BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 28472188)

  • 1. A prion-like mechanism for the propagated misfolding of SOD1 from in silico modeling of solvated near-native conformers.
    Healy EF
    PLoS One; 2017; 12(5):e0177284. PubMed ID: 28472188
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A model for gain of function in superoxide dismutase.
    Healy EF; Roth-Rodriguez A; Toledo S
    Biochem Biophys Rep; 2020 Mar; 21():100728. PubMed ID: 31970293
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An in silico study of the effect of SOD1 electrostatic loop dynamics on amyloid‑like filament formation.
    Healy EF; Cervantes L
    Eur Biophys J; 2016 Dec; 45(8):853-859. PubMed ID: 27496206
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A mechanism for propagated SOD1 misfolding from frustration analysis of a G85R mutant protein assembly.
    Healy EF
    Biochem Biophys Res Commun; 2016 Sep; 478(4):1634-9. PubMed ID: 27591900
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct conformers of transmissible misfolded SOD1 distinguish human SOD1-FALS from other forms of familial and sporadic ALS.
    Ayers JI; Diamond J; Sari A; Fromholt S; Galaleldeen A; Ostrow LW; Glass JD; Hart PJ; Borchelt DR
    Acta Neuropathol; 2016 Dec; 132(6):827-840. PubMed ID: 27704280
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TDP-43 or FUS-induced misfolded human wild-type SOD1 can propagate intercellularly in a prion-like fashion.
    Pokrishevsky E; Grad LI; Cashman NR
    Sci Rep; 2016 Mar; 6():22155. PubMed ID: 26926802
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [Prion-like Properties of Misfolded Cu/Zn-superoxide Dismutase in Amyotrophic Lateral Sclerosis: Update and Perspectives].
    Tokuda E; Marklund SL; Furukawa Y
    Yakugaku Zasshi; 2019; 139(7):1015-1019. PubMed ID: 31257248
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Intercellular Prion-Like Conversion and Transmission of Cu/Zn Superoxide Dismutase (SOD1) in Cell Culture.
    Grad LI; Pokrishevsky E; Cashman NR
    Methods Mol Biol; 2017; 1658():357-367. PubMed ID: 28861801
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosis.
    Pokrishevsky E; Grad LI; Yousefi M; Wang J; Mackenzie IR; Cashman NR
    PLoS One; 2012; 7(4):e35050. PubMed ID: 22493728
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Disease Mechanisms in ALS: Misfolded SOD1 Transferred Through Exosome-Dependent and Exosome-Independent Pathways.
    Silverman JM; Fernando SM; Grad LI; Hill AF; Turner BJ; Yerbury JJ; Cashman NR
    Cell Mol Neurobiol; 2016 Apr; 36(3):377-81. PubMed ID: 26908139
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SOD1 in neurotoxicity and its controversial roles in SOD1 mutation-negative ALS.
    Hayashi Y; Homma K; Ichijo H
    Adv Biol Regul; 2016 Jan; 60():95-104. PubMed ID: 26563614
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Metal-Free, Disulfide Oxidized Form of Superoxide Dismutase 1 as a Primary Misfolded Species with Prion-Like Properties in the Extracellular Environments Surrounding Motor Neuron-Like Cells.
    Takashima C; Kosuge Y; Inoue M; Ono SI; Tokuda E
    Int J Mol Sci; 2021 Apr; 22(8):. PubMed ID: 33923808
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Wild-type Cu/Zn-superoxide dismutase is misfolded in cerebrospinal fluid of sporadic amyotrophic lateral sclerosis.
    Tokuda E; Takei YI; Ohara S; Fujiwara N; Hozumi I; Furukawa Y
    Mol Neurodegener; 2019 Nov; 14(1):42. PubMed ID: 31744522
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of maturation on the conformational free-energy landscape of SOD1.
    Culik RM; Sekhar A; Nagesh J; Deol H; Rumfeldt JAO; Meiering EM; Kay LE
    Proc Natl Acad Sci U S A; 2018 Mar; 115(11):E2546-E2555. PubMed ID: 29483249
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Superoxide Dismutase 1 (SOD1)-Derived Peptide Inhibits Amyloid Aggregation of Familial Amyotrophic Lateral Sclerosis SOD1 Mutants.
    Banerjee V; Shani T; Katzman B; Vyazmensky M; Papo N; Israelson A; Engel S
    ACS Chem Neurosci; 2016 Nov; 7(11):1595-1606. PubMed ID: 27540759
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The prion-like nature of amyotrophic lateral sclerosis.
    McAlary L; Yerbury JJ; Cashman NR
    Prog Mol Biol Transl Sci; 2020; 175():261-296. PubMed ID: 32958236
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prion-like activity of Cu/Zn superoxide dismutase: implications for amyotrophic lateral sclerosis.
    Grad LI; Cashman NR
    Prion; 2014; 8(1):33-41. PubMed ID: 24394345
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A misfolded dimer of Cu/Zn-superoxide dismutase leading to pathological oligomerization in amyotrophic lateral sclerosis.
    Anzai I; Tokuda E; Mukaiyama A; Akiyama S; Endo F; Yamanaka K; Misawa H; Furukawa Y
    Protein Sci; 2017 Mar; 26(3):484-496. PubMed ID: 27977888
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tryptophan residue 32 in human Cu-Zn superoxide dismutase modulates prion-like propagation and strain selection.
    Crown A; McAlary L; Fagerli E; Brown H; Yerbury JJ; Galaleldeen A; Cashman NR; Borchelt DR; Ayers JI
    PLoS One; 2020; 15(1):e0227655. PubMed ID: 31999698
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Prion Properties of SOD1 in Amyotrophic Lateral Sclerosis and Potential Therapy.
    Sibilla C; Bertolotti A
    Cold Spring Harb Perspect Biol; 2017 Oct; 9(10):. PubMed ID: 28096265
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.