BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 28536275)

  • 1. SIRT3-Mediated Dimerization of IDH2 Directs Cancer Cell Metabolism and Tumor Growth.
    Zou X; Zhu Y; Park SH; Liu G; O'Brien J; Jiang H; Gius D
    Cancer Res; 2017 Aug; 77(15):3990-3999. PubMed ID: 28536275
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SIRT3 and GCN5L regulation of NADP+- and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2.
    Smolková K; Špačková J; Gotvaldová K; Dvořák A; Křenková A; Hubálek M; Holendová B; Vítek L; Ježek P
    Sci Rep; 2020 May; 10(1):8677. PubMed ID: 32457458
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SIRT3 protein deacetylates isocitrate dehydrogenase 2 (IDH2) and regulates mitochondrial redox status.
    Yu W; Dittenhafer-Reed KE; Denu JM
    J Biol Chem; 2012 Apr; 287(17):14078-86. PubMed ID: 22416140
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hypertrophic preconditioning attenuates post-myocardial infarction injury through deacetylation of isocitrate dehydrogenase 2.
    Ma LL; Kong FJ; Ma YJ; Guo JJ; Wang SJ; Dong Z; Sun AJ; Zou YZ; Ge JB
    Acta Pharmacol Sin; 2021 Dec; 42(12):2004-2015. PubMed ID: 34163022
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Loss of SIRT3 Provides Growth Advantage for B Cell Malignancies.
    Yu W; Denu RA; Krautkramer KA; Grindle KM; Yang DT; Asimakopoulos F; Hematti P; Denu JM
    J Biol Chem; 2016 Feb; 291(7):3268-79. PubMed ID: 26631723
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hypertrophic preconditioning attenuates myocardial ischemia/reperfusion injury through the deacetylation of isocitrate dehydrogenase 2.
    Ma L; Shi H; Li Y; Gao W; Guo J; Zhu J; Dong Z; Sun A; Zou Y; Ge J
    Sci Bull (Beijing); 2021 Oct; 66(20):2099-2114. PubMed ID: 36654268
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Overexpression of Sirt3 inhibits lipid accumulation in macrophages through mitochondrial IDH2 deacetylation.
    Sheng S; Kang Y; Guo Y; Pu Q; Cai M; Tu Z
    Int J Clin Exp Pathol; 2015; 8(8):9196-201. PubMed ID: 26464666
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells.
    Chen D; Xia S; Zhang R; Li Y; Famulare CA; Fan H; Wu R; Wang M; Zhu AC; Elf SE; Su R; Dong L; Arellano M; Blum WG; Mao H; Lonial S; Stock W; Odenike O; Le Beau M; Boggon TJ; He C; Chen J; Gao X; Levine RL; Chen J
    Mol Cell; 2021 Sep; 81(18):3833-3847.e11. PubMed ID: 34289383
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Manganese Superoxide Dismutase Acetylation and Dysregulation, Due to Loss of SIRT3 Activity, Promote a Luminal B-Like Breast Carcinogenic-Permissive Phenotype.
    Zou X; Santa-Maria CA; O'Brien J; Gius D; Zhu Y
    Antioxid Redox Signal; 2016 Aug; 25(6):326-36. PubMed ID: 26935174
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Wild-type IDH2 contributes to Epstein-Barr virus-dependent metabolic alterations and tumorigenesis.
    Shi F; He Y; Li J; Tang M; Li Y; Xie L; Zhao L; Hu J; Luo X; Zhou M; Liu N; Fan J; Zhou J; Gao Q; Qiu S; Wu W; Zhang X; Jia W; Bode AM; Cao Y
    Mol Metab; 2020 Jun; 36():100966. PubMed ID: 32224436
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Suppression of tumorigenesis in mitochondrial NADP(+)-dependent isocitrate dehydrogenase knock-out mice.
    Kim S; Kim SY; Ku HJ; Jeon YH; Lee HW; Lee J; Kwon TK; Park KM; Park JW
    Biochim Biophys Acta; 2014 Feb; 1842(2):135-43. PubMed ID: 24240089
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SIRT3 Enhances Glycolysis and Proliferation in SIRT3-Expressing Gastric Cancer Cells.
    Cui Y; Qin L; Wu J; Qu X; Hou C; Sun W; Li S; Vaughan AT; Li JJ; Liu J
    PLoS One; 2015; 10(6):e0129834. PubMed ID: 26121691
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells.
    Ozden O; Park SH; Wagner BA; Song HY; Zhu Y; Vassilopoulos A; Jung B; Buettner GR; Gius D
    Free Radic Biol Med; 2014 Nov; 76():163-172. PubMed ID: 25152236
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SIRT3 deacetylated and increased citrate synthase activity in PD model.
    Cui XX; Li X; Dong SY; Guo YJ; Liu T; Wu YC
    Biochem Biophys Res Commun; 2017 Mar; 484(4):767-773. PubMed ID: 28161643
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Exogenous H
    Sun Y; Tian Z; Liu N; Zhang L; Gao Z; Sun X; Yu M; Wu J; Yang F; Zhao Y; Ren H; Chen H; Zhao D; Wang Y; Dong S; Xu C; Lu F; Zhang W
    J Mol Med (Berl); 2018 Apr; 96(3-4):281-299. PubMed ID: 29349500
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Wild-type IDH2 promotes the Warburg effect and tumor growth through HIF1α in lung cancer.
    Li J; He Y; Tan Z; Lu J; Li L; Song X; Shi F; Xie L; You S; Luo X; Li N; Li Y; Liu X; Tang M; Weng X; Yi W; Fan J; Zhou J; Qiang G; Qiu S; Wu W; Bode AM; Cao Y
    Theranostics; 2018; 8(15):4050-4061. PubMed ID: 30128035
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer.
    Jiang W; He T; Liu S; Zheng Y; Xiang L; Pei X; Wang Z; Yang H
    J Hematol Oncol; 2018 Dec; 11(1):139. PubMed ID: 30547809
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction.
    Someya S; Yu W; Hallows WC; Xu J; Vann JM; Leeuwenburgh C; Tanokura M; Denu JM; Prolla TA
    Cell; 2010 Nov; 143(5):802-12. PubMed ID: 21094524
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SUMOylation enhances the activity of IDH2 under oxidative stress.
    Yu Y; Chen Y; Liu K; Cheng J; Tu J
    Biochem Biophys Res Commun; 2020 Nov; 532(4):591-597. PubMed ID: 32900482
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SIRT2-Mediated Deacetylation and Tetramerization of Pyruvate Kinase Directs Glycolysis and Tumor Growth.
    Park SH; Ozden O; Liu G; Song HY; Zhu Y; Yan Y; Zou X; Kang HJ; Jiang H; Principe DR; Cha YI; Roh M; Vassilopoulos A; Gius D
    Cancer Res; 2016 Jul; 76(13):3802-12. PubMed ID: 27197174
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.