466 related articles for article (PubMed ID: 28544245)
1. Ghrelin receptor inverse agonists as a novel therapeutic approach against obesity-related metabolic disease.
Abegg K; Bernasconi L; Hutter M; Whiting L; Pietra C; Giuliano C; Lutz TA; Riediger T
Diabetes Obes Metab; 2017 Dec; 19(12):1740-1750. PubMed ID: 28544245
[TBL] [Abstract][Full Text] [Related]
2. Rats with a truncated ghrelin receptor (GHSR) do not respond to ghrelin, and show reduced intake of palatable, high-calorie food.
MacKay H; Charbonneau VR; St-Onge V; Murray E; Watts A; Wellman MK; Abizaid A
Physiol Behav; 2016 Sep; 163():88-96. PubMed ID: 27129673
[TBL] [Abstract][Full Text] [Related]
3. Ipragliflozin Improves Hepatic Steatosis in Obese Mice and Liver Dysfunction in Type 2 Diabetic Patients Irrespective of Body Weight Reduction.
Komiya C; Tsuchiya K; Shiba K; Miyachi Y; Furuke S; Shimazu N; Yamaguchi S; Kanno K; Ogawa Y
PLoS One; 2016; 11(3):e0151511. PubMed ID: 26977813
[TBL] [Abstract][Full Text] [Related]
4. Synergistic metabolic benefits of an exenatide analogue and cholecystokinin in diet-induced obese and leptin-deficient rodents.
Trevaskis JL; Sun C; Athanacio J; D'Souza L; Samant M; Tatarkiewicz K; Griffin PS; Wittmer C; Wang Y; Teng CH; Forood B; Parkes DG; Roth JD
Diabetes Obes Metab; 2015 Jan; 17(1):61-73. PubMed ID: 25204356
[TBL] [Abstract][Full Text] [Related]
5. Development of Nonpeptidic Inverse Agonists of the Ghrelin Receptor (GHSR) Based on the 1,2,4-Triazole Scaffold.
Haj Salah KB; Maingot M; Blayo AL; M'Kadmi C; Damian M; Mary S; Cantel S; Neasta J; Oiry C; Péraldi-Roux S; Fernandez G; Romero GG; Perello M; Marie J; Banères JL; Fehrentz JA; Denoyelle S
J Med Chem; 2020 Oct; 63(19):10796-10815. PubMed ID: 32882134
[TBL] [Abstract][Full Text] [Related]
6. Beneficial long-term antidiabetic actions of N- and C-terminally modified analogues of apelin-13 in diet-induced obese diabetic mice.
Parthsarathy V; Hogg C; Flatt PR; O'Harte FPM
Diabetes Obes Metab; 2018 Feb; 20(2):319-327. PubMed ID: 28730728
[TBL] [Abstract][Full Text] [Related]
7. A novel and selective melanin-concentrating hormone receptor 1 antagonist ameliorates obesity and hepatic steatosis in diet-induced obese rodent models.
Kawata Y; Okuda S; Hotta N; Igawa H; Takahashi M; Ikoma M; Kasai S; Ando A; Satomi Y; Nishida M; Nakayama M; Yamamoto S; Nagisa Y; Takekawa S
Eur J Pharmacol; 2017 Feb; 796():45-53. PubMed ID: 27986627
[TBL] [Abstract][Full Text] [Related]
8. Amylin improves the effect of leptin on insulin sensitivity in leptin-resistant diet-induced obese mice.
Kusakabe T; Ebihara K; Sakai T; Miyamoto L; Aotani D; Yamamoto Y; Yamamoto-Kataoka S; Aizawa-Abe M; Fujikura J; Hosoda K; Nakao K
Am J Physiol Endocrinol Metab; 2012 Apr; 302(8):E924-31. PubMed ID: 22275759
[TBL] [Abstract][Full Text] [Related]
9. Running on mixed fuel-dual agonistic approach of GLP-1 and GCG receptors leads to beneficial impact on body weight and blood glucose control: A comparative study between mice and non-human primates.
Elvert R; Herling AW; Bossart M; Weiss T; Zhang B; Wenski P; Wandschneider J; Kleutsch S; Butty U; Kannt A; Wagner M; Haack T; Evers A; Dudda A; Lorenz M; Keil S; Larsen PJ
Diabetes Obes Metab; 2018 Aug; 20(8):1836-1851. PubMed ID: 29938884
[TBL] [Abstract][Full Text] [Related]
10. Differential gene regulation of GHSR signaling pathway in the arcuate nucleus and NPY neurons by fasting, diet-induced obesity, and 17β-estradiol.
