BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

255 related articles for article (PubMed ID: 28526921)

  • 1. GLP-1 signalling compensates for impaired insulin signalling in regulating beta cell proliferation in βIRKO mice.
    Kawamori D; Shirakawa J; Liew CW; Hu J; Morioka T; Duttaroy A; Burkey B; Kulkarni RN
    Diabetologia; 2017 Aug; 60(8):1442-1453. PubMed ID: 28526921
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DPP4 inhibitor vildagliptin preserves β-cell mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice.
    Shimizu S; Hosooka T; Matsuda T; Asahara S; Koyanagi-Kimura M; Kanno A; Bartolome A; Etoh H; Fuchita M; Teruyama K; Takahashi H; Inoue H; Mieda Y; Hashimoto N; Seino S; Kido Y
    J Mol Endocrinol; 2012 Oct; 49(2):125-35. PubMed ID: 22822047
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of long-term treatment with the dipeptidyl peptidase-4 inhibitor vildagliptin on islet endocrine cells in non-obese type 2 diabetic Goto-Kakizaki rats.
    Inaba W; Mizukami H; Kamata K; Takahashi K; Tsuboi K; Yagihashi S
    Eur J Pharmacol; 2012 Sep; 691(1-3):297-306. PubMed ID: 22820107
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Vildagliptin selectively ameliorates GLP-1, GLUT4, SREBP-1c mRNA levels and stimulates β-cell proliferation resulting in improved glucose homeostasis in rats with streptozotocin-induced diabetes.
    Akarte AS; Srinivasan BP; Gandhi S
    J Diabetes Complications; 2012; 26(4):266-74. PubMed ID: 22626875
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Impact of the dipeptidyl peptidase-4 inhibitor vildagliptin on glucose tolerance and β-cell function and mass in insulin receptor substrate-2-knockout mice fed a high-fat diet.
    Sato K; Nakamura A; Shirakawa J; Muraoka T; Togashi Y; Shinoda K; Orime K; Kubota N; Kadowaki T; Terauchi Y
    Endocrinology; 2012 Mar; 153(3):1093-102. PubMed ID: 22315446
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of dipeptidyl peptidase-4 by vildagliptin during glucagon-like Peptide 1 infusion increases liver glucose uptake in the conscious dog.
    Edgerton DS; Johnson KM; Neal DW; Scott M; Hobbs CH; Zhang X; Duttaroy A; Cherrington AD
    Diabetes; 2009 Jan; 58(1):243-9. PubMed ID: 18840785
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Vildagliptin stimulates endothelial cell network formation and ischemia-induced revascularization via an endothelial nitric-oxide synthase-dependent mechanism.
    Ishii M; Shibata R; Kondo K; Kambara T; Shimizu Y; Tanigawa T; Bando YK; Nishimura M; Ouchi N; Murohara T
    J Biol Chem; 2014 Sep; 289(39):27235-27245. PubMed ID: 25100725
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Beta-cell expression of a dominant-negative HNF-1alpha compromises the ability of inhibition of dipeptidyl peptidase-4 to elicit a long-term augmentation of insulin secretion in mice.
    Ahrén B; Sörhede Winzell M; Burkey B; Hughes TE
    Eur J Pharmacol; 2005 Oct; 521(1-3):164-8. PubMed ID: 16171801
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel long acting DPP-IV inhibitor PKF-275-055 stimulates β-cell proliferation resulting in improved glucose homeostasis in diabetic rats.
    Akarte AS; Srinivasan BP; Gandhi S
    Biochem Pharmacol; 2012 Jan; 83(2):241-52. PubMed ID: 22015634
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of GLP-1 and gastrin signalling induces in vivo reprogramming of pancreatic exocrine cells into beta cells in mice.
    Sasaki S; Miyatsuka T; Matsuoka TA; Takahara M; Yamamoto Y; Yasuda T; Kaneto H; Fujitani Y; German MS; Akiyama H; Watada H; Shimomura I
    Diabetologia; 2015 Nov; 58(11):2582-91. PubMed ID: 26290048
