133 related articles for article (PubMed ID: 28488849)
1. Solution Conformations and Dynamics of Substrate-Bound Cytochrome P450 MycG.
Tietz DR; Podust LM; Sherman DH; Pochapsky TC
Biochemistry; 2017 May; 56(21):2701-2714. PubMed ID: 28488849
[TBL] [Abstract][Full Text] [Related]
2. Substrate recognition by the multifunctional cytochrome P450 MycG in mycinamicin hydroxylation and epoxidation reactions.
Li S; Tietz DR; Rutaganira FU; Kells PM; Anzai Y; Kato F; Pochapsky TC; Sherman DH; Podust LM
J Biol Chem; 2012 Nov; 287(45):37880-90. PubMed ID: 22952225
[TBL] [Abstract][Full Text] [Related]
3. Function of cytochrome P450 enzymes MycCI and MycG in Micromonospora griseorubida, a producer of the macrolide antibiotic mycinamicin.
Anzai Y; Tsukada S; Sakai A; Masuda R; Harada C; Domeki A; Li S; Kinoshita K; Sherman DH; Kato F
Antimicrob Agents Chemother; 2012 Jul; 56(7):3648-56. PubMed ID: 22547618
[TBL] [Abstract][Full Text] [Related]
4. Engineering sequence and selectivity of late-stage C-H oxidation in the MycG iterative cytochrome P450.
Iizaka Y; Arai R; Takahashi A; Ito M; Sakai M; Fukumoto A; Sherman DH; Anzai Y
J Ind Microbiol Biotechnol; 2022 Jan; 49(1):. PubMed ID: 34543433
[TBL] [Abstract][Full Text] [Related]
5. Some Surprising Implications of NMR-directed Simulations of Substrate Recognition and Binding by Cytochrome P450
Asciutto EK; Pochapsky TC
J Mol Biol; 2018 Apr; 430(9):1295-1310. PubMed ID: 29596916
[TBL] [Abstract][Full Text] [Related]
6. Functional analysis of MycCI and MycG, cytochrome P450 enzymes involved in biosynthesis of mycinamicin macrolide antibiotics.
Anzai Y; Li S; Chaulagain MR; Kinoshita K; Kato F; Montgomery J; Sherman DH
Chem Biol; 2008 Sep; 15(9):950-9. PubMed ID: 18804032
[TBL] [Abstract][Full Text] [Related]
7. Computational-Based Mechanistic Study and Engineering of Cytochrome P450 MycG for Selective Oxidation of 16-Membered Macrolide Antibiotics.
Yang S; DeMars MD; Grandner JM; Olson NM; Anzai Y; Sherman DH; Houk KN
J Am Chem Soc; 2020 Oct; 142(42):17981-17988. PubMed ID: 33030347
[TBL] [Abstract][Full Text] [Related]
8. What Your Crystal Structure Will Not Tell You about Enzyme Function.
Pochapsky TC; Pochapsky SS
Acc Chem Res; 2019 May; 52(5):1409-1418. PubMed ID: 31034199
[TBL] [Abstract][Full Text] [Related]
9. Substrate recognition by two different P450s: Evidence for conserved roles in a common fold.
Tietz DR; Colthart AM; Sondej Pochapsky S; Pochapsky TC
Sci Rep; 2017 Oct; 7(1):13581. PubMed ID: 29051575
[TBL] [Abstract][Full Text] [Related]
10. Solution structural ensembles of substrate-free cytochrome P450(cam).
Asciutto EK; Young MJ; Madura J; Pochapsky SS; Pochapsky TC
Biochemistry; 2012 Apr; 51(16):3383-93. PubMed ID: 22468842
[TBL] [Abstract][Full Text] [Related]
11. Exploring the molecular basis for substrate specificity in homologous macrolide biosynthetic cytochromes P450.
DeMars MD; Samora NL; Yang S; Garcia-Borràs M; Sanders JN; Houk KN; Podust LM; Sherman DH
J Biol Chem; 2019 Nov; 294(44):15947-15961. PubMed ID: 31488542
[TBL] [Abstract][Full Text] [Related]
12. Conformational heterogeneity suggests multiple substrate binding modes in CYP106A2.
Wong NR; Sundar R; Kazanis S; Biswas J; Pochapsky TC
J Inorg Biochem; 2023 Apr; 241():112129. PubMed ID: 36731370
[TBL] [Abstract][Full Text] [Related]
13. New reactions and products resulting from alternative interactions between the P450 enzyme and redox partners.
Zhang W; Liu Y; Yan J; Cao S; Bai F; Yang Y; Huang S; Yao L; Anzai Y; Kato F; Podust LM; Sherman DH; Li S
J Am Chem Soc; 2014 Mar; 136(9):3640-6. PubMed ID: 24521145
[TBL] [Abstract][Full Text] [Related]
14. Molecular dynamics simulations of P450 BM3--examination of substrate-induced conformational change.
Chang YT; Loew GH
J Biomol Struct Dyn; 1999 Jun; 16(6):1189-203. PubMed ID: 10447203
[TBL] [Abstract][Full Text] [Related]
15. Structure, dynamics, and function of the monooxygenase P450 BM-3: insights from computer simulations studies.
Roccatano D
J Phys Condens Matter; 2015 Jul; 27(27):273102. PubMed ID: 26061496
[TBL] [Abstract][Full Text] [Related]
16. Differential behavior of the sub-sites of cytochrome 450 active site in binding of substrates, and products (implications for coupling/uncoupling).
Narasimhulu S
Biochim Biophys Acta; 2007 Mar; 1770(3):360-75. PubMed ID: 17134838
[TBL] [Abstract][Full Text] [Related]
17. Experimentally restrained molecular dynamics simulations for characterizing the open states of cytochrome P450cam.
Asciutto EK; Dang M; Pochapsky SS; Madura JD; Pochapsky TC
Biochemistry; 2011 Mar; 50(10):1664-71. PubMed ID: 21265500
[TBL] [Abstract][Full Text] [Related]
18. Detection of substrate-dependent conformational changes in the P450 fold by nuclear magnetic resonance.
Colthart AM; Tietz DR; Ni Y; Friedman JL; Dang M; Pochapsky TC
Sci Rep; 2016 Feb; 6():22035. PubMed ID: 26911901
[TBL] [Abstract][Full Text] [Related]
19. Filling a hole in cytochrome P450 BM3 improves substrate binding and catalytic efficiency.
Huang WC; Westlake AC; Maréchal JD; Joyce MG; Moody PC; Roberts GC
J Mol Biol; 2007 Oct; 373(3):633-51. PubMed ID: 17868686
[TBL] [Abstract][Full Text] [Related]
20. Docking of protein-protein complexes on the basis of highly ambiguous intermolecular distance restraints derived from 1H/15N chemical shift mapping and backbone 15N-1H residual dipolar couplings using conjoined rigid body/torsion angle dynamics.
Clore GM; Schwieters CD
J Am Chem Soc; 2003 Mar; 125(10):2902-12. PubMed ID: 12617657
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]