BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

307 related articles for article (PubMed ID: 28487144)

  • 1. Intestinal absorption mechanisms of 2'-deoxy-2'-β-fluoro-4'-azidocytidine, a cytidine analog for AIDS treatment, and its interaction with P-glycoprotein, multidrug resistance-associated protein 2 and breast cancer resistance protein.
    Liu Y; Liu B; Zhang Y; Peng Y; Huang C; Wang N; Jiang J; Wang Q; Chang J
    Eur J Pharm Sci; 2017 Jul; 105():150-158. PubMed ID: 28487144
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of the antiretroviral drug 2'-deoxy-2'-β-fluoro-4'-azidocytidine (FNC) on P-gp, MRP2 and BCRP expressions and functions.
    Liu Y; Wang Y; Peng Y; Liu B; Ma F; Jiang J; Wang Q; Chang J
    Pharmazie; 2018 Sep; 73(9):503-507. PubMed ID: 30223932
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Multiple efflux pumps are involved in the transepithelial transport of colchicine: combined effect of p-glycoprotein and multidrug resistance-associated protein 2 leads to decreased intestinal absorption throughout the entire small intestine.
    Dahan A; Sabit H; Amidon GL
    Drug Metab Dispos; 2009 Oct; 37(10):2028-36. PubMed ID: 19589874
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Small intestinal efflux mediated by MRP2 and BCRP shifts sulfasalazine intestinal permeability from high to low, enabling its colonic targeting.
    Dahan A; Amidon GL
    Am J Physiol Gastrointest Liver Physiol; 2009 Aug; 297(2):G371-7. PubMed ID: 19541926
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prandial state and biological sex modulate clinically relevant efflux transporters to different extents in Wistar and Sprague Dawley rats.
    Gavins FKH; Dou L; Qin Y; Madla CM; Murdan S; Basit AW; Mai Y; Orlu M
    Biomed Pharmacother; 2023 Apr; 160():114329. PubMed ID: 36731343
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The H2 receptor antagonist nizatidine is a P-glycoprotein substrate: characterization of its intestinal epithelial cell efflux transport.
    Dahan A; Sabit H; Amidon GL
    AAPS J; 2009 Jun; 11(2):205-13. PubMed ID: 19319690
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Studies on pharmacokinetic properties and absorption mechanism of phloretin: In vivo and in vitro.
    Zhao YY; Fan Y; Wang M; Wang J; Cheng JX; Zou JB; Zhang XF; Shi YJ; Guo DY
    Biomed Pharmacother; 2020 Dec; 132():110809. PubMed ID: 33049584
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge.
    Yu XY; Lin SG; Zhou ZW; Chen X; Liang J; Liu PQ; Duan W; Chowbay B; Wen JY; Li CG; Zhou SF
    Curr Drug Metab; 2007 May; 8(4):325-40. PubMed ID: 17504222
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Multidrug resistance-associated protein 2 (MRP2) is an efflux transporter of EGCG and its metabolites in the human small intestine.
    Kikuchi T; Hayashi A; Ikeda N; Morita O; Tasaki J
    J Nutr Biochem; 2022 Sep; 107():109071. PubMed ID: 35636688
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vitro and in situ study on characterization and mechanism of the intestinal absorption of 2,3,5,4'-tetrahydroxy-stilbene-2-O-β-D-glucoside.
    Wang C; Zhou Y; Gong X; Zheng L; Li Y
    BMC Pharmacol Toxicol; 2020 Jan; 21(1):7. PubMed ID: 31969193
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide.
    Li Y; Song W; Ou X; Luo G; Xie Y; Sun R; Wang Y; Qi X; Hu M; Liu Z; Zhu L
    Drug Metab Dispos; 2019 Mar; 47(3):203-214. PubMed ID: 30602435
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Aristolochic acid I is a substrate of BCRP but not P-glycoprotein or MRP2.
    Ma L; Qin Y; Shen Z; Bi H; Hu H; Huang M; Zhou H; Yu L; Jiang H; Zeng S
    J Ethnopharmacol; 2015 Aug; 172():430-5. PubMed ID: 26183576
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparative Hepatic and Intestinal Efflux Transport of Statins.
    Deng F; Tuomi SK; Neuvonen M; Hirvensalo P; Kulju S; Wenzel C; Oswald S; Filppula AM; Niemi M
    Drug Metab Dispos; 2021 Sep; 49(9):750-759. PubMed ID: 34162690
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transport characteristics of tryptanthrin and its inhibitory effect on P-gp and MRP2 in Caco-2 cells.
    Zhu X; Zhang X; Ma G; Yan J; Wang H; Yang Q
    J Pharm Pharm Sci; 2011; 14(3):325-35. PubMed ID: 21824448
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential selectivity of efflux transporter inhibitors in Caco-2 and MDCK-MDR1 monolayers: a strategy to assess the interaction of a new chemical entity with P-gp, BCRP, and MRP2.
    Mease K; Sane R; Podila L; Taub ME
    J Pharm Sci; 2012 May; 101(5):1888-97. PubMed ID: 22359351
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Downregulated expression of intestinal P-glycoprotein in rats with cisplatin-induced acute kidney injury causes amplification of its transport capacity to maintain "gatekeeper" function.
    Takeda F; Oda M; Terasaki M; Ichimura Y; Kojima H; Saitoh H
    Toxicol Appl Pharmacol; 2021 Jul; 423():115570. PubMed ID: 33965372
    [TBL] [Abstract][Full Text] [Related]  

  • 17. P-glycoprotein and breast cancer resistance protein affect disposition of tandutinib, a tyrosine kinase inhibitor.
    Yang JJ; Milton MN; Yu S; Liao M; Liu N; Wu JT; Gan L; Balani SK; Lee FW; Prakash S; Xia CQ
    Drug Metab Lett; 2010 Dec; 4(4):201-12. PubMed ID: 20670210
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Intestinal absorption mechanisms of prenylated flavonoids present in the heat-processed Epimedium koreanum Nakai (Yin Yanghuo).
    Chen Y; Zhao YH; Jia XB; Hu M
    Pharm Res; 2008 Sep; 25(9):2190-9. PubMed ID: 18459036
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The role of efflux transporters on the transport of highly toxic aconitine, mesaconitine, hypaconitine, and their hydrolysates, as determined in cultured Caco-2 and transfected MDCKII cells.
    Ye L; Yang X; Yang Z; Gao S; Yin T; Liu W; Wang F; Hu M; Liu Z
    Toxicol Lett; 2013 Feb; 216(2-3):86-99. PubMed ID: 23200901
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Involvement of P-glycoprotein, multidrug resistance protein 2 and breast cancer resistance protein in the transport of belotecan and topotecan in Caco-2 and MDCKII cells.
    Li H; Jin HE; Kim W; Han YH; Kim DD; Chung SJ; Shim CK
    Pharm Res; 2008 Nov; 25(11):2601-12. PubMed ID: 18654741
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.