BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 28534261)

  • 21. Application of a cocktail approach to screen cytochrome P450 BM3 libraries for metabolic activity and diversity.
    Reinen J; Postma G; Tump C; Bloemberg T; Engel J; Vermeulen NP; Commandeur JN; Honing M
    Anal Bioanal Chem; 2016 Feb; 408(5):1425-43. PubMed ID: 26753974
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Enzyme kinetics for clinically relevant CYP inhibition.
    Zhang ZY; Wong YN
    Curr Drug Metab; 2005 Jun; 6(3):241-57. PubMed ID: 15975042
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Evaluation of the in vitro and in vivo metabolic pathway and cytochrome P450 inhibition/induction profile of Huperzine A.
    Lin PP; Li XN; Yuan F; Chen WL; Yang MJ; Xu HR
    Biochem Biophys Res Commun; 2016 Nov; 480(2):248-253. PubMed ID: 27751854
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Are circulating metabolites important in drug-drug interactions?: Quantitative analysis of risk prediction and inhibitory potency.
    Yeung CK; Fujioka Y; Hachad H; Levy RH; Isoherranen N
    Clin Pharmacol Ther; 2011 Jan; 89(1):105-13. PubMed ID: 21124313
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Differences in Toxicological and Pharmacological Responses Mediated by Polymorphic Cytochromes P450 and Related Drug-Metabolizing Enzymes.
    Yamazaki H
    Chem Res Toxicol; 2017 Jan; 30(1):53-60. PubMed ID: 27750412
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Introduction to in vitro estimation of metabolic stability and drug interactions of new chemical entities in drug discovery and development.
    Baranczewski P; Stańczak A; Sundberg K; Svensson R; Wallin A; Jansson J; Garberg P; Postlind H
    Pharmacol Rep; 2006; 58(4):453-72. PubMed ID: 16963792
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Rule-Based Prediction Models of Cytochrome P450 Inhibition.
    Su BH; Tu YS; Lin C; Shao CY; Lin OA; Tseng YJ
    J Chem Inf Model; 2015 Jul; 55(7):1426-34. PubMed ID: 26108525
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Development and validation of a liquid-chromatography high-resolution tandem mass spectrometry approach for quantification of nine cytochrome P450 (CYP) model substrate metabolites in an in vitro CYP inhibition cocktail.
    Dinger J; Meyer MR; Maurer HH
    Anal Bioanal Chem; 2014 Jul; 406(18):4453-64. PubMed ID: 24830396
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Accurate Estimation of In Vivo Inhibition Constants of Inhibitors and Fraction Metabolized of Substrates with Physiologically Based Pharmacokinetic Drug-Drug Interaction Models Incorporating Parent Drugs and Metabolites of Substrates with Cluster Newton Method.
    Yoshida K; Maeda K; Konagaya A; Kusuhara H
    Drug Metab Dispos; 2018 Nov; 46(11):1805-1816. PubMed ID: 30135241
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Prevalence and sort of pharmacokinetic drug-drug interactions in hospitalized psychiatric patients.
    Hefner G; Wolff J; Hahn M; Hiemke C; Toto S; Roll SC; Messer T; Klimke A
    J Neural Transm (Vienna); 2020 Aug; 127(8):1185-1198. PubMed ID: 32519194
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Simultaneous and comprehensive in vivo analysis of cytochrome P450 activity by using a cocktail approach in rats.
    Uchida S; Tanaka S; Namiki N
    Biopharm Drug Dispos; 2014 May; 35(4):228-36. PubMed ID: 24395703
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Structure-based ligand design to overcome CYP inhibition in drug discovery projects.
    Brändén G; Sjögren T; Schnecke V; Xue Y
    Drug Discov Today; 2014 Jul; 19(7):905-11. PubMed ID: 24642031
    [TBL] [Abstract][Full Text] [Related]  

  • 33. High-throughput screening for stability and inhibitory activity of compounds toward cytochrome P450-mediated metabolism.
    Ansede JH; Thakker DR
    J Pharm Sci; 2004 Feb; 93(2):239-55. PubMed ID: 14705182
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The prevalence of co-prescription of clinically relevant CYP enzyme inhibitor and substrate drugs in community-dwelling elderly Australians.
    Kerr KP; Mate KE; Magin PJ; Marley J; Stocks NP; Disler P; Pond CD
    J Clin Pharm Ther; 2014 Aug; 39(4):383-9. PubMed ID: 24702306
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mechanisms of inhibitory and regulatory effects of methylenedioxyphenyl compounds on cytochrome P450-dependent drug oxidation.
    Murray M
    Curr Drug Metab; 2000 Jul; 1(1):67-84. PubMed ID: 11467081
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Understanding the transport properties of metabolites: case studies and considerations for drug development.
    Zamek-Gliszczynski MJ; Chu X; Polli JW; Paine MF; Galetin A
    Drug Metab Dispos; 2014 Apr; 42(4):650-64. PubMed ID: 24346835
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Ximelagatran, an oral direct thrombin inhibitor, has a low potential for cytochrome P450-mediated drug-drug interactions.
    Bredberg E; Andersson TB; Frison L; Thuresson A; Johansson S; Eriksson-Lepkowska M; Larsson M; Eriksson UG
    Clin Pharmacokinet; 2003; 42(8):765-77. PubMed ID: 12846597
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Cytochrome p450 inhibitory properties of common efflux transporter inhibitors.
    Englund G; Lundquist P; Skogastierna C; Johansson J; Hoogstraate J; Afzelius L; Andersson TB; Projean D
    Drug Metab Dispos; 2014 Mar; 42(3):441-7. PubMed ID: 24396142
    [TBL] [Abstract][Full Text] [Related]  

  • 39. In vitro and in silico Approaches to Study Cytochrome P450-Mediated Interactions.
    Tan BH; Pan Y; Dong AN; Ong CE
    J Pharm Pharm Sci; 2017; 20(1):319-328. PubMed ID: 29145931
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Metabolic interactions of magnolol with cytochrome P450 enzymes: uncompetitive inhibition of CYP1A and competitive inhibition of CYP2C.
    Kim SB; Kang HE; Cho HJ; Kim YS; Chung SJ; Yoon IS; Kim DD
    Drug Dev Ind Pharm; 2016; 42(2):263-9. PubMed ID: 26133083
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.