BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 28532668)

  • 1. Design, synthesis and biological evaluation of 4-piperazinyl-containing Chidamide derivatives as HDACs inhibitors.
    Zhang Q; Lu B; Li J
    Bioorg Med Chem Lett; 2017 Jul; 27(14):3162-3166. PubMed ID: 28532668
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis and bioevalution of novel benzamides derivatives as HDAC inhibitors.
    Li Y; Zhou Y; Qian P; Wang Y; Jiang F; Yao Z; Hu W; Zhao Y; Li S
    Bioorg Med Chem Lett; 2013 Jan; 23(1):179-82. PubMed ID: 23206867
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis and biological evaluation of novel histone deacetylase inhibitors incorporating 4-aminoquinazolinyl systems as capping groups.
    Zhang Q; Li Y; Zhang B; Lu B; Li J
    Bioorg Med Chem Lett; 2017 Nov; 27(21):4885-4888. PubMed ID: 28947154
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis and antiproliferative activities of novel benzamides derivatives as HDAC inhibitors.
    Li Y; Wang Y; Xie N; Xu M; Qian P; Zhao Y; Li S
    Eur J Med Chem; 2015 Jul; 100():270-6. PubMed ID: 26140961
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Purine/purine isoster based scaffolds as new derivatives of benzamide class of HDAC inhibitors.
    Nepali K; Chang TY; Lai MJ; Hsu KC; Yen Y; Lin TE; Lee SB; Liou JP
    Eur J Med Chem; 2020 Jun; 196():112291. PubMed ID: 32325365
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and biological evaluation of indeno[1,2-d]thiazole derivatives as potent histone deacetylase inhibitors.
    Zhou M; Ning C; Liu R; He Y; Yu N
    Bioorg Med Chem Lett; 2013 Jun; 23(11):3200-3. PubMed ID: 23639537
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and biological evaluation of novel isoindolinone derivatives as potent histone deacetylase inhibitors.
    Chen X; Zhao S; Li H; Wang X; Geng A; Cui H; Lu T; Chen Y; Zhu Y
    Eur J Med Chem; 2019 Apr; 168():110-122. PubMed ID: 30802729
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Anti-tumor activity of new orally bioavailable 2-amino-5-(thiophen-2-yl)benzamide-series histone deacetylase inhibitors, possessing an aqueous soluble functional group as a surface recognition domain.
    Hirata Y; Hirata M; Kawaratani Y; Shibano M; Taniguchi M; Yasuda M; Ohmomo Y; Nagaoka Y; Baba K; Uesato S
    Bioorg Med Chem Lett; 2012 Mar; 22(5):1926-30. PubMed ID: 22321215
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and preliminary activity assay of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as novel Histone deacetylases (HDACs) inhibitors.
    Zhang Y; Feng J; Liu C; Zhang L; Jiao J; Fang H; Su L; Zhang X; Zhang J; Li M; Wang B; Xu W
    Bioorg Med Chem; 2010 Mar; 18(5):1761-72. PubMed ID: 20171895
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of a series of substituted 2-piperazinyl-5-pyrimidylhydroxamic acids as potent histone deacetylase inhibitors.
    Angibaud P; Van Emelen K; Decrane L; van Brandt S; Ten Holte P; Pilatte I; Roux B; Poncelet V; Speybrouck D; Queguiner L; Gaurrand S; Mariën A; Floren W; Janssen L; Verdonck M; van Dun J; van Gompel J; Gilissen R; Mackie C; Du Jardin M; Peeters J; Noppe M; Van Hijfte L; Freyne E; Page M; Janicot M; Arts J
    Bioorg Med Chem Lett; 2010 Jan; 20(1):294-8. PubMed ID: 19906529
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and biological evaluation of novel coumarin-based benzamides as potent histone deacetylase inhibitors and anticancer agents.
    Abdizadeh T; Kalani MR; Abnous K; Tayarani-Najaran Z; Khashyarmanesh BZ; Abdizadeh R; Ghodsi R; Hadizadeh F
    Eur J Med Chem; 2017 May; 132():42-62. PubMed ID: 28340413
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chidamide, a histone deacetylase inhibitor, functions as a tumor inhibitor by modulating the ratio of Bax/Bcl-2 and P21 in pancreatic cancer.
    Zhao B; He T
    Oncol Rep; 2015 Jan; 33(1):304-10. PubMed ID: 25384499
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Thioether-based 2-aminobenzamide derivatives: Novel HDAC inhibitors with potent in vitro and in vivo antitumor activity.
    Yun F; Cheng C; Ullah S; He J; Zahi MR; Yuan Q
    Eur J Med Chem; 2019 Aug; 176():195-207. PubMed ID: 31103900
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis and preliminary biological evaluation of indoline-2,3-dione derivatives as novel HDAC inhibitors.
    Jin K; Li S; Li X; Zhang J; Xu W; Li X
    Bioorg Med Chem; 2015 Aug; 23(15):4728-4736. PubMed ID: 26100440
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of potent, isoform-selective inhibitors of histone deacetylase containing chiral heterocyclic capping groups and a N-(2-aminophenyl)benzamide binding unit.
    Marson CM; Matthews CJ; Yiannaki E; Atkinson SJ; Soden PE; Shukla L; Lamadema N; Thomas NS
    J Med Chem; 2013 Aug; 56(15):6156-74. PubMed ID: 23829483
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and docking studies on benzamide derivatives as histone deacetylase inhibitors.
    Lu A; Luo H; Shi M; Wu G; Yuan Y; Liu J; Tang F
    Bioorg Med Chem Lett; 2011 Aug; 21(16):4924-7. PubMed ID: 21741834
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of adamantane based highly potent HDAC inhibitors.
    Gopalan B; Ponpandian T; Kachhadia V; Bharathimohan K; Vignesh R; Sivasudar V; Narayanan S; Mandar B; Praveen R; Saranya N; Rajagopal S; Rajagopal S
    Bioorg Med Chem Lett; 2013 May; 23(9):2532-7. PubMed ID: 23538115
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel histone deacetylase inhibitor Chidamide induces apoptosis of human colon cancer cells.
    Liu L; Chen B; Qin S; Li S; He X; Qiu S; Zhao W; Zhao H
    Biochem Biophys Res Commun; 2010 Feb; 392(2):190-5. PubMed ID: 20060381
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure and property based design, synthesis and biological evaluation of γ-lactam based HDAC inhibitors.
    Choi E; Lee C; Park JE; Seo JJ; Cho M; Kang JS; Kim HM; Park SK; Lee K; Han G
    Bioorg Med Chem Lett; 2011 Feb; 21(4):1218-21. PubMed ID: 21256006
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Application of p21 and klf2 reporter gene assays to identify selective histone deacetylase inhibitors for cancer therapy.
    Wong JC; Guo L; Peng Z; Zhang W; Zhang N; Lai W; Zhang Z; Zhang C; Zhang X; Song S; Pan D; Xie C; Li J; Ning Z; Lu X; He Y; Chen L
    Bioorg Med Chem Lett; 2011 Jan; 21(1):110-6. PubMed ID: 21145737
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.