BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 28522590)

  • 1. Notch Inhibitor PF-03084014 Inhibits Hepatocellular Carcinoma Growth and Metastasis via Suppression of Cancer Stemness due to Reduced Activation of Notch1-Stat3.
    Wu CX; Xu A; Zhang CC; Olson P; Chen L; Lee TK; Cheung TT; Lo CM; Wang XQ
    Mol Cancer Ther; 2017 Aug; 16(8):1531-1543. PubMed ID: 28522590
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ZnAs@SiO
    Huang Y; Zhou B; Luo H; Mao J; Huang Y; Zhang K; Mei C; Yan Y; Jin H; Gao J; Su Z; Pang P; Li D; Shan H
    Theranostics; 2019; 9(15):4391-4408. PubMed ID: 31285768
    [No Abstract]   [Full Text] [Related]  

  • 3. Peroxiredoxin II Is Essential for Maintaining Stemness by Redox Regulation in Liver Cancer Cells.
    Kwon T; Bak Y; Park YH; Jang GB; Nam JS; Yoo JE; Park YN; Bak IS; Kim JM; Yoon DY; Yu DY
    Stem Cells; 2016 May; 34(5):1188-97. PubMed ID: 26866938
    [TBL] [Abstract][Full Text] [Related]  

  • 4. WM130 preferentially inhibits hepatic cancer stem-like cells by suppressing AKT/GSK3β/β-catenin signaling pathway.
    Ni CX; Qi Y; Zhang J; Liu Y; Xu WH; Xu J; Hu HG; Wu QY; Wang Y; Zhang JP
    Oncotarget; 2016 Nov; 7(48):79544-79556. PubMed ID: 27783993
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biomarker and pharmacologic evaluation of the γ-secretase inhibitor PF-03084014 in breast cancer models.
    Zhang CC; Pavlicek A; Zhang Q; Lira ME; Painter CL; Yan Z; Zheng X; Lee NV; Ozeck M; Qiu M; Zong Q; Lappin PB; Wong A; Rejto PA; Smeal T; Christensen JG
    Clin Cancer Res; 2012 Sep; 18(18):5008-19. PubMed ID: 22806875
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of selective gamma-secretase inhibitor PF-03084014 for its antitumor efficacy and gastrointestinal safety to guide optimal clinical trial design.
    Wei P; Walls M; Qiu M; Ding R; Denlinger RH; Wong A; Tsaparikos K; Jani JP; Hosea N; Sands M; Randolph S; Smeal T
    Mol Cancer Ther; 2010 Jun; 9(6):1618-28. PubMed ID: 20530712
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Coexpression of gene Oct4 and Nanog initiates stem cell characteristics in hepatocellular carcinoma and promotes epithelial-mesenchymal transition through activation of Stat3/Snail signaling.
    Yin X; Zhang BH; Zheng SS; Gao DM; Qiu SJ; Wu WZ; Ren ZG
    J Hematol Oncol; 2015 Mar; 8():23. PubMed ID: 25879771
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Smad inhibitor induces CSC differentiation for effective chemosensitization in cyclin D1- and TGF-β/Smad-regulated liver cancer stem cell-like cells.
    Xia W; Lo CM; Poon RYC; Cheung TT; Chan ACY; Chen L; Yang S; Tsao GSW; Wang XQ
    Oncotarget; 2017 Jun; 8(24):38811-38824. PubMed ID: 28415588
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Musashi2 contributes to the maintenance of CD44v6+ liver cancer stem cells via notch1 signaling pathway.
    Wang X; Wang R; Bai S; Xiong S; Li Y; Liu M; Zhao Z; Wang Y; Zhao Y; Chen W; Billiar TR; Cheng B
    J Exp Clin Cancer Res; 2019 Dec; 38(1):505. PubMed ID: 31888685
    [TBL] [Abstract][Full Text] [Related]  

