BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 28521262)

  • 1. Rhodium-catalyzed C-H bond activation for the synthesis of quinonoid compounds: Significant Anti-Trypanosoma cruzi activities and electrochemical studies of functionalized quinones.
    Jardim GAM; Silva TL; Goulart MOF; de Simone CA; Barbosa JMC; Salomão K; de Castro SL; Bower JF; da Silva Júnior EN
    Eur J Med Chem; 2017 Aug; 136():406-419. PubMed ID: 28521262
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ruthenium(II)- and Palladium(II)-catalyzed position-divergent CH oxygenations of arylated quinones: Identification of hydroxylated quinonoid compounds with potent trypanocidal activity.
    Gontijo TB; de Carvalho RL; Dantas-Pereira L; Menna-Barreto RFS; Rogge T; Ackermann L; da Silva Júnior EN
    Bioorg Med Chem; 2021 Jun; 40():116164. PubMed ID: 34020276
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological evaluation of quinones derived from natural product komaroviquinone as anti-Trypanosoma cruzi agents.
    Suto Y; Nakajima-Shimada J; Yamagiwa N; Onizuka Y; Iwasaki G
    Bioorg Med Chem Lett; 2015 Aug; 25(15):2967-71. PubMed ID: 26037321
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Strategies towards potent trypanocidal drugs: Application of Rh-catalyzed [2 + 2 + 2] cycloadditions, sulfonyl phthalide annulation and nitroalkene reactions for the synthesis of substituted quinones and their evaluation against Trypanosoma cruzi.
    Wood JM; Satam NS; Almeida RG; Cristani VS; de Lima DP; Dantas-Pereira L; Salomão K; Menna-Barreto RFS; Namboothiri INN; Bower JF; da Silva Júnior EN
    Bioorg Med Chem; 2020 Aug; 28(15):115565. PubMed ID: 32631558
    [TBL] [Abstract][Full Text] [Related]  

  • 5. New benzimidazolequinones as trypanosomicidal agents.
    López-Lira C; Tapia RA; Herrera A; Lapier M; Maya JD; Soto-Delgado J; Oliver AG; Graham Lappin A; Uriarte E
    Bioorg Chem; 2021 Jun; 111():104823. PubMed ID: 33798844
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and anti-Trypanosoma cruzi activity of naphthoquinone-containing triazoles: electrochemical studies on the effects of the quinoidal moiety.
    Diogo EB; Dias GG; Rodrigues BL; Guimarães TT; Valença WO; Camara CA; de Oliveira RN; da Silva MG; Ferreira VF; de Paiva YG; Goulart MO; Menna-Barreto RF; de Castro SL; da Silva Júnior EN
    Bioorg Med Chem; 2013 Nov; 21(21):6337-48. PubMed ID: 24074878
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural design, synthesis and pharmacological evaluation of thiazoles against Trypanosoma cruzi.
    de Oliveira Filho GB; Cardoso MVO; Espíndola JWP; Oliveira E Silva DA; Ferreira RS; Coelho PL; Anjos PSD; Santos ES; Meira CS; Moreira DRM; Soares MBP; Leite ACL
    Eur J Med Chem; 2017 Dec; 141():346-361. PubMed ID: 29031078
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Efficacy of 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinone derivatives against different Trypanosoma cruzi discrete type units: Identification of a promising hit compound.
    Lara LS; Moreira CS; Calvet CM; Lechuga GC; Souza RS; Bourguignon SC; Ferreira VF; Rocha D; Pereira MCS
    Eur J Med Chem; 2018 Jan; 144():572-581. PubMed ID: 29289882
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display trypanocidal activity.
    Uliassi E; Fiorani G; Krauth-Siegel RL; Bergamini C; Fato R; Bianchini G; Carlos Menéndez J; Molina MT; López-Montero E; Falchi F; Cavalli A; Gul S; Kuzikov M; Ellinger B; Witt G; Moraes CB; Freitas-Junior LH; Borsari C; Costi MP; Bolognesi ML
    Eur J Med Chem; 2017 Dec; 141():138-148. PubMed ID: 29031061
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi.
    da Silva EN; Menna-Barreto RF; Pinto Mdo C; Silva RS; Teixeira DV; de Souza MC; De Simone CA; De Castro SL; Ferreira VF; Pinto AV
    Eur J Med Chem; 2008 Aug; 43(8):1774-80. PubMed ID: 18045742
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of naphthofuranquinones with activity against Trypanosoma cruzi.
    Silva RS; Costa EM; Trindade UL; Teixeira DV; Pinto Mde C; Santos GL; Malta VR; De Simone CA; Pinto AV; de Castro SL
    Eur J Med Chem; 2006 Apr; 41(4):526-30. PubMed ID: 16500733
    [TBL] [Abstract][Full Text] [Related]  

