461 related articles for article (PubMed ID: 28531315)
1. The interaction between cytosine methylation and processes of DNA replication and repair shape the mutational landscape of cancer genomes.
Poulos RC; Olivier J; Wong JWH
Nucleic Acids Res; 2017 Jul; 45(13):7786-7795. PubMed ID: 28531315
[TBL] [Abstract][Full Text] [Related]
2. Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer.
Fang H; Barbour JA; Poulos RC; Katainen R; Aaltonen LA; Wong JWH
PLoS Genet; 2020 Feb; 16(2):e1008572. PubMed ID: 32012149
[TBL] [Abstract][Full Text] [Related]
3. DNA Replication and associated repair pathways are involved in the mutagenesis of methylated cytosine.
Tomkova M; McClellan M; Kriaucionis S; Schuster-Böckler B
DNA Repair (Amst); 2018 Feb; 62():1-7. PubMed ID: 29223032
[TBL] [Abstract][Full Text] [Related]
4. DNA Polymerase ɛ Deficiency Leading to an Ultramutator Phenotype: A Novel Clinically Relevant Entity.
Castellucci E; He T; Goldstein DY; Halmos B; Chuy J
Oncologist; 2017 May; 22(5):497-502. PubMed ID: 28465371
[TBL] [Abstract][Full Text] [Related]
5. Human Pol ε-dependent replication errors and the influence of mismatch repair on their correction.
Agbor AA; Göksenin AY; LeCompte KG; Hans SH; Pursell ZF
DNA Repair (Amst); 2013 Nov; 12(11):954-63. PubMed ID: 24051051
[TBL] [Abstract][Full Text] [Related]
6. Polymerase epsilon mutations and concomitant β2-microglobulin mutations in cancer.
Voutsadakis IA
Gene; 2018 Mar; 647():31-38. PubMed ID: 29320758
[TBL] [Abstract][Full Text] [Related]
7. Clinical and epigenetic features of colorectal cancer patients with somatic POLE proofreading mutations.
Kawai T; Nyuya A; Mori Y; Tanaka T; Tanioka H; Yasui K; Toshima T; Taniguchi F; Shigeyasu K; Umeda Y; Fujiwara T; Okawaki M; Yamaguchi Y; Goel A; Nagasaka T
Clin Epigenetics; 2021 May; 13(1):117. PubMed ID: 34034807
[TBL] [Abstract][Full Text] [Related]
8. Concurrent genetic alterations in DNA polymerase proofreading and mismatch repair in human colorectal cancer.
Yoshida R; Miyashita K; Inoue M; Shimamoto A; Yan Z; Egashira A; Oki E; Kakeji Y; Oda S; Maehara Y
Eur J Hum Genet; 2011 Mar; 19(3):320-5. PubMed ID: 21157497
[TBL] [Abstract][Full Text] [Related]
9. Hypermutated tumours in the era of immunotherapy: The paradigm of personalised medicine.
Nebot-Bral L; Brandao D; Verlingue L; Rouleau E; Caron O; Despras E; El-Dakdouki Y; Champiat S; Aoufouchi S; Leary A; Marabelle A; Malka D; Chaput N; Kannouche PL
Eur J Cancer; 2017 Oct; 84():290-303. PubMed ID: 28846956
[TBL] [Abstract][Full Text] [Related]
10. Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication.
Shinbrot E; Henninger EE; Weinhold N; Covington KR; Göksenin AY; Schultz N; Chao H; Doddapaneni H; Muzny DM; Gibbs RA; Sander C; Pursell ZF; Wheeler DA
Genome Res; 2014 Nov; 24(11):1740-50. PubMed ID: 25228659
[TBL] [Abstract][Full Text] [Related]
