BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

313 related articles for article (PubMed ID: 28502980)

  • 1. W2476 ameliorates β-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via modulation of the thioredoxin-interacting protein signaling pathway.
    Li T; Lin GY; Zhong L; Zhou Y; Wang J; Zhu Y; Feng Y; Cai XQ; Liu Q; Nosjean O; Boutin JA; Renard P; Yang DH; Wang MW
    Acta Pharmacol Sin; 2017 Jul; 38(7):1024-1037. PubMed ID: 28502980
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Adenine derivatives invert high glucose-induced thioredoxin-interacting protein overexpression.
    Zhong L; Liu Q; Ting YS; Thien VY; Binti Kalong NS; Yang D; Wang MW
    Chem Biol Drug Des; 2018 Dec; 92(6):1998-2008. PubMed ID: 30043441
    [TBL] [Abstract][Full Text] [Related]  

  • 3. High beta-cell mass prevents streptozotocin-induced diabetes in thioredoxin-interacting protein-deficient mice.
    Masson E; Koren S; Razik F; Goldberg H; Kwan EP; Sheu L; Gaisano HY; Fantus IG
    Am J Physiol Endocrinol Metab; 2009 Jun; 296(6):E1251-61. PubMed ID: 19223654
    [TBL] [Abstract][Full Text] [Related]  

  • 4. W2476 represses TXNIP transcription via dephosphorylation of FOXO1 at Ser319.
    Zhong L; Liu Q; Liu Q; Zhang S; Cao Y; Yang D; Wang MW
    Chem Biol Drug Des; 2021 May; 97(5):1089-1099. PubMed ID: 33560565
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Preventing β-cell loss and diabetes with calcium channel blockers.
    Xu G; Chen J; Jing G; Shalev A
    Diabetes; 2012 Apr; 61(4):848-56. PubMed ID: 22442301
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insulin counteracts glucotoxic effects by suppressing thioredoxin-interacting protein production in INS-1E beta cells and in Psammomys obesus pancreatic islets.
    Shaked M; Ketzinel-Gilad M; Ariav Y; Cerasi E; Kaiser N; Leibowitz G
    Diabetologia; 2009 Apr; 52(4):636-44. PubMed ID: 19214472
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cytokines Regulate β-Cell Thioredoxin-interacting Protein (TXNIP) via Distinct Mechanisms and Pathways.
    Hong K; Xu G; Grayson TB; Shalev A
    J Biol Chem; 2016 Apr; 291(16):8428-39. PubMed ID: 26858253
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis.
    Chen J; Saxena G; Mungrue IN; Lusis AJ; Shalev A
    Diabetes; 2008 Apr; 57(4):938-44. PubMed ID: 18171713
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SIRT6-mediated transcriptional suppression of Txnip is critical for pancreatic beta cell function and survival in mice.
    Qin K; Zhang N; Zhang Z; Nipper M; Zhu Z; Leighton J; Xu K; Musi N; Wang P
    Diabetologia; 2018 Apr; 61(4):906-918. PubMed ID: 29322219
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transcription factor Ets1 regulates expression of thioredoxin-interacting protein and inhibits insulin secretion in pancreatic β-cells.
    Luo Y; He F; Hu L; Hai L; Huang M; Xu Z; Zhang J; Zhou Z; Liu F; Dai YS
    PLoS One; 2014; 9(6):e99049. PubMed ID: 24897113
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes.
    Chen J; Hui ST; Couto FM; Mungrue IN; Davis DB; Attie AD; Lusis AJ; Davis RA; Shalev A
    FASEB J; 2008 Oct; 22(10):3581-94. PubMed ID: 18552236
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lack of TXNIP protects beta-cells against glucotoxicity.
    Shalev A
    Biochem Soc Trans; 2008 Oct; 36(Pt 5):963-5. PubMed ID: 18793170
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Thioredoxin-interacting protein regulates insulin transcription through microRNA-204.
    Xu G; Chen J; Jing G; Shalev A
    Nat Med; 2013 Sep; 19(9):1141-6. PubMed ID: 23975026
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TXNIP, a novel key factor to cause Schwann cell dysfunction in diabetic peripheral neuropathy, under the regulation of PI3K/Akt pathway inhibition-induced DNMT1 and DNMT3a overexpression.
    Zhang X; Zhao S; Yuan Q; Zhu L; Li F; Wang H; Kong D; Hao J
    Cell Death Dis; 2021 Jun; 12(7):642. PubMed ID: 34162834
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300, and histone H4 acetylation in pancreatic beta cells.
    Cha-Molstad H; Saxena G; Chen J; Shalev A
    J Biol Chem; 2009 Jun; 284(25):16898-16905. PubMed ID: 19411249
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Deletion of thioredoxin-interacting protein improves cardiac inotropic reserve in the streptozotocin-induced diabetic heart.
    Myers RB; Fomovsky GM; Lee S; Tan M; Wang BF; Patwari P; Yoshioka J
    Am J Physiol Heart Circ Physiol; 2016 Jun; 310(11):H1748-59. PubMed ID: 27037370
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Palmitate and insulin counteract glucose-induced thioredoxin interacting protein (TXNIP) expression in insulin secreting cells via distinct mechanisms.
    Panse M; Kluth O; Lorza-Gil E; Kaiser G; Mühlbauer E; Schürmann A; Häring HU; Ullrich S; Gerst F
    PLoS One; 2018; 13(5):e0198016. PubMed ID: 29813102
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alpha Cell Thioredoxin-interacting Protein Deletion Improves Diabetes-associated Hyperglycemia and Hyperglucagonemia.
    Lu B; Chen J; Xu G; Grayson TB; Jing G; Jo S; Shalev A
    Endocrinology; 2022 Oct; 163(11):. PubMed ID: 35957590
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid-induced ER stress-mediated beta-cell death.
    Chen J; Fontes G; Saxena G; Poitout V; Shalev A
    Diabetes; 2010 Feb; 59(2):440-7. PubMed ID: 19875615
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of histone acetyltransferase by naringenin and hesperetin suppresses Txnip expression and protects pancreatic β cells in diabetic mice.
    Wang SW; Sheng H; Bai YF; Weng YY; Fan XY; Zheng F; Fu JQ; Zhang F
    Phytomedicine; 2021 Jul; 88():153454. PubMed ID: 33663922
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.