152 related articles for article (PubMed ID: 28541532)
1. Constitutive Activation of AKT2 in Humans Leads to Hypoglycemia Without Fatty Liver or Metabolic Dyslipidemia.
Minic M; Rocha N; Harris J; Groeneveld MP; Leiter S; Wareham N; Sleigh A; De Lonlay P; Hussain K; O'Rahilly S; Semple RK
J Clin Endocrinol Metab; 2017 Aug; 102(8):2914-2921. PubMed ID: 28541532
[TBL] [Abstract][Full Text] [Related]
2. An activating mutation of AKT2 and human hypoglycemia.
Hussain K; Challis B; Rocha N; Payne F; Minic M; Thompson A; Daly A; Scott C; Harris J; Smillie BJ; Savage DB; Ramaswami U; De Lonlay P; O'Rahilly S; Barroso I; Semple RK
Science; 2011 Oct; 334(6055):474. PubMed ID: 21979934
[TBL] [Abstract][Full Text] [Related]
3. Activating AKT2 mutation: hypoinsulinemic hypoketotic hypoglycemia.
Arya VB; Flanagan SE; Schober E; Rami-Merhar B; Ellard S; Hussain K
J Clin Endocrinol Metab; 2014 Feb; 99(2):391-4. PubMed ID: 24285683
[TBL] [Abstract][Full Text] [Related]
4. Recurrent hypoglycemia increases hepatic gluconeogenesis without affecting glycogen metabolism or systemic lipolysis in rat.
Liu Z; Zhang L; Qian C; Zhou Y; Yu Q; Yuan J; Lv Y; Zhang L; Chang X; Li Y; Liu Y
Metabolism; 2022 Nov; 136():155310. PubMed ID: 36063868
[TBL] [Abstract][Full Text] [Related]
5. Efficacy and safety of sirolimus therapy in familial hypoinsulinemic hypoglycemia caused by AKT2 mutation inherited from the mosaic father.
Dushar M; Nowaczyk J; Pyrżak B; Akopyan H; Śmigiel R; Walczak A; Rydzanicz M; Płoski R; Szczałuba K
Eur J Med Genet; 2021 Dec; 64(12):104368. PubMed ID: 34673243
[TBL] [Abstract][Full Text] [Related]
6. Hepatic mTOR-AKT2-Insig2 signaling pathway contributes to the improvement of hepatic steatosis after Roux-en-Y Gastric Bypass in mice.
Pan Q; Qin T; Gao Y; Li S; Li D; Peng M; Zhai H; Xu G
Biochim Biophys Acta Mol Basis Dis; 2019 Mar; 1865(3):525-534. PubMed ID: 30562559
[TBL] [Abstract][Full Text] [Related]
7. Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis.
Semple RK; Sleigh A; Murgatroyd PR; Adams CA; Bluck L; Jackson S; Vottero A; Kanabar D; Charlton-Menys V; Durrington P; Soos MA; Carpenter TA; Lomas DJ; Cochran EK; Gorden P; O'Rahilly S; Savage DB
J Clin Invest; 2009 Feb; 119(2):315-22. PubMed ID: 19164855
[TBL] [Abstract][Full Text] [Related]
8. Treatment of hypoglycemia due to a rare pathogenic variant in
Parker M; Yau D
Clin Case Rep; 2024 Feb; 12(2):e8473. PubMed ID: 38344362
[TBL] [Abstract][Full Text] [Related]
9. Akt2 is required for hepatic lipid accumulation in models of insulin resistance.
Leavens KF; Easton RM; Shulman GI; Previs SF; Birnbaum MJ
Cell Metab; 2009 Nov; 10(5):405-18. PubMed ID: 19883618
[TBL] [Abstract][Full Text] [Related]
10. Identification of Akt-independent regulation of hepatic lipogenesis by mammalian target of rapamycin (mTOR) complex 2.
Yuan M; Pino E; Wu L; Kacergis M; Soukas AA
J Biol Chem; 2012 Aug; 287(35):29579-88. PubMed ID: 22773877
[TBL] [Abstract][Full Text] [Related]
11. Acetyl-CoA carboxylase 2-/- mutant mice are protected against fatty liver under high-fat, high-carbohydrate dietary and de novo lipogenic conditions.