Yasrebi A; Hsieh A; Mamounis KJ; Krumm EA; Yang JA; Magby J; Hu P; Roepke TA
Mol Cell Endocrinol; 2016 Feb; 422():42-56. PubMed ID: 26577678
[TBL] [Abstract][Full Text] [Related]
11. Neuronal Deletion of Ghrelin Receptor Almost Completely Prevents Diet-Induced Obesity.
Lee JH; Lin L; Xu P; Saito K; Wei Q; Meadows AG; Bongmba OY; Pradhan G; Zheng H; Xu Y; Sun Y
Diabetes; 2016 Aug; 65(8):2169-78. PubMed ID: 27207529
[TBL] [Abstract][Full Text] [Related]
12. N-Terminal Liver-Expressed Antimicrobial Peptide 2 (LEAP2) Region Exhibits Inverse Agonist Activity toward the Ghrelin Receptor.
M'Kadmi C; Cabral A; Barrile F; Giribaldi J; Cantel S; Damian M; Mary S; Denoyelle S; Dutertre S; Péraldi-Roux S; Neasta J; Oiry C; Banères JL; Marie J; Perello M; Fehrentz JA
J Med Chem; 2019 Jan; 62(2):965-973. PubMed ID: 30543423
[TBL] [Abstract][Full Text] [Related]
13. Diet-induced obesity causes ghrelin resistance in arcuate NPY/AgRP neurons.
Briggs DI; Enriori PJ; Lemus MB; Cowley MA; Andrews ZB
Endocrinology; 2010 Oct; 151(10):4745-55. PubMed ID: 20826561
[TBL] [Abstract][Full Text] [Related]
14. Anti-obesity effects of KR-66195, a synthetic DPP-IV inhibitor, in diet-induced obese mice and obese-diabetic ob/ob mice.
Lee EY; Kim YW; Oh H; Choi CS; Ahn JH; Lee BW; Kang ES; Cha BS; Lee HC
Metabolism; 2014 Jun; 63(6):793-9. PubMed ID: 24684824
[TBL] [Abstract][Full Text] [Related]
15. Pharmacological Modulation of Ghrelin to Induce Weight Loss: Successes and Challenges.
Schalla MA; Stengel A
Curr Diab Rep; 2019 Sep; 19(10):102. PubMed ID: 31506846
[TBL] [Abstract][Full Text] [Related]
16. Differential functional selectivity and downstream signaling bias of ghrelin receptor antagonists and inverse agonists.
Ramirez VT; van Oeffelen WEPA; Torres-Fuentes C; Chruścicka B; Druelle C; Golubeva AV; van de Wouw M; Dinan TG; Cryan JF; Schellekens H
FASEB J; 2019 Jan; 33(1):518-531. PubMed ID: 30020830
[TBL] [Abstract][Full Text] [Related]
17. Metabolic insights from a GHSR-A203E mutant mouse model.
Torz LJ; Osborne-Lawrence S; Rodriguez J; He Z; Cornejo MP; Mustafá ER; Jin C; Petersen N; Hedegaard MA; Nybo M; Damonte VM; Metzger NP; Mani BK; Williams KW; Raingo J; Perello M; Holst B; Zigman JM
Mol Metab; 2020 Sep; 39():101004. PubMed ID: 32339772
[TBL] [Abstract][Full Text] [Related]
18. Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet.
Lékó AH; Gregory-Flores A; Marchette RCN; Gomez JL; Vendruscolo JCM; Repunte-Canonigo V; Choung V; Deschaine SL; Whiting KE; Jackson SN; Cornejo MP; Perello M; You ZB; Eckhaus M; Rasineni K; Janda KD; Zorman B; Sumazin P; Koob GF; Michaelides M; Sanna PP; Vendruscolo LF; Leggio L
Commun Biol; 2024 May; 7(1):632. PubMed ID: 38796563
[TBL] [Abstract][Full Text] [Related]
19. Novel effects of the cannabinoid inverse agonist AM 251 on parameters related to metabolic syndrome in obese Zucker rats.
Merroun I; Sánchez-González C; Martínez R; López-Chaves C; Porres JM; Aranda P; Llopis J; Galisteo M; Zarzuelo A; Errami M; López-Jurado M
Metabolism; 2013 Nov; 62(11):1641-50. PubMed ID: 23932644
[TBL] [Abstract][Full Text] [Related]
20. Deletion of Growth Hormone Secretagogue Receptor in Kisspeptin Neurons in Female Mice Blocks Diet-Induced Obesity.
Conde K; Kulyk D; Vanschaik A; Daisey S; Rojas C; Wiersielis K; Yasrebi A; Degroat TJ; Sun Y; Roepke TA
Biomolecules; 2022 Sep; 12(10):. PubMed ID: 36291579
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]