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glucagon-like peptide 1 prevents reactive oxygen species-induced endothelial cell senescence through the activation of protein kinase A.
    Oeseburg H; de Boer RA; Buikema H; van der Harst P; van Gilst WH; Silljé HH
    Arterioscler Thromb Vasc Biol; 2010 Jul; 30(7):1407-14. PubMed ID: 20448207
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Feedback suppression of meal-induced glucagon-like peptide-1 (GLP-1) secretion mediated through elevations in intact GLP-1 caused by dipeptidyl peptidase-4 inhibition: a randomized, prospective comparison of sitagliptin and vildagliptin treatment.
    Baranov O; Kahle M; Deacon CF; Holst JJ; Nauck MA
    Diabetes Obes Metab; 2016 Nov; 18(11):1100-1109. PubMed ID: 27300579
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DPP4-inhibitor improves neuronal insulin receptor function, brain mitochondrial function and cognitive function in rats with insulin resistance induced by high-fat diet consumption.
    Pipatpiboon N; Pintana H; Pratchayasakul W; Chattipakorn N; Chattipakorn SC
    Eur J Neurosci; 2013 Mar; 37(5):839-49. PubMed ID: 23240760
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of exendin-4 on glucose tolerance, insulin secretion, and beta-cell proliferation depend on treatment dose, treatment duration and meal contents.
    Arakawa M; Ebato C; Mita T; Hirose T; Kawamori R; Fujitani Y; Watada H
    Biochem Biophys Res Commun; 2009 Dec; 390(3):809-14. PubMed ID: 19836346
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dipeptidyl-peptidase IV inhibition improves pathophysiology of heart failure and increases survival rate in pressure-overloaded mice.
    Takahashi A; Asakura M; Ito S; Min KD; Shindo K; Yan Y; Liao Y; Yamazaki S; Sanada S; Asano Y; Ishibashi-Ueda H; Takashima S; Minamino T; Asanuma H; Mochizuki N; Kitakaze M
    Am J Physiol Heart Circ Physiol; 2013 May; 304(10):H1361-9. PubMed ID: 23504176
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DPP-4 inhibition improves glucose tolerance and increases insulin and GLP-1 responses to gastric glucose in association with normalized islet topography in mice with beta-cell-specific overexpression of human islet amyloid polypeptide.
    Ahrén B; Winzell MS; Wierup N; Sundler F; Burkey B; Hughes TE
    Regul Pept; 2007 Oct; 143(1-3):97-103. PubMed ID: 17482289
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Medicinal Chemistry of Incretin Mimetics and DPP-4 Inhibitors.
    Zettl H; Schubert-Zsilavecz M; Steinhilber D
    ChemMedChem; 2010 Feb; 5(2):179-85. PubMed ID: 20029928
    [No Abstract]   [Full Text] [Related]  

  • 18. Vildagliptin ameliorates oxidative stress and pancreatic beta cell destruction in type 1 diabetic rats.
    Ávila Dde L; Araújo GR; Silva M; Miranda PH; Diniz MF; Pedrosa ML; Silva ME; de Lima WG; Costa DC
    Arch Med Res; 2013 Apr; 44(3):194-202. PubMed ID: 23523961
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stimulation of pancreatic beta-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways.
    Friedrichsen BN; Neubauer N; Lee YC; Gram VK; Blume N; Petersen JS; Nielsen JH; Møldrup A
    J Endocrinol; 2006 Mar; 188(3):481-92. PubMed ID: 16522728
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Incretin receptors for glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide are essential for the sustained metabolic actions of vildagliptin in mice.
    Flock G; Baggio LL; Longuet C; Drucker DJ
    Diabetes; 2007 Dec; 56(12):3006-13. PubMed ID: 17717280
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.