583 related articles for article (PubMed ID: 28475832)
1. A Phenotypic Based Target Screening Approach Delivers New Antitubercular CTP Synthetase Inhibitors.
Esposito M; Szadocka S; Degiacomi G; Orena BS; Mori G; Piano V; Boldrin F; Zemanová J; Huszár S; Barros D; Ekins S; Lelièvre J; Manganelli R; Mattevi A; Pasca MR; Riccardi G; Ballell L; Mikušová K; Chiarelli LR
ACS Infect Dis; 2017 Jun; 3(6):428-437. PubMed ID: 28475832
[TBL] [Abstract][Full Text] [Related]
2. Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG.
Mori G; Chiarelli LR; Esposito M; Makarov V; Bellinzoni M; Hartkoorn RC; Degiacomi G; Boldrin F; Ekins S; de Jesus Lopes Ribeiro AL; Marino LB; Centárová I; Svetlíková Z; Blaško J; Kazakova E; Lepioshkin A; Barilone N; Zanoni G; Porta A; Fondi M; Fani R; Baulard AR; Mikušová K; Alzari PM; Manganelli R; de Carvalho LP; Riccardi G; Cole ST; Pasca MR
Chem Biol; 2015 Jul; 22(7):917-27. PubMed ID: 26097035
[TBL] [Abstract][Full Text] [Related]
3. High-throughput screen identifies small molecule inhibitors targeting acetyltransferase activity of Mycobacterium tuberculosis GlmU.
Rani C; Mehra R; Sharma R; Chib R; Wazir P; Nargotra A; Khan IA
Tuberculosis (Edinb); 2015 Dec; 95(6):664-677. PubMed ID: 26318557
[TBL] [Abstract][Full Text] [Related]
4. Discovery of Mycobacterium tuberculosis α-1,4-glucan branching enzyme (GlgB) inhibitors by structure- and ligand-based virtual screening.
Dkhar HK; Gopalsamy A; Loharch S; Kaur A; Bhutani I; Saminathan K; Bhagyaraj E; Chandra V; Swaminathan K; Agrawal P; Parkesh R; Gupta P
J Biol Chem; 2015 Jan; 290(1):76-89. PubMed ID: 25384979
[TBL] [Abstract][Full Text] [Related]
5. Identification of a novel inhibitor of isocitrate lyase as a potent antitubercular agent against both active and non-replicating Mycobacterium tuberculosis.
Liu Y; Zhou S; Deng Q; Li X; Meng J; Guan Y; Li C; Xiao C
Tuberculosis (Edinb); 2016 Mar; 97():38-46. PubMed ID: 26980494
[TBL] [Abstract][Full Text] [Related]
6. Screening of antitubercular compound library identifies novel ATP synthase inhibitors of Mycobacterium tuberculosis.
Kumar S; Mehra R; Sharma S; Bokolia NP; Raina D; Nargotra A; Singh PP; Khan IA
Tuberculosis (Edinb); 2018 Jan; 108():56-63. PubMed ID: 29523328
[TBL] [Abstract][Full Text] [Related]
7. High throughput screen identifies small molecule inhibitors specific for Mycobacterium tuberculosis phosphoserine phosphatase.
Arora G; Tiwari P; Mandal RS; Gupta A; Sharma D; Saha S; Singh R
J Biol Chem; 2014 Sep; 289(36):25149-65. PubMed ID: 25037224
[TBL] [Abstract][Full Text] [Related]
8. A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK.
Chiarelli LR; Mori G; Orena BS; Esposito M; Lane T; de Jesus Lopes Ribeiro AL; Degiacomi G; Zemanová J; Szádocka S; Huszár S; Palčeková Z; Manfredi M; Gosetti F; Lelièvre J; Ballell L; Kazakova E; Makarov V; Marengo E; Mikusova K; Cole ST; Riccardi G; Ekins S; Pasca MR
Sci Rep; 2018 Feb; 8(1):3187. PubMed ID: 29453370
[TBL] [Abstract][Full Text] [Related]
9. Identification of New MmpL3 Inhibitors by Untargeted and Targeted Mutant Screens Defines MmpL3 Domains with Differential Resistance.
Williams JT; Haiderer ER; Coulson GB; Conner KN; Ellsworth E; Chen C; Alvarez-Cabrera N; Li W; Jackson M; Dick T; Abramovitch RB
Antimicrob Agents Chemother; 2019 Oct; 63(10):. PubMed ID: 31405862
[TBL] [Abstract][Full Text] [Related]
10. NU-6027 Inhibits Growth of Mycobacterium tuberculosis by Targeting Protein Kinase D and Protein Kinase G.
Kidwai S; Bouzeyen R; Chakraborti S; Khare N; Das S; Priya Gosain T; Behura A; Meena CL; Dhiman R; Essafi M; Bajaj A; Saini DK; Srinivasan N; Mahajan D; Singh R
Antimicrob Agents Chemother; 2019 Sep; 63(9):. PubMed ID: 31285226
[TBL] [Abstract][Full Text] [Related]
11. Identification and development of 2-methylimidazo[1,2-a]pyridine-3-carboxamides as Mycobacterium tuberculosis pantothenate synthetase inhibitors.