Abu-Elheiga L; Wu H; Gu Z; Bressler R; Wakil SJ
J Biol Chem; 2012 Apr; 287(15):12578-88. PubMed ID: 22362781
[TBL] [Abstract][Full Text] [Related]
12. Hypoinsulinaemic, hypoketotic hypoglycaemia due to mosaic genetic activation of PI3-kinase.
Leiter SM; Parker VER; Welters A; Knox R; Rocha N; Clark G; Payne F; Lotta L; Harris J; Guerrero-Fernández J; González-Casado I; García-Miñaur S; Gordo G; Wareham N; Martínez-Glez V; Allison M; O'Rahilly S; Barroso I; Meissner T; Davies S; Hussain K; Temple K; Barreda-Bonis AC; Kummer S; Semple RK
Eur J Endocrinol; 2017 Aug; 177(2):175-186. PubMed ID: 28566443
[TBL] [Abstract][Full Text] [Related]
13. Insulin-mediated FFA suppression is associated with triglyceridemia and insulin sensitivity independent of adiposity.
Bush NC; Basu R; Rizza RA; Nair KS; Khosla S; Jensen MD
J Clin Endocrinol Metab; 2012 Nov; 97(11):4130-8. PubMed ID: 22933539
[TBL] [Abstract][Full Text] [Related]
14. Chronic physiologic hyperinsulinemia impairs suppression of plasma free fatty acids and increases de novo lipogenesis but does not cause dyslipidemia in conscious normal rats.
Koopmans SJ; Kushwaha RS; DeFronzo RA
Metabolism; 1999 Mar; 48(3):330-7. PubMed ID: 10094109
[TBL] [Abstract][Full Text] [Related]
15. Investigating dual inhibition of ACC and CD36 for the treatment of nonalcoholic fatty liver disease in mice.
Devereux CJ; Bayliss J; Keenan SN; Montgomery MK; Watt MJ
Am J Physiol Endocrinol Metab; 2023 Feb; 324(2):E187-E198. PubMed ID: 36629823
[TBL] [Abstract][Full Text] [Related]
16. JTP-103237, a monoacylglycerol acyltransferase inhibitor, prevents fatty liver and suppresses both triglyceride synthesis and de novo lipogenesis.
Okuma C; Ohta T; Tadaki H; Ishigure T; Sakata S; Taniuchi H; Sano R; Hamada H; Kume S; Nishiu J; Kakutani M
J Pharmacol Sci; 2015 Jul; 128(3):150-7. PubMed ID: 26215699
[TBL] [Abstract][Full Text] [Related]
17. Impaired Very-Low-Density Lipoprotein catabolism links hypoglycemia to hypertriglyceridemia in Glycogen Storage Disease type Ia.
Hoogerland JA; Peeks F; Hijmans BS; Wolters JC; Kooijman S; Bos T; Bleeker A; van Dijk TH; Wolters H; Gerding A; van Eunen K; Havinga R; Pronk ACM; Rensen PCN; Mithieux G; Rajas F; Kuipers F; Reijngoud DJ; Derks TGJ; Oosterveer MH
J Inherit Metab Dis; 2021 Jul; 44(4):879-892. PubMed ID: 33739445
[TBL] [Abstract][Full Text] [Related]
18. Hepatic oleate regulates adipose tissue lipogenesis and fatty acid oxidation.
Burhans MS; Flowers MT; Harrington KR; Bond LM; Guo CA; Anderson RM; Ntambi JM
J Lipid Res; 2015 Feb; 56(2):304-18. PubMed ID: 25555387
[TBL] [Abstract][Full Text] [Related]
19. Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease.
Kawano Y; Cohen DE
J Gastroenterol; 2013 Apr; 48(4):434-41. PubMed ID: 23397118
[TBL] [Abstract][Full Text] [Related]
20. De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health.
Eissing L; Scherer T; Tödter K; Knippschild U; Greve JW; Buurman WA; Pinnschmidt HO; Rensen SS; Wolf AM; Bartelt A; Heeren J; Buettner C; Scheja L
Nat Commun; 2013; 4():1528. PubMed ID: 23443556
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]