These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 28458134)

  • 1. Design, synthesis, and identification of a novel napthalamide-isoselenocyanate compound NISC-6 as a dual Topoisomerase-IIα and Akt pathway inhibitor, and evaluation of its anti-melanoma activity.
    Karelia DN; Sk UH; Singh P; Gowda ASP; Pandey MK; Ramisetti SR; Amin S; Sharma AK
    Eur J Med Chem; 2017 Jul; 135():282-295. PubMed ID: 28458134
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, topoisomerase I & II inhibitory activity, antiproliferative activity, and structure-activity relationship study of pyrazoline derivatives: An ATP-competitive human topoisomerase IIα catalytic inhibitor.
    Ahmad P; Woo H; Jun KY; Kadi AA; Abdel-Aziz HA; Kwon Y; Rahman AF
    Bioorg Med Chem; 2016 Apr; 24(8):1898-908. PubMed ID: 26988802
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A cysteine-reactive alkyl hydroquinone modifies topoisomerase IIα, enhances DNA breakage, and induces apoptosis in cancer cells.
    Lin TY; Huang CP; Au LC; Chang YW; Hu CY; Lin SB
    Chem Res Toxicol; 2012 Nov; 25(11):2340-51. PubMed ID: 23088786
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and their salts as potent cytotoxic agents and topoisomerase I/IIα inhibitors.
    Arepalli SK; Lee C; Sim S; Lee K; Jo H; Jun KY; Kwon Y; Kang JS; Jung JK; Lee H
    Bioorg Med Chem; 2018 Oct; 26(18):5181-5193. PubMed ID: 30253887
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and synthesis of 2-phenylnaphthalenoids as inhibitors of DNA topoisomeraseIIα and antitumor agents.
    Chen W; Shen Y; Li Z; Zhang M; Lu C; Shen Y
    Eur J Med Chem; 2014 Oct; 86():782-96. PubMed ID: 25240702
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of imidazopyridinyl-1,3,4-oxadiazole conjugates as apoptosis inducers and topoisomerase IIα inhibitors.
    Subba Rao AV; Vishnu Vardhan MV; Subba Reddy NV; Srinivasa Reddy T; Shaik SP; Bagul C; Kamal A
    Bioorg Chem; 2016 Dec; 69():7-19. PubMed ID: 27656775
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hydroxylated 2,4-diphenyl indenopyridine derivatives as a selective non-intercalative topoisomerase IIα catalytic inhibitor.
    Kadayat TM; Park C; Jun KY; Thapa Magar TB; Bist G; Yoo HY; Kwon Y; Lee ES
    Eur J Med Chem; 2015 Jan; 90():302-14. PubMed ID: 25437617
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 3-(3-Butylamino-2-hydroxy-propoxy)-1-hydroxy-xanthen-9-one acts as a topoisomerase IIα catalytic inhibitor with low DNA damage.
    Park SE; Chang IH; Jun KY; Lee E; Lee ES; Na Y; Kwon Y
    Eur J Med Chem; 2013 Nov; 69():139-45. PubMed ID: 24013413
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, biological evaluation, and molecular docking study of 3-(3'-heteroatom substituted-2'-hydroxy-1'-propyloxy) xanthone analogues as novel topoisomerase IIα catalytic inhibitor.
    Jun KY; Lee EY; Jung MJ; Lee OH; Lee ES; Park Choo HY; Na Y; Kwon Y
    Eur J Med Chem; 2011 Jun; 46(6):1964-71. PubMed ID: 21419530
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis, cytotoxicity, HuTopoIIα inhibitory activity and molecular docking studies of pyrazole derivatives as potential anticancer agents.
    Alam R; Wahi D; Singh R; Sinha D; Tandon V; Grover A; Rahisuddin
    Bioorg Chem; 2016 Dec; 69():77-90. PubMed ID: 27744115
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A new phenolic series of indenopyridinone as topoisomerase inhibitors: Design, synthesis, and structure-activity relationships.
    Shrestha A; Park S; Jang HJ; Katila P; Shrestha R; Kwon Y; Lee ES
    Bioorg Med Chem; 2018 Oct; 26(18):5212-5223. PubMed ID: 30262132
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, biological evaluation and modeling studies of terphenyl topoisomerase IIα inhibitors as anticancer agents.
    Qiu J; Zhao B; Zhong W; Shen Y; Lin H
    Eur J Med Chem; 2015 Apr; 94():427-35. PubMed ID: 25800514
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis of rotenoid derivatives with cytotoxic and topoisomerase II inhibitory activities.
    Sangthong S; Krusong K; Ngamrojanavanich N; Vilaivan T; Puthong S; Chandchawan S; Muangsin N
    Bioorg Med Chem Lett; 2011 Aug; 21(16):4813-8. PubMed ID: 21741833
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of novel C4-benzazole naphthalimide derivatives with potent anti-tumor properties against murine melanoma.
    Lu YT; Chen TL; Chang KS; Chang CM; Wei TY; Liu JW; Hsiao CA; Shih TL
    Bioorg Med Chem; 2017 Jan; 25(2):789-794. PubMed ID: 27939348
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design and synthesis of novel thiobarbituric acid derivatives targeting both wild-type and BRAF-mutated melanoma cells.
    Ramisetti SR; Pandey MK; Lee SY; Karelia D; Narayan S; Amin S; Sharma AK
    Eur J Med Chem; 2018 Jan; 143():1919-1930. PubMed ID: 29133035
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Thiosemicarbazones and 4-thiazolidinones indole-based derivatives: Synthesis, evaluation of antiproliferative activity, cell death mechanisms and topoisomerase inhibition assay.
    de Oliveira JF; Lima TS; Vendramini-Costa DB; de Lacerda Pedrosa SCB; Lafayette EA; da Silva RMF; de Almeida SMV; de Moura RO; Ruiz ALTG; de Carvalho JE; de Lima MDCA
    Eur J Med Chem; 2017 Aug; 136():305-314. PubMed ID: 28505535
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Unprecedented citrinin trimer tricitinol B functions as a novel topoisomerase IIα inhibitor.
    Du L; Liu HC; Fu W; Li DH; Pan QM; Zhu TJ; Geng MY; Gu QQ
    J Med Chem; 2011 Aug; 54(16):5796-810. PubMed ID: 21761866
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, crystal structure and antiproliferative activity of Cu(II) nalidixic acid-DACH conjugate: comparative in vitro DNA/RNA binding profile, cleavage activity and molecular docking studies.
    Arjmand F; Yousuf I; Hadda Tb; Toupet L
    Eur J Med Chem; 2014 Jun; 81():76-88. PubMed ID: 24826817
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of 2-phenylnaphthalenoid amide derivatives and their topoisomerase IIα inhibitory and antiproliferative activities.
    Wu X; Xu G; Lu C; Shen Y
    Arch Pharm (Weinheim); 2024 Oct; 357(10):e2400175. PubMed ID: 38922999
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and biological evaluation of novel perimidine o-quinone derivatives as non-intercalative topoisomerase II catalytic inhibitors.
    Zhou DC; Lu YT; Mai YW; Zhang C; Xia J; Yao PF; Wang HG; Huang SL; Huang ZS
    Bioorg Chem; 2019 Oct; 91():103131. PubMed ID: 31377387
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.