BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 28495902)

  • 1. Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers.
    Uehara S; Ishii S; Uno Y; Inoue T; Sasaki E; Yamazaki H
    Drug Metab Dispos; 2017 Aug; 45(8):896-899. PubMed ID: 28495902
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone.
    Uehara S; Uno Y; Nakanishi K; Ishii S; Inoue T; Sasaki E; Yamazaki H
    Drug Metab Dispos; 2017 May; 45(5):457-467. PubMed ID: 28196829
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oxidation of R- and S-omeprazole stereoselectively mediated by liver microsomal cytochrome P450 2C19 enzymes from cynomolgus monkeys and common marmosets.
    Uehara S; Kawano M; Murayama N; Uno Y; Utoh M; Inoue T; Sasaki E; Yamazaki H
    Biochem Pharmacol; 2016 Nov; 120():56-62. PubMed ID: 27641812
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Marmoset cytochrome P450 2D8 in livers and small intestines metabolizes typical human P450 2D6 substrates, metoprolol, bufuralol and dextromethorphan.
    Uehara S; Uno Y; Hagihira Y; Murayama N; Shimizu M; Inoue T; Sasaki E; Yamazaki H
    Xenobiotica; 2015; 45(9):766-72. PubMed ID: 25801057
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regioselective hydroxylation of an antiarrhythmic drug, propafenone, mediated by rat liver cytochrome P450 2D2 differs from that catalyzed by human P450 2D6.
    Uehara S; Murayama N; Yamazaki H; Suemizu H
    Xenobiotica; 2019 Nov; 49(11):1323-1331. PubMed ID: 30596462
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation and deactivation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by cytochrome P450 enzymes and flavin-containing monooxygenases in common marmosets (Callithrix jacchus).
    Uehara S; Uno Y; Inoue T; Murayama N; Shimizu M; Sasaki E; Yamazaki H
    Drug Metab Dispos; 2015 May; 43(5):735-42. PubMed ID: 25735838
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Survey of Drug Oxidation Activities in Hepatic and Intestinal Microsomes of Individual Common Marmosets, a New Nonhuman Primate Animal Model.
    Uehara S; Oshio T; Nakanishi K; Tomioka E; Suzuki M; Inoue T; Uno Y; Sasaki E; Yamazaki H
    Curr Drug Metab; 2019; 20(2):103-113. PubMed ID: 30280664
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Progesterone hydroxylation by cytochromes P450 2C and 3A enzymes in marmoset liver microsomes.
    Nakanishi K; Uehara S; Uno Y; Inoue T; Sasaki E; Yamazaki H
    Xenobiotica; 2018 Aug; 48(8):757-763. PubMed ID: 28762864
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vivo and in vitro diclofenac 5-hydroxylation mediated primarily by cytochrome P450 3A enzymes in common marmoset livers genotyped for P450 2C19 variants.
    Nakanishi K; Uehara S; Kusama T; Inoue T; Shimura K; Kamiya Y; Murayama N; Shimizu M; Uno Y; Sasaki E; Yamazaki H
    Biochem Pharmacol; 2018 Jun; 152():272-278. PubMed ID: 29626440
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A New Marmoset P450 4F12 Enzyme Expressed in Small Intestines and Livers Efficiently Metabolizes Antihistaminic Drug Ebastine.
    Uehara S; Uno Y; Yuki Y; Inoue T; Sasaki E; Yamazaki H
    Drug Metab Dispos; 2016 Jun; 44(6):833-41. PubMed ID: 27044800
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Terfenadine t-butyl hydroxylation catalyzed by human and marmoset cytochrome P450 3A and 4F enzymes in livers and small intestines.
    Uehara S; Yuki Y; Uno Y; Inoue T; Sasaki E; Yamazaki H
    Xenobiotica; 2018 Apr; 48(4):342-347. PubMed ID: 28436281
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Caffeine 7-N-demethylation and C-8-oxidation mediated by liver microsomal cytochrome P450 enzymes in common marmosets.
    Uehara S; Uno Y; Inoue T; Suzuki T; Utoh M; Sasaki E; Yamazaki H
    Xenobiotica; 2016 Jul; 46(7):573-578. PubMed ID: 26503341
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Simultaneous pharmacokinetics evaluation of human cytochrome P450 probes, caffeine, warfarin, omeprazole, metoprolol and midazolam, in common marmosets (Callithrix jacchus).
    Uehara S; Inoue T; Utoh M; Toda A; Shimizu M; Uno Y; Sasaki E; Yamazaki H
    Xenobiotica; 2016; 46(2):163-8. PubMed ID: 26114209
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Use of quinidine inhibition to define the role of the sparteine/debrisoquine cytochrome P450 in metoprolol oxidation by human liver microsomes.
    Otton SV; Crewe HK; Lennard MS; Tucker GT; Woods HF
    J Pharmacol Exp Ther; 1988 Oct; 247(1):242-7. PubMed ID: 3171974
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional characterization and tissue expression of marmoset cytochrome P450 2E1.
    Uehara S; Uno Y; Tomioka E; Inoue T; Sasaki E; Yamazaki H
    Biopharm Drug Dispos; 2017 Sep; 38(6):394-397. PubMed ID: 28474789
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evidence that serine 304 is not a key ligand-binding residue in the active site of cytochrome P450 2D6.
    Ellis SW; Hayhurst GP; Lightfoot T; Smith G; Harlow J; Rowland-Yeo K; Larsson C; Mahling J; Lim CK; Wolf CR; Blackburn MG; Lennard MS; Tucker GT
    Biochem J; 2000 Feb; 345 Pt 3(Pt 3):565-71. PubMed ID: 10642515
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes.
    Yamazaki H; Guo Z; Persmark M; Mimura M; Inoue K; Guengerich FP; Shimada T
    Mol Pharmacol; 1994 Sep; 46(3):568-77. PubMed ID: 7935340
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cloning and functional expression of a novel marmoset cytochrome P450 2D enzyme, CYP2D30: comparison with the known marmoset CYP2D19.
    Hichiya H; Kuramoto S; Yamamoto S; Shinoda S; Hanioka N; Narimatsu S; Asaoka K; Miyata A; Iwata S; Nomoto M; Satoh T; Kiryu K; Ueda N; Naito S; Tucker GT; Ellis SW
    Biochem Pharmacol; 2004 Jul; 68(1):165-75. PubMed ID: 15183128
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular Cloning, Tissue Distribution, and Functional Characterization of Marmoset Cytochrome P450 1A1, 1A2, and 1B1.
    Uehara S; Uno Y; Inoue T; Sasaki E; Yamazaki H
    Drug Metab Dispos; 2016 Jan; 44(1):8-15. PubMed ID: 26502772
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Strong Induction of Cytochrome P450 1A/3A, But not P450 2B, in Cultured Hepatocytes from Common Marmosets and Cynomolgus Monkeys by Typical Human P450 Inducing Agents.
    Uehara S; Uno Y; Suzuki T; Inoue T; Utoh M; Sasaki E; Yamazaki H
    Drug Metab Lett; 2017; 10(4):244-253. PubMed ID: 27842484
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.