  • 12. New aryloxy-quinone derivatives with promising activity on Trypanosoma cruzi.
    Espinosa-Bustos C; Vázquez K; Varela J; Cerecetto H; Paulino M; Segura R; Pizarro J; Vera B; González M; Zarate AM; Salas CO
    Arch Pharm (Weinheim); 2020 Jan; 353(1):e1900213. PubMed ID: 31709599
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combination of Aryl Diselenides/Hydrogen Peroxide and Carbon-Nanotube/Rhodium Nanohybrids for Naphthol Oxidation: An Efficient Route towards Trypanocidal Quinones.
    de Carvalho RL; Jardim GAM; Santos ACC; Araujo MH; Oliveira WXC; Bombaça ACS; Menna-Barreto RFS; Gopi E; Gravel E; Doris E; da Silva Júnior EN
    Chemistry; 2018 Oct; 24(57):15227-15235. PubMed ID: 29904959
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and in vitro trypanocide activity of several polycyclic drimane-quinone derivatives.
    Cuellar MA; Salas C; Cortés MJ; Morello A; Diego Maya J; Preite MD
    Bioorg Med Chem; 2003 Jun; 11(12):2489-97. PubMed ID: 12757716
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of New Thiosemicarbazones and Semicarbazones Containing the 1,2,3-1H-triazole-isatin Scaffold: Trypanocidal, Cytotoxicity, Electrochemical Assays, and Molecular Docking.
    Silva BNM; Sales Junior PA; Romanha AJ; Murta SMF; Lima CHS; Albuquerque MG; D'Elia E; Rodrigues JGA; Ferreira VF; Silva FC; Pinto AC; Silva BV
    Med Chem; 2019; 15(3):240-256. PubMed ID: 30332972
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Trypanosoma cruzi: activities of lapachol and alpha- and beta-lapachone derivatives against epimastigote and trypomastigote forms.
    Salas C; Tapia RA; Ciudad K; Armstrong V; Orellana M; Kemmerling U; Ferreira J; Maya JD; Morello A
    Bioorg Med Chem; 2008 Jan; 16(2):668-74. PubMed ID: 18029184
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 2-Phenylaminonaphthoquinones and related compounds: synthesis, trypanocidal and cytotoxic activities.
    Sieveking I; Thomas P; Estévez JC; Quiñones N; Cuéllar MA; Villena J; Espinosa-Bustos C; Fierro A; Tapia RA; Maya JD; López-Muñoz R; Cassels BK; Estévez RJ; Salas CO
    Bioorg Med Chem; 2014 Sep; 22(17):4609-20. PubMed ID: 25127463
    [TBL] [Abstract][Full Text] [Related]  

  • 18. On the search for potential anti-Trypanosoma cruzi drugs: synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions.
    da Silva Júnior EN; de Melo IM; Diogo EB; Costa VA; de Souza Filho JD; Valença WO; Camara CA; de Oliveira RN; de Araujo AS; Emery FS; dos Santos MR; de Simone CA; Menna-Barreto RF; de Castro SL
    Eur J Med Chem; 2012 Jun; 52():304-12. PubMed ID: 22483633
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Natural and synthetic naphthoquinones active against Trypanosoma cruzi: an initial step towards new drugs for Chagas disease.
    Salas CO; Faúndez M; Morello A; Maya JD; Tapia RA
    Curr Med Chem; 2011; 18(1):144-61. PubMed ID: 21110810
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological evaluation of 2-methyl-1H-benzimidazole-5-carbohydrazides derivatives as modifiers of redox homeostasis of Trypanosoma cruzi.
    Melchor-Doncel de la Torre S; Vázquez C; González-Chávez Z; Yépez-Mulia L; Nieto-Meneses R; Jasso-Chávez R; Saavedra E; Hernández-Luis F
    Bioorg Med Chem Lett; 2017 Aug; 27(15):3403-3407. PubMed ID: 28648464
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.