These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

468 related articles for article (PubMed ID: 28512002)

  • 1. Cell-surface G-protein-coupled receptors for tumor-associated metabolites: A direct link to mitochondrial dysfunction in cancer.
    Ristic B; Bhutia YD; Ganapathy V
    Biochim Biophys Acta Rev Cancer; 2017 Aug; 1868(1):246-257. PubMed ID: 28512002
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sirtuin 3 (SIRT3) Regulates α-Smooth Muscle Actin (α-SMA) Production through the Succinate Dehydrogenase-G Protein-coupled Receptor 91 (GPR91) Pathway in Hepatic Stellate Cells.
    Li YH; Choi DH; Lee EH; Seo SR; Lee S; Cho EH
    J Biol Chem; 2016 May; 291(19):10277-92. PubMed ID: 26912655
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Succinate accumulation impairs cardiac pyruvate dehydrogenase activity through GRP91-dependent and independent signaling pathways: Therapeutic effects of ginsenoside Rb1.
    Li J; Yang YL; Li LZ; Zhang L; Liu Q; Liu K; Li P; Liu B; Qi LW
    Biochim Biophys Acta Mol Basis Dis; 2017 Nov; 1863(11):2835-2847. PubMed ID: 28736181
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Succinate causes α-SMA production through GPR91 activation in hepatic stellate cells.
    Li YH; Woo SH; Choi DH; Cho EH
    Biochem Biophys Res Commun; 2015 Aug; 463(4):853-8. PubMed ID: 26051274
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of high fat diet on GPR109A and GPR81 gene expression.
    Wanders D; Graff EC; Judd RL
    Biochem Biophys Res Commun; 2012 Aug; 425(2):278-83. PubMed ID: 22842580
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acetoacetate and beta-hydroxybutyrate in combination with other metabolites release insulin from INS-1 cells and provide clues about pathways in insulin secretion.
    MacDonald MJ; Longacre MJ; Stoker SW; Brown LJ; Hasan NM; Kendrick MA
    Am J Physiol Cell Physiol; 2008 Feb; 294(2):C442-50. PubMed ID: 18160486
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Succinate induces aberrant mitochondrial fission in cardiomyocytes through GPR91 signaling.
    Lu YT; Li LZ; Yang YL; Yin X; Liu Q; Zhang L; Liu K; Liu B; Li J; Qi LW
    Cell Death Dis; 2018 Jun; 9(6):672. PubMed ID: 29867110
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lactate/GPR81 signaling and proton motive force in cancer: Role in angiogenesis, immune escape, nutrition, and Warburg phenomenon.
    Brown TP; Ganapathy V
    Pharmacol Ther; 2020 Feb; 206():107451. PubMed ID: 31836453
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitochondrial metabolism of pyruvate in bovine spermatozoa.
    Hutson SM; Van Dop C; Lardy HA
    J Biol Chem; 1977 Feb; 252(4):1309-15. PubMed ID: 838719
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production.
    Shimazu T; Hirschey MD; Hua L; Dittenhafer-Reed KE; Schwer B; Lombard DB; Li Y; Bunkenborg J; Alt FW; Denu JM; Jacobson MP; Verdin E
    Cell Metab; 2010 Dec; 12(6):654-61. PubMed ID: 21109197
    [TBL] [Abstract][Full Text] [Related]  

  • 11. GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon.
    Thangaraju M; Cresci GA; Liu K; Ananth S; Gnanaprakasam JP; Browning DD; Mellinger JD; Smith SB; Digby GJ; Lambert NA; Prasad PD; Ganapathy V
    Cancer Res; 2009 Apr; 69(7):2826-32. PubMed ID: 19276343
    [TBL] [Abstract][Full Text] [Related]  

  • 12. GPR109A, GPR109B and GPR81, a family of hydroxy-carboxylic acid receptors.
    Ahmed K; Tunaru S; Offermanns S
    Trends Pharmacol Sci; 2009 Nov; 30(11):557-62. PubMed ID: 19837462
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gerometabolites: the pseudohypoxic aging side of cancer oncometabolites.
    Menendez JA; Alarcón T; Joven J
    Cell Cycle; 2014; 13(5):699-709. PubMed ID: 24526120
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oncometabolite succinate promotes angiogenesis by upregulating VEGF expression through GPR91-mediated STAT3 and ERK activation.
    Mu X; Zhao T; Xu C; Shi W; Geng B; Shen J; Zhang C; Pan J; Yang J; Hu S; Lv Y; Wen H; You Q
    Oncotarget; 2017 Feb; 8(8):13174-13185. PubMed ID: 28061458
    [TBL] [Abstract][Full Text] [Related]  

  • 15. G-protein-coupled receptor 91 and succinate are key contributors in neonatal postcerebral hypoxia-ischemia recovery.
    Hamel D; Sanchez M; Duhamel F; Roy O; Honoré JC; Noueihed B; Zhou T; Nadeau-Vallée M; Hou X; Lavoie JC; Mitchell G; Mamer OA; Chemtob S
    Arterioscler Thromb Vasc Biol; 2014 Feb; 34(2):285-93. PubMed ID: 24285580
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pyruvate Dehydrogenase and Tricarboxylic Acid Cycle Enzymes Are Sensitive Targets of Traumatic Brain Injury Induced Metabolic Derangement.
    Lazzarino G; Amorini AM; Signoretti S; Musumeci G; Lazzarino G; Caruso G; Pastore FS; Di Pietro V; Tavazzi B; Belli A
    Int J Mol Sci; 2019 Nov; 20(22):. PubMed ID: 31744143
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enzymes involved in l-lactate metabolism in humans.
    Adeva M; González-Lucán M; Seco M; Donapetry C
    Mitochondrion; 2013 Nov; 13(6):615-29. PubMed ID: 24029012
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MicroRNA-195 Regulates Metabolism in Failing Myocardium Via Alterations in Sirtuin 3 Expression and Mitochondrial Protein Acetylation.
    Zhang X; Ji R; Liao X; Castillero E; Kennel PJ; Brunjes DL; Franz M; Möbius-Winkler S; Drosatos K; George I; Chen EI; Colombo PC; Schulze PC
    Circulation; 2018 May; 137(19):2052-2067. PubMed ID: 29330215
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Peroxisome proliferator-activated receptor gamma regulates expression of the anti-lipolytic G-protein-coupled receptor 81 (GPR81/Gpr81).
    Jeninga EH; Bugge A; Nielsen R; Kersten S; Hamers N; Dani C; Wabitsch M; Berger R; Stunnenberg HG; Mandrup S; Kalkhoven E
    J Biol Chem; 2009 Sep; 284(39):26385-93. PubMed ID: 19633298
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation.
    Jing E; O'Neill BT; Rardin MJ; Kleinridders A; Ilkeyeva OR; Ussar S; Bain JR; Lee KY; Verdin EM; Newgard CB; Gibson BW; Kahn CR
    Diabetes; 2013 Oct; 62(10):3404-17. PubMed ID: 23835326
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.