in an Allotopic Expression-Independent Manner Cures Leber's Hereditary Optic Neuropathy.
    Wang Y; Hu LF; Cui PF; Qi LY; Xing L; Jiang HL
    Adv Mater; 2021 Oct; 33(41):e2103307. PubMed ID: 34431574
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The pathological mechanisms and novel therapeutics for Leber's hereditary optic neuropathy.
    Yang YP; Foustine S; Hsiao YJ; Tsai ET; Tsai FT; Wang CL; Ko YL; Tai HY; Tsai YC; Yang CH; Fu YJ; Wang AG; Chien Y
    J Chin Med Assoc; 2023 Jun; 86(6):539-541. PubMed ID: 37027535
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Clinical research progress of gene therapy for Leber hereditary optic neuropathy].
    Wu YJ; Li WS
    Zhonghua Yan Ke Za Zhi; 2018 Aug; 54(8):636-640. PubMed ID: 30107658
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pathophysiology of Conversion to Symptomatic Leber Hereditary Optic Neuropathy and Therapeutic Implications: a Review.
    Mejia-Vergara AJ; Seleme N; Sadun AA; Karanjia R
    Curr Neurol Neurosci Rep; 2020 Apr; 20(5):11. PubMed ID: 32296973
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.