BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

581 related articles for article (PubMed ID: 28521333)

  • 1. Drugging the Cancers Addicted to DNA Repair.
    Nickoloff JA; Jones D; Lee SH; Williamson EA; Hromas R
    J Natl Cancer Inst; 2017 Nov; 109(11):. PubMed ID: 28521333
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Biomarker-Guided Development of DNA Repair Inhibitors.
    Cleary JM; Aguirre AJ; Shapiro GI; D'Andrea AD
    Mol Cell; 2020 Jun; 78(6):1070-1085. PubMed ID: 32459988
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gynecologic Cancers: Emerging Novel Strategies for Targeting DNA Repair Deficiency.
    Kristeleit RS; Miller RE; Kohn EC
    Am Soc Clin Oncol Educ Book; 2016; 35():e259-68. PubMed ID: 27249731
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New Targeted Agents in Gynecologic Cancers: Synthetic Lethality, Homologous Recombination Deficiency, and PARP Inhibitors.
    Liu FW; Tewari KS
    Curr Treat Options Oncol; 2016 Mar; 17(3):12. PubMed ID: 26931795
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Abnormalities of DNA repair and gynecological cancers].
    Auguste A; Leary A
    Bull Cancer; 2017 Nov; 104(11):971-980. PubMed ID: 29054544
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers.
    Srinivasan G; Williamson EA; Kong K; Jaiswal AS; Huang G; Kim HS; Schärer O; Zhao W; Burma S; Sung P; Hromas R
    Proc Natl Acad Sci U S A; 2019 Aug; 116(35):17438-17443. PubMed ID: 31395736
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination.
    Guo E; Ishii Y; Mueller J; Srivatsan A; Gahman T; Putnam CD; Wang JYJ; Kolodner RD
    Proc Natl Acad Sci U S A; 2020 Aug; 117(32):19415-19424. PubMed ID: 32719125
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthetic lethality in DNA repair network: A novel avenue in targeted cancer therapy and combination therapeutics.
    Bhattacharjee S; Nandi S
    IUBMB Life; 2017 Dec; 69(12):929-937. PubMed ID: 29171189
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The endonuclease EEPD1 mediates synthetic lethality in RAD52-depleted BRCA1 mutant breast cancer cells.
    Hromas R; Kim HS; Sidhu G; Williamson E; Jaiswal A; Totterdale TA; Nole J; Lee SH; Nickoloff JA; Kong KY
    Breast Cancer Res; 2017 Nov; 19(1):122. PubMed ID: 29145865
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PARP inhibitors: Synthetic lethality in the clinic.
    Lord CJ; Ashworth A
    Science; 2017 Mar; 355(6330):1152-1158. PubMed ID: 28302823
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [From poly(ADP-ribose) discovery to PARP inhibitors in cancer therapy].
    Schreiber V; Illuzzi G; Héberlé E; Dantzer F
    Bull Cancer; 2015 Oct; 102(10):863-73. PubMed ID: 26384693
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthetic lethality of PARP inhibition in cancers lacking BRCA1 and BRCA2 mutations.
    Dedes KJ; Wilkerson PM; Wetterskog D; Weigelt B; Ashworth A; Reis-Filho JS
    Cell Cycle; 2011 Apr; 10(8):1192-9. PubMed ID: 21487248
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair.
    Ashworth A
    J Clin Oncol; 2008 Aug; 26(22):3785-90. PubMed ID: 18591545
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [DNA repair as a therapeutic target].
    Eberst L; Brahmi M; Cassier PA
    Bull Cancer; 2017 Nov; 104(11):988-998. PubMed ID: 29132681
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PARP inhibitors in breast cancer: Bringing synthetic lethality to the bedside.
    Turk AA; Wisinski KB
    Cancer; 2018 Jun; 124(12):2498-2506. PubMed ID: 29660759
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthetic lethality in malignant pleural mesothelioma with PARP1 inhibition.
    Srinivasan G; Sidhu GS; Williamson EA; Jaiswal AS; Najmunnisa N; Wilcoxen K; Jones D; George TJ; Hromas R
    Cancer Chemother Pharmacol; 2017 Oct; 80(4):861-867. PubMed ID: 28756516
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting DNA Repair in Cancer: Beyond PARP Inhibitors.
    Brown JS; O'Carrigan B; Jackson SP; Yap TA
    Cancer Discov; 2017 Jan; 7(1):20-37. PubMed ID: 28003236
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Poly(ADP-ribose) polymerase inhibitors in cancer treatment: a clinical perspective.
    Sandhu SK; Yap TA; de Bono JS
    Eur J Cancer; 2010 Jan; 46(1):9-20. PubMed ID: 19926276
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Molecular Mechanisms of Actions, Effects, and Clinical Implications of PARP Inhibitors in Epithelial Ovarian Cancers: A Systematic Review.
    Lau CH; Seow KM; Chen KH
    Int J Mol Sci; 2022 Jul; 23(15):. PubMed ID: 35897700
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crosstalk of DNA double-strand break repair pathways in poly(ADP-ribose) polymerase inhibitor treatment of breast cancer susceptibility gene 1/2-mutated cancer.
    Sunada S; Nakanishi A; Miki Y
    Cancer Sci; 2018 Apr; 109(4):893-899. PubMed ID: 29427345
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.