  • 10. (-)-Oleocanthal inhibits growth and metastasis by blocking activation of STAT3 in human hepatocellular carcinoma.
    Pei T; Meng Q; Han J; Sun H; Li L; Song R; Sun B; Pan S; Liang D; Liu L
    Oncotarget; 2016 Jul; 7(28):43475-43491. PubMed ID: 27259268
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sphere-forming cell subpopulations with cancer stem cell properties in human hepatoma cell lines.
    Cao L; Zhou Y; Zhai B; Liao J; Xu W; Zhang R; Li J; Zhang Y; Chen L; Qian H; Wu M; Yin Z
    BMC Gastroenterol; 2011 Jun; 11():71. PubMed ID: 21669008
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gamma-secretase complex-dependent intramembrane proteolysis of CD147 regulates the Notch1 signaling pathway in hepatocellular carcinoma.
    Yong YL; Zhang RY; Liu ZK; Wei D; Shang YK; Wu J; Zhang ZY; Li C; Chen ZN; Bian H
    J Pathol; 2019 Oct; 249(2):255-267. PubMed ID: 31215640
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Disulfiram eradicates tumor-initiating hepatocellular carcinoma cells in ROS-p38 MAPK pathway-dependent and -independent manners.
    Chiba T; Suzuki E; Yuki K; Zen Y; Oshima M; Miyagi S; Saraya A; Koide S; Motoyama T; Ogasawara S; Ooka Y; Tawada A; Nakatsura T; Hayashi T; Yamashita T; Kaneko S; Miyazaki M; Iwama A; Yokosuka O
    PLoS One; 2014; 9(1):e84807. PubMed ID: 24454751
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Resolvin D1 prevents epithelial-mesenchymal transition and reduces the stemness features of hepatocellular carcinoma by inhibiting paracrine of cancer-associated fibroblast-derived COMP.
    Sun L; Wang Y; Wang L; Yao B; Chen T; Li Q; Liu Z; Liu R; Niu Y; Song T; Liu Q; Tu K
    J Exp Clin Cancer Res; 2019 Apr; 38(1):170. PubMed ID: 30999932
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Autophagy suppresses self-renewal ability and tumorigenicity of glioma-initiating cells and promotes Notch1 degradation.
    Tao Z; Li T; Ma H; Yang Y; Zhang C; Hai L; Liu P; Yuan F; Li J; Yi L; Tong L; Wang Y; Xie Y; Ming H; Yu S; Yang X
    Cell Death Dis; 2018 Oct; 9(11):1063. PubMed ID: 30337536
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 8-Bromo-7-methoxychrysin-blocked STAT3/Twist axis inhibits the stemness of cancer stem cell-like cell originated from SMMC-7721 cells.
    Luo Y; Cui Y; Cao X; Li X; Chen A; Zhang J; Chen X; Cao J
    Acta Biochim Biophys Sin (Shanghai); 2017 May; 49(5):458-464. PubMed ID: 28369327
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Combined treatment with sorafenib and silibinin synergistically targets both HCC cells and cancer stem cells by enhanced inhibition of the phosphorylation of STAT3/ERK/AKT.
    Mao J; Yang H; Cui T; Pan P; Kabir N; Chen D; Ma J; Chen X; Chen Y; Yang Y
    Eur J Pharmacol; 2018 Aug; 832():39-49. PubMed ID: 29782854
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Deubiquitinase inhibitor b-AP15 activates endoplasmic reticulum (ER) stress and inhibits Wnt/Notch1 signaling pathway leading to the reduction of cell survival in hepatocellular carcinoma cells.
    Ding Y; Chen X; Wang B; Yu B; Ge J
    Eur J Pharmacol; 2018 Apr; 825():10-18. PubMed ID: 29454609
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The neuroleptic drug pimozide inhibits stem-like cell maintenance and tumorigenicity in hepatocellular carcinoma.
    Chen JJ; Cai N; Chen GZ; Jia CC; Qiu DB; Du C; Liu W; Yang Y; Long ZJ; Zhang Q
    Oncotarget; 2017 Mar; 8(11):17593-17609. PubMed ID: 26061710
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of NOTCH signaling pathway chemosensitizes HCC CD133
    Hemati H; Kaur J; Sobti RC; Trehanpati N
    Biochem Biophys Res Commun; 2020 May; 525(4):941-947. PubMed ID: 32173531
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.