BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

257 related articles for article (PubMed ID: 28524854)

  • 1. A Smad3-PTEN regulatory loop controls proliferation and apoptotic responses to TGF-β in mouse endometrium.
    Eritja N; Felip I; Dosil MA; Vigezzi L; Mirantes C; Yeramian A; Navaridas R; Santacana M; Llobet-Navas D; Yoshimura A; Nomura M; Encinas M; Matias-Guiu X; Dolcet X
    Cell Death Differ; 2017 Aug; 24(8):1443-1458. PubMed ID: 28524854
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Loss of phosphatase and tensin homologue increases transforming growth factor beta-mediated invasion with enhanced SMAD3 transcriptional activity.
    Hjelmeland AB; Hjelmeland MD; Shi Q; Hart JL; Bigner DD; Wang XF; Kontos CD; Rich JN
    Cancer Res; 2005 Dec; 65(24):11276-81. PubMed ID: 16357132
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2.
    Song K; Cornelius SC; Reiss M; Danielpour D
    J Biol Chem; 2003 Oct; 278(40):38342-51. PubMed ID: 12876289
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TGF-β and Smad3 modulate PI3K/Akt signaling pathway in vascular smooth muscle cells.
    Suwanabol PA; Seedial SM; Zhang F; Shi X; Si Y; Liu B; Kent KC
    Am J Physiol Heart Circ Physiol; 2012 Jun; 302(11):H2211-9. PubMed ID: 22447946
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Akt interacts directly with Smad3 to regulate the sensitivity to TGF-beta induced apoptosis.
    Conery AR; Cao Y; Thompson EA; Townsend CM; Ko TC; Luo K
    Nat Cell Biol; 2004 Apr; 6(4):366-72. PubMed ID: 15104092
    [TBL] [Abstract][Full Text] [Related]  

  • 6. JQ1 suppresses tumor growth via PTEN/PI3K/AKT pathway in endometrial cancer.
    Qiu H; Li J; Clark LH; Jackson AL; Zhang L; Guo H; Kilgore JE; Gehrig PA; Zhou C; Bae-Jump VL
    Oncotarget; 2016 Oct; 7(41):66809-66821. PubMed ID: 27572308
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PTEN protects kidney against acute kidney injury by alleviating apoptosis and promoting autophagy via regulating HIF1-α and mTOR through PI3K/Akt pathway.
    Wang Y; Wang X; Wang H; Bao J; Jia N; Huang H; Li A
    Exp Cell Res; 2021 Sep; 406(1):112729. PubMed ID: 34242625
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protumorigenic actions of S100A2 involve regulation of PI3/Akt signaling and functional interaction with Smad3.
    Naz S; Bashir M; Ranganathan P; Bodapati P; Santosh V; Kondaiah P
    Carcinogenesis; 2014 Jan; 35(1):14-23. PubMed ID: 23996929
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Control of fibroblast fibronectin expression and alternative splicing via the PI3K/Akt/mTOR pathway.
    White ES; Sagana RL; Booth AJ; Yan M; Cornett AM; Bloomheart CA; Tsui JL; Wilke CA; Moore BB; Ritzenthaler JD; Roman J; Muro AF
    Exp Cell Res; 2010 Oct; 316(16):2644-53. PubMed ID: 20615404
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel roles of Akt and mTOR in suppressing TGF-beta/ALK5-mediated Smad3 activation.
    Song K; Wang H; Krebs TL; Danielpour D
    EMBO J; 2006 Jan; 25(1):58-69. PubMed ID: 16362038
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hepatocyte growth factor attenuates transforming growth factor-β-angiotensin II crosstalk through inhibition of the PTEN/Akt pathway.
    Iekushi K; Taniyama Y; Kusunoki H; Azuma J; Sanada F; Okayama K; Koibuchi N; Iwabayashi M; Rakugi H; Morishita R
    Hypertension; 2011 Aug; 58(2):190-6. PubMed ID: 21670418
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Loss of TGF-β signaling and PTEN promotes head and neck squamous cell carcinoma through cellular senescence evasion and cancer-related inflammation.
    Bian Y; Hall B; Sun ZJ; Molinolo A; Chen W; Gutkind JS; Waes CV; Kulkarni AB
    Oncogene; 2012 Jul; 31(28):3322-32. PubMed ID: 22037217
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PKB/Akt modulates TGF-beta signalling through a direct interaction with Smad3.
    Remy I; Montmarquette A; Michnick SW
    Nat Cell Biol; 2004 Apr; 6(4):358-65. PubMed ID: 15048128
    [TBL] [Abstract][Full Text] [Related]  

  • 14. (‑)‑Epigallocatechin‑3‑gallate induces apoptosis in human pancreatic cancer cells via PTEN.
    Liu S; Xu ZL; Sun L; Liu Y; Li CC; Li HM; Zhang W; Li CJ; Qin W
    Mol Med Rep; 2016 Jul; 14(1):599-605. PubMed ID: 27176210
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TNF-α impairs differentiation and function of TGF-β-induced Treg cells in autoimmune diseases through Akt and Smad3 signaling pathway.
    Zhang Q; Cui F; Fang L; Hong J; Zheng B; Zhang JZ
    J Mol Cell Biol; 2013 Apr; 5(2):85-98. PubMed ID: 23243069
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Loss of tumour suppressor PTEN expression in renal injury initiates SMAD3- and p53-dependent fibrotic responses.
    Samarakoon R; Helo S; Dobberfuhl AD; Khakoo NS; Falke L; Overstreet JM; Goldschmeding R; Higgins PJ
    J Pathol; 2015 Aug; 236(4):421-32. PubMed ID: 25810340
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TGF-β1 stimulates migration of type II endometrial cancer cells by down-regulating PTEN via activation of SMAD and ERK1/2 signaling pathways.
    Xiong S; Cheng JC; Klausen C; Zhao J; Leung PC
    Oncotarget; 2016 Sep; 7(38):61262-61272. PubMed ID: 27542208
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TGF-beta induces connexin43 gene expression in normal murine mammary gland epithelial cells via activation of p38 and PI3K/AKT signaling pathways.
    Tacheau C; Fontaine J; Loy J; Mauviel A; Verrecchia F
    J Cell Physiol; 2008 Dec; 217(3):759-68. PubMed ID: 18668519
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Upregulation of PTEN by peroxynitrite contributes to cytokine-induced apoptosis in pancreatic beta-cells.
    Hou R; Zhang J; Yin T; Cao H; Zhang N; Li X; Wang L; Xing Y; Li D; Ji Q
    Apoptosis; 2010 Aug; 15(8):877-86. PubMed ID: 20464496
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Potentiation of bortezomib-induced apoptosis by TGF-beta in cultured human Tenon's fibroblasts: contribution of the PI3K/Akt signaling pathway.
    Chung EJ; Moon SW; Jung SA; Cho YJ; Kim SW; Lee JH
    Invest Ophthalmol Vis Sci; 2010 Dec; 51(12):6232-7. PubMed ID: 20702821
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.