Samala G; Nallangi R; Devi PB; Saxena S; Yadav R; Sridevi JP; Yogeeswari P; Sriram D
Bioorg Med Chem; 2014 Aug; 22(15):4223-32. PubMed ID: 24953948
[TBL] [Abstract][Full Text] [Related]
12. 2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1.
Neres J; Hartkoorn RC; Chiarelli LR; Gadupudi R; Pasca MR; Mori G; Venturelli A; Savina S; Makarov V; Kolly GS; Molteni E; Binda C; Dhar N; Ferrari S; Brodin P; Delorme V; Landry V; de Jesus Lopes Ribeiro AL; Farina D; Saxena P; Pojer F; Carta A; Luciani R; Porta A; Zanoni G; De Rossi E; Costi MP; Riccardi G; Cole ST
ACS Chem Biol; 2015 Mar; 10(3):705-14. PubMed ID: 25427196
[TBL] [Abstract][Full Text] [Related]
13. Biophysical Screening of a Focused Library for the Discovery of CYP121 Inhibitors as Novel Antimycobacterials.
Brengel C; Thomann A; Schifrin A; Allegretta G; Kamal AAM; Haupenthal J; Schnorr I; Cho SH; Franzblau SG; Empting M; Eberhard J; Hartmann RW
ChemMedChem; 2017 Oct; 12(19):1616-1626. PubMed ID: 28815923
[TBL] [Abstract][Full Text] [Related]
14. Structure-based virtual screening as a tool for the identification of novel inhibitors against Mycobacterium tuberculosis 3-dehydroquinate dehydratase.
Petersen GO; Saxena S; Renuka J; Soni V; Yogeeswari P; Santos DS; Bizarro CV; Sriram D
J Mol Graph Model; 2015 Jul; 60():124-31. PubMed ID: 26043661
[TBL] [Abstract][Full Text] [Related]
15. Discovery of novel lysine ɛ-aminotransferase inhibitors: An intriguing potential target for latent tuberculosis.
Devi PB; Sridevi JP; Kakan SS; Saxena S; Jeankumar VU; Soni V; Anantaraju HS; Yogeeswari P; Sriram D
Tuberculosis (Edinb); 2015 Dec; 95(6):786-794. PubMed ID: 26299907
[TBL] [Abstract][Full Text] [Related]
16. Why are membrane targets discovered by phenotypic screens and genome sequencing in Mycobacterium tuberculosis?
Goldman RC
Tuberculosis (Edinb); 2013 Nov; 93(6):569-88. PubMed ID: 24119636
[TBL] [Abstract][Full Text] [Related]
17. Design, chemical synthesis of 3-(9H-fluoren-9-yl)pyrrolidine-2,5-dione derivatives and biological activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis.
Matviiuk T; Rodriguez F; Saffon N; Mallet-Ladeira S; Gorichko M; de Jesus Lopes Ribeiro AL; Pasca MR; Lherbet C; Voitenko Z; Baltas M
Eur J Med Chem; 2013; 70():37-48. PubMed ID: 24140915
[TBL] [Abstract][Full Text] [Related]
18. Direct inhibitors of InhA are active against Mycobacterium tuberculosis.
Manjunatha UH; S Rao SP; Kondreddi RR; Noble CG; Camacho LR; Tan BH; Ng SH; Ng PS; Ma NL; Lakshminarayana SB; Herve M; Barnes SW; Yu W; Kuhen K; Blasco F; Beer D; Walker JR; Tonge PJ; Glynne R; Smith PW; Diagana TT
Sci Transl Med; 2015 Jan; 7(269):269ra3. PubMed ID: 25568071
[TBL] [Abstract][Full Text] [Related]
19. Discovery of novel InhA reductase inhibitors: application of pharmacophore- and shape-based screening approach.
Kumar UC; Bvs SK; Mahmood S; D S; Kumar-Sahu P; Pulakanam S; Ballell L; Alvarez-Gomez D; Malik S; Jarp S
Future Med Chem; 2013 Mar; 5(3):249-59. PubMed ID: 23464516
[TBL] [Abstract][Full Text] [Related]
20. Discovery of new
Mehra R; Chib R; Munagala G; Yempalla KR; Khan IA; Singh PP; Khan FG; Nargotra A
Mol Divers; 2015 Nov; 19(4):1003-19. PubMed ID: 26232029
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]