These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
174 related articles for article (PubMed ID: 28535453)
1. Inhibition of Neddylation Modification Sensitizes Pancreatic Cancer Cells to Gemcitabine. Li H; Zhou W; Li L; Wu J; Liu X; Zhao L; Jia L; Sun Y Neoplasia; 2017 Jun; 19(6):509-518. PubMed ID: 28535453 [TBL] [Abstract][Full Text] [Related]
2. Inhibition of neddylation modification by MLN4924 sensitizes hepatocellular carcinoma cells to sorafenib. Yang Z; Zhang J; Lin X; Wu D; Li G; Zhong C; Fang L; Jiang P; Yin L; Zhang L; Bie P; Xie CM Oncol Rep; 2019 Jun; 41(6):3257-3269. PubMed ID: 31002342 [TBL] [Abstract][Full Text] [Related]
3. Targeting protein neddylation with an NEDD8-activating enzyme inhibitor MLN4924 induced apoptosis or senescence in human lymphoma cells. Wang Y; Luo Z; Pan Y; Wang W; Zhou X; Jeong LS; Chu Y; Liu J; Jia L Cancer Biol Ther; 2015; 16(3):420-9. PubMed ID: 25782162 [TBL] [Abstract][Full Text] [Related]
4. Suppression of tumor angiogenesis by targeting the protein neddylation pathway. Yao WT; Wu JF; Yu GY; Wang R; Wang K; Li LH; Chen P; Jiang YN; Cheng H; Lee HW; Yu J; Qi H; Yu XJ; Wang P; Chu YW; Yang M; Hua ZC; Ying HQ; Hoffman RM; Jeong LS; Jia LJ Cell Death Dis; 2014 Feb; 5(2):e1059. PubMed ID: 24525735 [TBL] [Abstract][Full Text] [Related]
5. Overactivated neddylation pathway as a therapeutic target in lung cancer. Li L; Wang M; Yu G; Chen P; Li H; Wei D; Zhu J; Xie L; Jia H; Shi J; Li C; Yao W; Wang Y; Gao Q; Jeong LS; Lee HW; Yu J; Hu F; Mei J; Wang P; Chu Y; Qi H; Yang M; Dong Z; Sun Y; Hoffman RM; Jia L J Natl Cancer Inst; 2014 Jun; 106(6):dju083. PubMed ID: 24853380 [TBL] [Abstract][Full Text] [Related]
6. MLN4924, a novel protein neddylation inhibitor, suppresses proliferation and migration of human urothelial carcinoma: In vitro and in vivo studies. Kuo KL; Ho IL; Shi CS; Wu JT; Lin WC; Tsai YC; Chang HC; Chou CT; Hsu CH; Hsieh JT; Chang SC; Pu YS; Huang KH Cancer Lett; 2015 Jul; 363(2):127-36. PubMed ID: 25615422 [TBL] [Abstract][Full Text] [Related]
7. Validation of NEDD8-conjugating enzyme UBC12 as a new therapeutic target in lung cancer. Li L; Kang J; Zhang W; Cai L; Wang S; Liang Y; Jiang Y; Liu X; Zhang Y; Ruan H; Chen G; Wang M; Jia L EBioMedicine; 2019 Jul; 45():81-91. PubMed ID: 31208947 [TBL] [Abstract][Full Text] [Related]
8. Neddylation Inactivation Facilitates FOXO3a Nuclear Export to Suppress Estrogen Receptor Transcription and Improve Fulvestrant Sensitivity. Jia X; Li C; Li L; Liu X; Zhou L; Zhang W; Ni S; Lu Y; Chen L; Jeong LS; Yu J; Zhang Y; Zhang J; He S; Hu X; Sun H; Yu K; Liu G; Zhao H; Zhang Y; Jia L; Shao ZM Clin Cancer Res; 2019 Jun; 25(12):3658-3672. PubMed ID: 30833270 [TBL] [Abstract][Full Text] [Related]
9. A first-in-class inhibitor, MLN4924 (pevonedistat), induces cell-cycle arrest, senescence, and apoptosis in human renal cell carcinoma by suppressing UBE2M-dependent neddylation modification. Xu B; Deng Y; Bi R; Guo H; Shu C; Shah NK; Chang J; Liu G; Du Y; Wei W; Wang C Cancer Chemother Pharmacol; 2018 Jun; 81(6):1083-1093. PubMed ID: 29667067 [TBL] [Abstract][Full Text] [Related]
