BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

487 related articles for article (PubMed ID: 28511073)

  • 1. Preparation and evaluation of L- and D-5-[
    Tang T; Gill HS; Ogasawara A; Tinianow JN; Vanderbilt AN; Williams SP; Hatzivassiliou G; White S; Sandoval W; DeMent K; Wong M; Marik J
    Nucl Med Biol; 2017 Aug; 51():10-17. PubMed ID: 28511073
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fully automated radiosynthesis of N(1)-[(18)F]fluoroethyl-tryptophan and study of its biological activity as a new potential substrate for indoleamine 2,3-dioxygenase PET imaging.
    Henrottin J; Lemaire C; Egrise D; Zervosen A; Van den Eynde B; Plenevaux A; Franci X; Goldman S; Luxen A
    Nucl Med Biol; 2016 Jun; 43(6):379-89. PubMed ID: 27260779
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Improved Radiosynthesis and Biological Evaluations of L- and D-1-[
    Xin Y; Cai H
    Mol Imaging Biol; 2017 Aug; 19(4):589-598. PubMed ID: 27815661
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting the IDO1/TDO2-KYN-AhR Pathway for Cancer Immunotherapy - Challenges and Opportunities.
    Cheong JE; Sun L
    Trends Pharmacol Sci; 2018 Mar; 39(3):307-325. PubMed ID: 29254698
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of indoleamine-2,3-dioxygenase 1, tryptophan-2,3-dioxygenase, and Ido1/Tdo2 knockout mice.
    Aslamkhan AG; Xu Q; Loughlin A; Vu H; Pacchione S; Bhatt B; Garfinkel I; Styring TG; LaFranco-Scheuch L; Pearson K; Reynolds S; Li N; Zhou H; Miller JR; Solban N; Bass A; Glaab WE
    Toxicol Appl Pharmacol; 2020 Nov; 406():115216. PubMed ID: 32871117
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery and Characterisation of Dual Inhibitors of Tryptophan 2,3-Dioxygenase (TDO2) and Indoleamine 2,3-Dioxygenase 1 (IDO1) Using Virtual Screening.
    Sari S; Tomek P; Leung E; Reynisson J
    Molecules; 2019 Nov; 24(23):. PubMed ID: 31795096
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fluorine-18-Labeled PET Radiotracers for Imaging Tryptophan Uptake and Metabolism: a Systematic Review.
    John F; Muzik O; Mittal S; Juhász C
    Mol Imaging Biol; 2020 Aug; 22(4):805-819. PubMed ID: 31512038
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A highly efficient modality to block the degradation of tryptophan for cancer immunotherapy: locked nucleic acid-modified antisense oligonucleotides to inhibit human indoleamine 2,3-dioxygenase 1/tryptophan 2,3-dioxygenase expression.
    Klar R; Michel S; Schell M; Hinterwimmer L; Zippelius A; Jaschinski F
    Cancer Immunol Immunother; 2020 Jan; 69(1):57-67. PubMed ID: 31802183
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Deletion of TDO2, IDO-1 and IDO-2 differentially affects mouse behavior and cognitive function.
    Too LK; Li KM; Suarna C; Maghzal GJ; Stocker R; McGregor IS; Hunt NH
    Behav Brain Res; 2016 Oct; 312():102-17. PubMed ID: 27316339
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evaluation of Novel Inhibitors of Tryptophan Dioxygenases for Enzyme and Species Selectivity Using Engineered Tumour Cell Lines Expressing Either Murine or Human IDO1 or TDO2.
    Tijono SM; Palmer BD; Tomek P; Flanagan JU; Henare K; Gamage S; Braun L; Ching LM
    Pharmaceuticals (Basel); 2022 Aug; 15(9):. PubMed ID: 36145311
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Preclinical investigations and a first-in-human phase I trial of M4112, the first dual inhibitor of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase 2, in patients with advanced solid tumors.
    Naing A; Eder JP; Piha-Paul SA; Gimmi C; Hussey E; Zhang S; Hildebrand V; Hosagrahara V; Habermehl C; Moisan J; Papadopoulos KP
    J Immunother Cancer; 2020 Aug; 8(2):. PubMed ID: 32843490
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Radiosynthesis and biological evaluation of 5-(3-[18F]fluoropropyloxy)-L-tryptophan for tumor PET imaging.
    He S; Tang G; Hu K; Wang H; Wang S; Huang T; Liang X; Tang X
    Nucl Med Biol; 2013 Aug; 40(6):801-7. PubMed ID: 23791401
    [TBL] [Abstract][Full Text] [Related]  

  • 13. IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism.
    Löb S; Königsrainer A; Zieker D; Brücher BL; Rammensee HG; Opelz G; Terness P
    Cancer Immunol Immunother; 2009 Jan; 58(1):153-7. PubMed ID: 18418598
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tryptophan catabolism is dysregulated in leiomyomas.
    Chuang TD; Quintanilla D; Boos D; Khorram O
    Fertil Steril; 2021 Oct; 116(4):1160-1171. PubMed ID: 34116832
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Indoleamine 2,3-dioxygenase 1 deficiency attenuates CCl4-induced fibrosis through Th17 cells down-regulation and tryptophan 2,3-dioxygenase compensation.
    Zhong W; Gao L; Zhou Z; Lin H; Chen C; Huang P; Huang W; Zhou C; Huang S; Nie L; Liu Y; Chen Y; Zhou D; Lv Z
    Oncotarget; 2017 Jun; 8(25):40486-40500. PubMed ID: 28465467
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Age-dependent alterations of the kynurenine pathway in the YAC128 mouse model of Huntington disease.
    Mazarei G; Budac DP; Lu G; Adomat H; Tomlinson Guns ES; Möller T; Leavitt BR
    J Neurochem; 2013 Dec; 127(6):852-67. PubMed ID: 23786539
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization and evolution of vertebrate indoleamine 2, 3-dioxygenases IDOs from monotremes and marsupials.
    Yuasa HJ; Ball HJ; Ho YF; Austin CJ; Whittington CM; Belov K; Maghzal GJ; Jermiin LS; Hunt NH
    Comp Biochem Physiol B Biochem Mol Biol; 2009 Jun; 153(2):137-44. PubMed ID: 19402226
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tryptophan: A Rheostat of Cancer Immune Escape Mediated by Immunosuppressive Enzymes IDO1 and TDO.
    Kim M; Tomek P
    Front Immunol; 2021; 12():636081. PubMed ID: 33708223
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Imaging tryptophan uptake with positron emission tomography in glioblastoma patients treated with indoximod.
    Lukas RV; Juhász C; Wainwright DA; James CD; Kennedy E; Stupp R; Lesniak MS
    J Neurooncol; 2019 Jan; 141(1):111-120. PubMed ID: 30415456
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and evaluation of 6-[18F]fluoro-3-(pyridin-3-yl)-1H-indole as potential PET tracer for targeting tryptophane 2, 3-dioxygenase (TDO).
    Qiao Z; Mardon K; Stimson DHR; Migotto MA; Reutens DC; Bhalla R
    Nucl Med Biol; 2020; 84-85():1-10. PubMed ID: 31927462
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.