These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Potent and prolonged acting cyclic lactam analogues of alpha-melanotropin: design based on molecular dynamics. Al-Obeidi F; Castrucci AM; Hadley ME; Hruby VJ J Med Chem; 1989 Dec; 32(12):2555-61. PubMed ID: 2555512 [TBL] [Abstract][Full Text] [Related]
3. Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors. Hruby VJ; Lu D; Sharma SD; Castrucci AL; Kesterson RA; al-Obeidi FA; Hadley ME; Cone RD J Med Chem; 1995 Sep; 38(18):3454-61. PubMed ID: 7658432 [TBL] [Abstract][Full Text] [Related]
4. Potent and prolonged melanotropic activities of the alpha-MSH fragment analog, Ac-[Nle4,D-Phe7]-alpha-MSH4-9-NH2. Klemes DG; Kreutzfeld KL; Hadley ME; Cody WL; Hruby VJ Biochem Biophys Res Commun; 1986 Jun; 137(2):722-8. PubMed ID: 3089218 [TBL] [Abstract][Full Text] [Related]
5. alpha-Melanotropin: the minimal active sequence in the frog skin bioassay. Hruby VJ; Wilkes BC; Hadley ME; Al-Obeidi F; Sawyer TK; Staples DJ; de Vaux AE; Dym O; Castrucci AM; Hintz MF J Med Chem; 1987 Nov; 30(11):2126-30. PubMed ID: 2822931 [TBL] [Abstract][Full Text] [Related]
6. Comparative biological activities of potent active-site analogues of alpha-melanotropin. Effect of tyrosine substitution at position-4. Wilkes BC; Sawyer TK; Hruby VJ; Hadley ME Int J Pept Protein Res; 1984 Jun; 23(6):621-9. PubMed ID: 6332085 [TBL] [Abstract][Full Text] [Related]
7. Design of potent linear alpha-melanotropin 4-10 analogues modified in positions 5 and 10. Al-Obeidi F; Hruby VJ; Castrucci AM; Hadley ME J Med Chem; 1989 Jan; 32(1):174-9. PubMed ID: 2535874 [TBL] [Abstract][Full Text] [Related]
8. Alpha-melanotropin: the minimal active sequence in the lizard skin bioassay. Castrucci AM; Hadley ME; Sawyer TK; Wilkes BC; al-Obeidi F; Staples DJ; de Vaux AE; Dym O; Hintz MF; Riehm JP Gen Comp Endocrinol; 1989 Jan; 73(1):157-63. PubMed ID: 2537778 [TBL] [Abstract][Full Text] [Related]
9. Synthesis and actions of a melanotropin conjugate, Ac-[Nle4, Glu(gamma-4'-hydroxyanilide)5, D-Phe7]alpha-MSH4-10-NH2, on melanocytes and melanoma cells in vitro. al-Obeidi F; Mulcahy M; Pitt VS; Begay V; Hadley ME; Hruby VJ J Pharm Sci; 1990 Jun; 79(6):500-4. PubMed ID: 2168479 [TBL] [Abstract][Full Text] [Related]
10. Cyclic melanotropins. 9. 7-D-Phenylalanine analogues of the active-site sequence. Cody WL; Mahoney M; Knittel JJ; Hruby VJ; Castrucci AM; Hadley ME J Med Chem; 1985 May; 28(5):583-8. PubMed ID: 2985783 [TBL] [Abstract][Full Text] [Related]
11. Synthesis of tritium labeled Ac-[Nle4, D-Phe7]-alpha-MSH4-11-NH2: a superpotent melanotropin with prolonged biological activity. Wilkes BC; Hruby VJ; Yamamura HI; Akiyama K; Castrucci AM; Hadley ME; Andrews JR; Wan YP Life Sci; 1984 Mar; 34(10):977-84. PubMed ID: 6608041 [TBL] [Abstract][Full Text] [Related]
12. Linear and cyclic alpha-melanotropin [4-10]-fragment analogues that exhibit superpotency and residual activity. Hadley ME; Marwan MM; al-Obeidi F; Hruby VJ; Castrucci AM Pigment Cell Res; 1989; 2(6):478-84. PubMed ID: 2557603 [TBL] [Abstract][Full Text] [Related]
13. Relative stability of alpha-melanotropin and related analogues to rat brain homogenates. Akiyama K; Yamamura HI; Wilkes BC; Cody WL; Hruby VJ; Castrucci AM; Hadley ME Peptides; 1984; 5(6):1191-5. PubMed ID: 6531272 [TBL] [Abstract][Full Text] [Related]
14. Prolonged stimulation of S91 melanoma tyrosinase by [Nle4, D-Phe7]-substituted alpha-melanotropins. Abdel Malek ZA; Kreutzfeld KL; Marwan MM; Hadley ME; Hruby VJ; Wilkes BC Cancer Res; 1985 Oct; 45(10):4735-40. PubMed ID: 2992767 [TBL] [Abstract][Full Text] [Related]
15. Cyclic melanotropins. 5. Importance of the C-terminal tripeptide (Lys-Pro-Val). Cody WL; Wilkes BC; Muska BJ; Hruby VJ; Castrucci AM; Hadley ME J Med Chem; 1984 Sep; 27(9):1186-90. PubMed ID: 6332195 [TBL] [Abstract][Full Text] [Related]
16. Comparative biological activities of potent analogues of alpha-melanotropin. Effect of nonaromatic and para substituted aromatic amino acids at position 7. Wilkes BC; Cody WL; Hruby VJ; Castrucci AM; Hadley ME Int J Pept Protein Res; 1986 Jun; 27(6):685-94. PubMed ID: 3489682 [TBL] [Abstract][Full Text] [Related]