140 related articles for article (PubMed ID: 2852955)
1. Cyclic lactam analogues of Ac-[Nle4]alpha-MSH4-11-NH2.
Sugg EE; Castrucci AM; Hadley ME; van Binst G; Hruby VJ
Biochemistry; 1988 Oct; 27(21):8181-8. PubMed ID: 2852955
[TBL] [Abstract][Full Text] [Related]
2. Potent and prolonged acting cyclic lactam analogues of alpha-melanotropin: design based on molecular dynamics.
Al-Obeidi F; Castrucci AM; Hadley ME; Hruby VJ
J Med Chem; 1989 Dec; 32(12):2555-61. PubMed ID: 2555512
[TBL] [Abstract][Full Text] [Related]
3. Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors.
Hruby VJ; Lu D; Sharma SD; Castrucci AL; Kesterson RA; al-Obeidi FA; Hadley ME; Cone RD
J Med Chem; 1995 Sep; 38(18):3454-61. PubMed ID: 7658432
[TBL] [Abstract][Full Text] [Related]
4. Potent and prolonged melanotropic activities of the alpha-MSH fragment analog, Ac-[Nle4,D-Phe7]-alpha-MSH4-9-NH2.
Klemes DG; Kreutzfeld KL; Hadley ME; Cody WL; Hruby VJ
Biochem Biophys Res Commun; 1986 Jun; 137(2):722-8. PubMed ID: 3089218
[TBL] [Abstract][Full Text] [Related]
5. alpha-Melanotropin: the minimal active sequence in the frog skin bioassay.
Hruby VJ; Wilkes BC; Hadley ME; Al-Obeidi F; Sawyer TK; Staples DJ; de Vaux AE; Dym O; Castrucci AM; Hintz MF
J Med Chem; 1987 Nov; 30(11):2126-30. PubMed ID: 2822931
[TBL] [Abstract][Full Text] [Related]
6. Comparative biological activities of potent active-site analogues of alpha-melanotropin. Effect of tyrosine substitution at position-4.
Wilkes BC; Sawyer TK; Hruby VJ; Hadley ME
Int J Pept Protein Res; 1984 Jun; 23(6):621-9. PubMed ID: 6332085
[TBL] [Abstract][Full Text] [Related]
7. Design of potent linear alpha-melanotropin 4-10 analogues modified in positions 5 and 10.
Al-Obeidi F; Hruby VJ; Castrucci AM; Hadley ME
J Med Chem; 1989 Jan; 32(1):174-9. PubMed ID: 2535874
[TBL] [Abstract][Full Text] [Related]
8. Alpha-melanotropin: the minimal active sequence in the lizard skin bioassay.
Castrucci AM; Hadley ME; Sawyer TK; Wilkes BC; al-Obeidi F; Staples DJ; de Vaux AE; Dym O; Hintz MF; Riehm JP
Gen Comp Endocrinol; 1989 Jan; 73(1):157-63. PubMed ID: 2537778
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and actions of a melanotropin conjugate, Ac-[Nle4, Glu(gamma-4'-hydroxyanilide)5, D-Phe7]alpha-MSH4-10-NH2, on melanocytes and melanoma cells in vitro.
al-Obeidi F; Mulcahy M; Pitt VS; Begay V; Hadley ME; Hruby VJ
J Pharm Sci; 1990 Jun; 79(6):500-4. PubMed ID: 2168479
[TBL] [Abstract][Full Text] [Related]
10. Cyclic melanotropins. 9. 7-D-Phenylalanine analogues of the active-site sequence.
Cody WL; Mahoney M; Knittel JJ; Hruby VJ; Castrucci AM; Hadley ME
J Med Chem; 1985 May; 28(5):583-8. PubMed ID: 2985783
[TBL] [Abstract][Full Text] [Related]
11. Synthesis of tritium labeled Ac-[Nle4, D-Phe7]-alpha-MSH4-11-NH2: a superpotent melanotropin with prolonged biological activity.
Wilkes BC; Hruby VJ; Yamamura HI; Akiyama K; Castrucci AM; Hadley ME; Andrews JR; Wan YP
Life Sci; 1984 Mar; 34(10):977-84. PubMed ID: 6608041
[TBL] [Abstract][Full Text] [Related]
12. Linear and cyclic alpha-melanotropin [4-10]-fragment analogues that exhibit superpotency and residual activity.
Hadley ME; Marwan MM; al-Obeidi F; Hruby VJ; Castrucci AM
Pigment Cell Res; 1989; 2(6):478-84. PubMed ID: 2557603
[TBL] [Abstract][Full Text] [Related]
13. Relative stability of alpha-melanotropin and related analogues to rat brain homogenates.
Akiyama K; Yamamura HI; Wilkes BC; Cody WL; Hruby VJ; Castrucci AM; Hadley ME
Peptides; 1984; 5(6):1191-5. PubMed ID: 6531272
[TBL] [Abstract][Full Text] [Related]
14. Prolonged stimulation of S91 melanoma tyrosinase by [Nle4, D-Phe7]-substituted alpha-melanotropins.
Abdel Malek ZA; Kreutzfeld KL; Marwan MM; Hadley ME; Hruby VJ; Wilkes BC
Cancer Res; 1985 Oct; 45(10):4735-40. PubMed ID: 2992767
[TBL] [Abstract][Full Text] [Related]
15. Cyclic melanotropins. 5. Importance of the C-terminal tripeptide (Lys-Pro-Val).
Cody WL; Wilkes BC; Muska BJ; Hruby VJ; Castrucci AM; Hadley ME
J Med Chem; 1984 Sep; 27(9):1186-90. PubMed ID: 6332195
[TBL] [Abstract][Full Text] [Related]
16. Comparative biological activities of potent analogues of alpha-melanotropin. Effect of nonaromatic and para substituted aromatic amino acids at position 7.
Wilkes BC; Cody WL; Hruby VJ; Castrucci AM; Hadley ME
Int J Pept Protein Res; 1986 Jun; 27(6):685-94. PubMed ID: 3489682
[TBL] [Abstract][Full Text] [Related]
17. Stimulation of S91 melanoma tyrosinase activity by superpotent alpha-melanotropins.
Marwan MM; Abdel Malek ZA; Kreutzfeld KL; Hadley ME; Wilkes BC; Hruby VJ; Castrucci AM
Mol Cell Endocrinol; 1985 Jul; 41(2-3):171-7. PubMed ID: 3926559
[TBL] [Abstract][Full Text] [Related]
18. Melanotropin structure-activity studies on melanocytes of the teleost fish, Synbranchus marmoratus.
Castrucci AM; Hadley ME; Wilkes BC; Hruby VJ; Sawyer TK
Gen Comp Endocrinol; 1989 May; 74(2):209-14. PubMed ID: 2714625
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis, biology, and conformations of bicyclic alpha-melanotropin analogues.
Haskell-Luevano C; Shenderovich MD; Sharma SD; Nikiforovich GV; Hadley ME; Hruby VJ
J Med Chem; 1995 May; 38(10):1736-50. PubMed ID: 7752197
[TBL] [Abstract][Full Text] [Related]
20. Biological and conformational examination of stereochemical modifications using the template melanotropin peptide, Ac-Nle-c[Asp-His-Phe-Arg-Trp-Ala-Lys]-NH2, on human melanocortin receptors.
Haskell-Luevano C; Nikiforovich G; Sharma SD; Yang YK; Dickinson C; Hruby VJ; Gantz I
J Med Chem; 1997 May; 40(11):1738-48. PubMed ID: 9171884
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
