BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

320 related articles for article (PubMed ID: 28467787)

  • 1. The histone deacetylase inhibitor, romidepsin, as a potential treatment for pulmonary fibrosis.
    Conforti F; Davies ER; Calderwood CJ; Thatcher TH; Jones MG; Smart DE; Mahajan S; Alzetani A; Havelock T; Maher TM; Molyneaux PL; Thorley AJ; Tetley TD; Warner JA; Packham G; Ganesan A; Skipp PJ; Marshall BJ; Richeldi L; Sime PJ; O'Reilly KMA; Davies DE
    Oncotarget; 2017 Jul; 8(30):48737-48754. PubMed ID: 28467787
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis.
    Korfei M; Stelmaszek D; MacKenzie B; Skwarna S; Chillappagari S; Bach AC; Ruppert C; Saito S; Mahavadi P; Klepetko W; Fink L; Seeger W; Lasky JA; Pullamsetti SS; Krämer OH; Guenther A
    PLoS One; 2018; 13(11):e0207915. PubMed ID: 30481203
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of class I histone deacetylases by romidepsin potently induces Epstein-Barr virus lytic cycle and mediates enhanced cell death with ganciclovir.
    Hui KF; Cheung AK; Choi CK; Yeung PL; Middeldorp JM; Lung ML; Tsao SW; Chiang AK
    Int J Cancer; 2016 Jan; 138(1):125-36. PubMed ID: 26205347
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting Histone Deacetylases in Idiopathic Pulmonary Fibrosis: A Future Therapeutic Option.
    Korfei M; Mahavadi P; Guenther A
    Cells; 2022 May; 11(10):. PubMed ID: 35626663
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Histone deacetylase inhibition promotes fibroblast apoptosis and ameliorates pulmonary fibrosis in mice.
    Sanders YY; Hagood JS; Liu H; Zhang W; Ambalavanan N; Thannickal VJ
    Eur Respir J; 2014 May; 43(5):1448-58. PubMed ID: 24603818
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Romidepsin induces cell cycle arrest, apoptosis, histone hyperacetylation and reduces matrix metalloproteinases 2 and 9 expression in bortezomib sensitized non-small cell lung cancer cells.
    Karthik S; Sankar R; Varunkumar K; Ravikumar V
    Biomed Pharmacother; 2014 Apr; 68(3):327-34. PubMed ID: 24485799
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Aberrant expression and activity of histone deacetylases in sporadic idiopathic pulmonary fibrosis.
    Korfei M; Skwarna S; Henneke I; MacKenzie B; Klymenko O; Saito S; Ruppert C; von der Beck D; Mahavadi P; Klepetko W; Bellusci S; Crestani B; Pullamsetti SS; Fink L; Seeger W; Krämer OH; Guenther A
    Thorax; 2015 Nov; 70(11):1022-32. PubMed ID: 26359372
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Romidepsin reduces histone deacetylase activity, induces acetylation of histones, inhibits proliferation, and activates apoptosis in immortalized epithelial endometriotic cells.
    Imesch P; Fink D; Fedier A
    Fertil Steril; 2010 Dec; 94(7):2838-42. PubMed ID: 20605144
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Histone deacetylase inhibition downregulates collagen 3A1 in fibrotic lung fibroblasts.
    Zhang X; Liu H; Hock T; Thannickal VJ; Sanders YY
    Int J Mol Sci; 2013 Sep; 14(10):19605-17. PubMed ID: 24084714
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A signaling cascade including ARID1A, GADD45B and DUSP1 induces apoptosis and affects the cell cycle of germ cell cancers after romidepsin treatment.
    Nettersheim D; Jostes S; Fabry M; Honecker F; Schumacher V; Kirfel J; Kristiansen G; Schorle H
    Oncotarget; 2016 Nov; 7(46):74931-74946. PubMed ID: 27572311
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Histone deacetylase inhibitor, Romidepsin (FK228) inhibits endometrial cancer cell growth through augmentation of p53-p21 pathway.
    Li LH; Zhang PR; Cai PY; Li ZC
    Biomed Pharmacother; 2016 Aug; 82():161-6. PubMed ID: 27470351
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Romidepsin: a novel histone deacetylase inhibitor for cancer.
    Bertino EM; Otterson GA
    Expert Opin Investig Drugs; 2011 Aug; 20(8):1151-8. PubMed ID: 21699444
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Suppression of BCL6 function by HDAC inhibitor mediated acetylation and chromatin modification enhances BET inhibitor effects in B-cell lymphoma cells.
    Cortiguera MG; García-Gaipo L; Wagner SD; León J; Batlle-López A; Delgado MD
    Sci Rep; 2019 Nov; 9(1):16495. PubMed ID: 31712669
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts.
    Huang SK; Scruggs AM; Donaghy J; Horowitz JC; Zaslona Z; Przybranowski S; White ES; Peters-Golden M
    Cell Death Dis; 2013 May; 4(5):e621. PubMed ID: 23640463
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Histone deacetylase inhibitor restores surfactant protein-C expression in alveolar-epithelial type II cells and attenuates bleomycin-induced pulmonary fibrosis in vivo.
    Ota C; Yamada M; Fujino N; Motohashi H; Tando Y; Takei Y; Suzuki T; Takahashi T; Kamata S; Makiguchi T; Yamaya M; Kubo H
    Exp Lung Res; 2015; 41(8):422-34. PubMed ID: 26151196
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HDAC8 inhibition ameliorates pulmonary fibrosis.
    Saito S; Zhuang Y; Suzuki T; Ota Y; Bateman ME; Alkhatib AL; Morris GF; Lasky JA
    Am J Physiol Lung Cell Mol Physiol; 2019 Jan; 316(1):L175-L186. PubMed ID: 30358439
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Romidepsin (FK228/depsipeptide) controls growth and induces apoptosis in neuroblastoma tumor cells.
    Panicker J; Li Z; McMahon C; Sizer C; Steadman K; Piekarz R; Bates SE; Thiele CJ
    Cell Cycle; 2010 May; 9(9):1830-8. PubMed ID: 20404560
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Use of class I histone deacetylase inhibitor romidepsin in combination regimens.
    Petrich A; Nabhan C
    Leuk Lymphoma; 2016 Aug; 57(8):1755-65. PubMed ID: 27118119
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Romidepsin (depsipeptide) induced cell cycle arrest, apoptosis and histone hyperacetylation in lung carcinoma cells (A549) are associated with increase in p21 and hypophosphorylated retinoblastoma proteins expression.
    Vinodhkumar R; Song YS; Devaki T
    Biomed Pharmacother; 2008 Feb; 62(2):85-93. PubMed ID: 17644301
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Defective histone acetylation is responsible for the diminished expression of cyclooxygenase 2 in idiopathic pulmonary fibrosis.
    Coward WR; Watts K; Feghali-Bostwick CA; Knox A; Pang L
    Mol Cell Biol; 2009 Aug; 29(15):4325-39. PubMed ID: 19487460
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.