BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

628 related articles for article (PubMed ID: 28483418)

  • 1. Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.
    Dorighi KM; Swigut T; Henriques T; Bhanu NV; Scruggs BS; Nady N; Still CD; Garcia BA; Adelman K; Wysocka J
    Mol Cell; 2017 May; 66(4):568-576.e4. PubMed ID: 28483418
    [TBL] [Abstract][Full Text] [Related]  

  • 2. H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.
    Lee JE; Wang C; Xu S; Cho YW; Wang L; Feng X; Baldridge A; Sartorelli V; Zhuang L; Peng W; Ge K
    Elife; 2013 Dec; 2():e01503. PubMed ID: 24368734
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription.
    Wang SP; Tang Z; Chen CW; Shimada M; Koche RP; Wang LH; Nakadai T; Chramiec A; Krivtsov AV; Armstrong SA; Roeder RG
    Mol Cell; 2017 Jul; 67(2):308-321.e6. PubMed ID: 28732206
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition.
    Wang C; Lee JE; Lai B; Macfarlan TS; Xu S; Zhuang L; Liu C; Peng W; Ge K
    Proc Natl Acad Sci U S A; 2016 Oct; 113(42):11871-11876. PubMed ID: 27698142
    [TBL] [Abstract][Full Text] [Related]  

  • 5. H3K4me1 facilitates promoter-enhancer interactions and gene activation during embryonic stem cell differentiation.
    Kubo N; Chen PB; Hu R; Ye Z; Sasaki H; Ren B
    Mol Cell; 2024 May; 84(9):1742-1752.e5. PubMed ID: 38513661
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4.
    Herz HM; Mohan M; Garruss AS; Liang K; Takahashi YH; Mickey K; Voets O; Verrijzer CP; Shilatifard A
    Genes Dev; 2012 Dec; 26(23):2604-20. PubMed ID: 23166019
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.
    Hu D; Gao X; Morgan MA; Herz HM; Smith ER; Shilatifard A
    Mol Cell Biol; 2013 Dec; 33(23):4745-54. PubMed ID: 24081332
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutant p53 regulates enhancer-associated H3K4 monomethylation through interactions with the methyltransferase MLL4.
    Rahnamoun H; Hong J; Sun Z; Lee J; Lu H; Lauberth SM
    J Biol Chem; 2018 Aug; 293(34):13234-13246. PubMed ID: 29954944
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers.
    Yan J; Chen SA; Local A; Liu T; Qiu Y; Dorighi KM; Preissl S; Rivera CM; Wang C; Ye Z; Ge K; Hu M; Wysocka J; Ren B
    Cell Res; 2018 Feb; 28(2):204-220. PubMed ID: 29313530
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.
    Rickels R; Herz HM; Sze CC; Cao K; Morgan MA; Collings CK; Gause M; Takahashi YH; Wang L; Rendleman EJ; Marshall SA; Krueger A; Bartom ET; Piunti A; Smith ER; Abshiru NA; Kelleher NL; Dorsett D; Shilatifard A
    Nat Genet; 2017 Nov; 49(11):1647-1653. PubMed ID: 28967912
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation.
    Boileau RM; Chen KX; Blelloch R
    Genome Biol; 2023 Mar; 24(1):41. PubMed ID: 36869380
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape.
    Wang LH; Aberin MAE; Wu S; Wang SP
    Biochem Soc Trans; 2021 Jun; 49(3):1041-1054. PubMed ID: 34156443
    [TBL] [Abstract][Full Text] [Related]  

  • 13. H3K4 Methyltransferase Activity Is Required for MLL4 Protein Stability.
    Jang Y; Wang C; Zhuang L; Liu C; Ge K
    J Mol Biol; 2017 Jun; 429(13):2046-2054. PubMed ID: 28013028
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Histone H3K4me1 and H3K27ac play roles in nucleosome eviction and eRNA transcription, respectively, at enhancers.
    Kang Y; Kim YW; Kang J; Kim A
    FASEB J; 2021 Aug; 35(8):e21781. PubMed ID: 34309923
    [TBL] [Abstract][Full Text] [Related]  

  • 15. H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development.
    Jang Y; Broun A; Wang C; Park YK; Zhuang L; Lee JE; Froimchuk E; Liu C; Ge K
    Nucleic Acids Res; 2019 Jan; 47(2):607-620. PubMed ID: 30335158
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Histone H3K4me1 strongly activates the DNase I hypersensitive sites in super-enhancers than those in typical enhancers.
    Kang Y; Kang J; Kim A
    Biosci Rep; 2021 Jul; 41(7):. PubMed ID: 34195788
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.
    Lai B; Lee JE; Jang Y; Wang L; Peng W; Ge K
    Nucleic Acids Res; 2017 Jun; 45(11):6388-6403. PubMed ID: 28398509
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A role for H3K4 monomethylation in gene repression and partitioning of chromatin readers.
    Cheng J; Blum R; Bowman C; Hu D; Shilatifard A; Shen S; Dynlacht BD
    Mol Cell; 2014 Mar; 53(6):979-92. PubMed ID: 24656132
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Histone H3K4ac, as a marker of active transcription start sites and enhancers, plays roles in histone eviction and RNA transcription.
    Kang J; Kang Y; Kim A
    Biochim Biophys Acta Gene Regul Mech; 2024 Jun; 1867(2):195021. PubMed ID: 38417480
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Distinct kinetic mechanisms of H3K4 methylation catalyzed by MLL3 and MLL4 core complexes.
    Zheng Y; Huang Y; Mencius J; Li Y; Zhao L; Luo W; Chen Y; Quan S
    J Biol Chem; 2021; 296():100635. PubMed ID: 33823156
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.