10. Neddylation Blockade Diminishes Hepatic Metastasis by Dampening Cancer Stem-Like Cells and Angiogenesis in Uveal Melanoma. Jin Y; Zhang P; Wang Y; Jin B; Zhou J; Zhang J; Pan J Clin Cancer Res; 2018 Aug; 24(15):3741-3754. PubMed ID: 29233905 [No Abstract] [Full Text] [Related]
11. LAMC2 promotes cancer progression and gemcitabine resistance through modulation of EMT and ATP-binding cassette transporters in pancreatic ductal adenocarcinoma. Okada Y; Takahashi N; Takayama T; Goel A Carcinogenesis; 2021 Apr; 42(4):546-556. PubMed ID: 33624791 [TBL] [Abstract][Full Text] [Related]
12. Radiosensitization of human pancreatic cancer cells by MLN4924, an investigational NEDD8-activating enzyme inhibitor. Wei D; Li H; Yu J; Sebolt JT; Zhao L; Lawrence TS; Smith PG; Morgan MA; Sun Y Cancer Res; 2012 Jan; 72(1):282-93. PubMed ID: 22072567 [TBL] [Abstract][Full Text] [Related]
13. MLN4924 (Pevonedistat), a protein neddylation inhibitor, suppresses proliferation and migration of human clear cell renal cell carcinoma. Tong S; Si Y; Yu H; Zhang L; Xie P; Jiang W Sci Rep; 2017 Jul; 7(1):5599. PubMed ID: 28717191 [TBL] [Abstract][Full Text] [Related]
14. Regulation of pH by Carbonic Anhydrase 9 Mediates Survival of Pancreatic Cancer Cells With Activated KRAS in Response to Hypoxia. McDonald PC; Chafe SC; Brown WS; Saberi S; Swayampakula M; Venkateswaran G; Nemirovsky O; Gillespie JA; Karasinska JM; Kalloger SE; Supuran CT; Schaeffer DF; Bashashati A; Shah SP; Topham JT; Yapp DT; Li J; Renouf DJ; Stanger BZ; Dedhar S Gastroenterology; 2019 Sep; 157(3):823-837. PubMed ID: 31078621 [TBL] [Abstract][Full Text] [Related]
16. Inhibition of neddylation facilitates cell migration through enhanced phosphorylation of caveolin-1 in PC3 and U373MG cells. Park SY; Park JW; Lee GW; Li L; Chun YS BMC Cancer; 2018 Jan; 18(1):30. PubMed ID: 29301501 [TBL] [Abstract][Full Text] [Related]
17. MLN4924 suppresses neddylation and induces cell cycle arrest, senescence, and apoptosis in human osteosarcoma. Zhang Y; Shi CC; Zhang HP; Li GQ; Li SS Oncotarget; 2016 Jul; 7(29):45263-45274. PubMed ID: 27223074 [TBL] [Abstract][Full Text] [Related]
18. MLN4924 inhibits cell proliferation by targeting the activated neddylation pathway in endometrial carcinoma. Liu H; Bei Q; Luo X J Int Med Res; 2021 Jun; 49(6):3000605211018592. PubMed ID: 34082605 [TBL] [Abstract][Full Text] [Related]
19. Neddylation pathway is up-regulated in human intrahepatic cholangiocarcinoma and serves as a potential therapeutic target. Gao Q; Yu GY; Shi JY; Li LH; Zhang WJ; Wang ZC; Yang LX; Duan M; Zhao H; Wang XY; Zhou J; Qiu SJ; Jeong LS; Jia LJ; Fan J Oncotarget; 2014 Sep; 5(17):7820-32. PubMed ID: 25229838 [TBL] [Abstract][Full Text] [Related]
20. Extracellular lumican augments cytotoxicity of chemotherapy in pancreatic ductal adenocarcinoma cells via autophagy inhibition. Li X; Roife D; Kang Y; Dai B; Pratt M; Fleming JB Oncogene; 2016 Sep; 35(37):4881-90. PubMed ID: 26876211 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]