BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

261 related articles for article (PubMed ID: 28459539)

  • 1. Berberine Induces Toxicity in HeLa Cells through Perturbation of Microtubule Polymerization by Binding to Tubulin at a Unique Site.
    Raghav D; Ashraf SM; Mohan L; Rathinasamy K
    Biochemistry; 2017 May; 56(20):2594-2611. PubMed ID: 28459539
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Indirubin, a bis-indole alkaloid binds to tubulin and exhibits antimitotic activity against HeLa cells in synergism with vinblastine.
    Mohan L; Raghav D; Ashraf SM; Sebastian J; Rathinasamy K
    Biomed Pharmacother; 2018 Sep; 105():506-517. PubMed ID: 29883946
    [TBL] [Abstract][Full Text] [Related]  

  • 3. NMK-BH2, a novel microtubule-depolymerising bis (indolyl)-hydrazide-hydrazone, induces apoptotic and autophagic cell death in cervical cancer cells by binding to tubulin at colchicine - site.
    Das Mukherjee D; Kumar NM; Tantak MP; Datta S; Ghosh Dastidar D; Kumar D; Chakrabarti G
    Biochim Biophys Acta Mol Cell Res; 2020 Oct; 1867(10):118762. PubMed ID: 32502617
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NMK-TD-100, a novel microtubule modulating agent, blocks mitosis and induces apoptosis in HeLa cells by binding to tubulin.
    Bhattacharya S; Kumar NM; Ganguli A; Tantak MP; Kumar D; Chakrabarti G
    PLoS One; 2013; 8(10):e76286. PubMed ID: 24116100
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antimitotic antifungal compound benomyl inhibits brain microtubule polymerization and dynamics and cancer cell proliferation at mitosis, by binding to a novel site in tubulin.
    Gupta K; Bishop J; Peck A; Brown J; Wilson L; Panda D
    Biochemistry; 2004 Jun; 43(21):6645-55. PubMed ID: 15157098
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sertaconazole induced toxicity in HeLa cells through mitotic arrest and inhibition of microtubule assembly.
    Sebastian J; Rathinasamy K
    Naunyn Schmiedebergs Arch Pharmacol; 2021 Jun; 394(6):1231-1249. PubMed ID: 33620548
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Indicine N-oxide binds to tubulin at a distinct site and inhibits the assembly of microtubules: a mechanism for its cytotoxic activity.
    Appadurai P; Rathinasamy K
    Toxicol Lett; 2014 Feb; 225(1):66-77. PubMed ID: 24300171
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Epigallocatechin-3-gallate shows anti-proliferative activity in HeLa cells targeting tubulin-microtubule equilibrium.
    Chakrabarty S; Ganguli A; Das A; Nag D; Chakrabarti G
    Chem Biol Interact; 2015 Dec; 242():380-9. PubMed ID: 26554336
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rotenone inhibits mammalian cell proliferation by inhibiting microtubule assembly through tubulin binding.
    Srivastava P; Panda D
    FEBS J; 2007 Sep; 274(18):4788-801. PubMed ID: 17697112
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Securinine induces mitotic block in cancer cells by binding to tubulin and inhibiting microtubule assembly: A possible mechanistic basis for its anticancer activity.
    Ashraf SM; Mahanty S; Rathinasamy K
    Life Sci; 2021 Dec; 287():120105. PubMed ID: 34756929
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Thymoquinone inhibits microtubule polymerization by tubulin binding and causes mitotic arrest following apoptosis in A549 cells.
    Acharya BR; Chatterjee A; Ganguli A; Bhattacharya S; Chakrabarti G
    Biochimie; 2014 Feb; 97():78-91. PubMed ID: 24113316
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The benzophenanthridine alkaloid sanguinarine perturbs microtubule assembly dynamics through tubulin binding. A possible mechanism for its antiproliferative activity.
    Lopus M; Panda D
    FEBS J; 2006 May; 273(10):2139-50. PubMed ID: 16649991
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selective Inhibition of Spindle Microtubules by a Tubulin-Binding Quinazoline Derivative.
    Sawada JI; Ishii H; Matsuno K; Sato M; Suzuki Y; Asai A
    Mol Pharmacol; 2019 Nov; 96(5):609-618. PubMed ID: 31471455
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genistein arrests cell cycle progression of A549 cells at the G(2)/M phase and depolymerizes interphase microtubules through binding to a unique site of tubulin.
    Mukherjee S; Acharya BR; Bhattacharyya B; Chakrabarti G
    Biochemistry; 2010 Mar; 49(8):1702-12. PubMed ID: 20085293
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Perturbation of microtubule polymerization by quercetin through tubulin binding: a novel mechanism of its antiproliferative activity.
    Gupta K; Panda D
    Biochemistry; 2002 Oct; 41(43):13029-38. PubMed ID: 12390030
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules.
    Kamath K; Okouneva T; Larson G; Panda D; Wilson L; Jordan MA
    Mol Cancer Ther; 2006 Sep; 5(9):2225-33. PubMed ID: 16985056
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Vitamin K3 disrupts the microtubule networks by binding to tubulin: a novel mechanism of its antiproliferative activity.
    Acharya BR; Choudhury D; Das A; Chakrabarti G
    Biochemistry; 2009 Jul; 48(29):6963-74. PubMed ID: 19527023
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanism of mitotic arrest induced by dolastatin 15 involves loss of tension across kinetochore pairs.
    Lopus M
    Mol Cell Biochem; 2013 Oct; 382(1-2):93-102. PubMed ID: 23744533
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crocin, a carotenoid, suppresses spindle microtubule dynamics and activates the mitotic checkpoint by binding to tubulin.
    Sawant AV; Srivastava S; Prassanawar SS; Bhattacharyya B; Panda D
    Biochem Pharmacol; 2019 May; 163():32-45. PubMed ID: 30710515
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and evaluation of alpha-hydroxymethylated conjugated nitroalkenes for their anticancer activity: inhibition of cell proliferation by targeting microtubules.
    Mohan R; Rastogi N; Namboothiri IN; Mobin SM; Panda D
    Bioorg Med Chem; 2006 Dec; 14(23):8073-85. PubMed ID: 16891118
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.