11. Development of an MSI-positive colon tumor with aberrant DNA methylation in a PPAP patient.
Yamaguchi K; Shimizu E; Yamaguchi R; Imoto S; Komura M; Hatakeyama S; Noguchi R; Takane K; Ikenoue T; Gohda Y; Yano H; Miyano S; Furukawa Y
J Hum Genet; 2019 Aug; 64(8):729-740. PubMed ID: 31089268
[TBL] [Abstract][Full Text] [Related]
12. Mutational signatures of DNA mismatch repair deficiency in
Meier B; Volkova NV; Hong Y; Schofield P; Campbell PJ; Gerstung M; Gartner A
Genome Res; 2018 May; 28(5):666-675. PubMed ID: 29636374
[TBL] [Abstract][Full Text] [Related]
13. Clinical and molecular characterisation of hereditary and sporadic metastatic colorectal cancers harbouring microsatellite instability/DNA mismatch repair deficiency.
Cohen R; Buhard O; Cervera P; Hain E; Dumont S; Bardier A; Bachet JB; Gornet JM; Lopez-Trabada D; Dumont S; Kaci R; Bertheau P; Renaud F; Bibeau F; Parc Y; Vernerey D; Duval A; Svrcek M; André T
Eur J Cancer; 2017 Nov; 86():266-274. PubMed ID: 29055842
[TBL] [Abstract][Full Text] [Related]
14. POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status.
Hodel KP; Sun MJS; Ungerleider N; Park VS; Williams LG; Bauer DL; Immethun VE; Wang J; Suo Z; Lu H; McLachlan JB; Pursell ZF
Mol Cell; 2020 Jun; 78(6):1166-1177.e6. PubMed ID: 32497495
[TBL] [Abstract][Full Text] [Related]
15. p53 mutation is common in microsatellite stable, BRAF mutant colorectal cancers.
Bond CE; Umapathy A; Ramsnes I; Greco SA; Zhen Zhao Z; Mallitt KA; Buttenshaw RL; Montgomery GW; Leggett BA; Whitehall VL
Int J Cancer; 2012 Apr; 130(7):1567-76. PubMed ID: 21557216
[TBL] [Abstract][Full Text] [Related]
16. Down-regulation of p21 (CDKN1A/CIP1) is inversely associated with microsatellite instability and CpG island methylator phenotype (CIMP) in colorectal cancer.
Ogino S; Kawasaki T; Kirkner GJ; Ogawa A; Dorfman I; Loda M; Fuchs CS
J Pathol; 2006 Oct; 210(2):147-54. PubMed ID: 16850502
[TBL] [Abstract][Full Text] [Related]
17. Functional Analysis of Cancer-Associated DNA Polymerase ε Variants in
Barbari SR; Kane DP; Moore EA; Shcherbakova PV
G3 (Bethesda); 2018 Mar; 8(3):1019-1029. PubMed ID: 29352080
[TBL] [Abstract][Full Text] [Related]
18. Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response.
Temko D; Van Gool IC; Rayner E; Glaire M; Makino S; Brown M; Chegwidden L; Palles C; Depreeuw J; Beggs A; Stathopoulou C; Mason J; Baker AM; Williams M; Cerundolo V; Rei M; Taylor JC; Schuh A; Ahmed A; Amant F; Lambrechts D; Smit VT; Bosse T; Graham TA; Church DN; Tomlinson I
J Pathol; 2018 Jul; 245(3):283-296. PubMed ID: 29604063
[TBL] [Abstract][Full Text] [Related]
19. [Clinical and molecular consequences of microsatellite instability in human cancers].
Hamelin R; Chalastanis A; Colas C; El Bchiri J; Mercier D; Schreurs AS; Simon V; Svrcek M; Zaanan A; Borie C; Buhard O; Capel E; Zouali H; Praz F; Muleris M; Fléjou JF; Duval A
Bull Cancer; 2008 Jan; 95(1):121-32. PubMed ID: 18230578
[TBL] [Abstract][Full Text] [Related]
20. Distinctive patterns of p53 protein expression and microsatellite instability in human colorectal cancer.
Nyiraneza C; Jouret-Mourin A; Kartheuser A; Camby P; Plomteux O; Detry R; Dahan K; Sempoux C
Hum Pathol; 2011 Dec; 42(12):1897-910. PubMed ID: 21665242
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]