98 related articles for article (PubMed ID: 28559181)
1. Deletion of one allele of Mthfd1 (methylenetetrahydrofolate dehydrogenase 1) impairs learning in mice.
Pjetri E; Zeisel SH
Behav Brain Res; 2017 Aug; 332():71-74. PubMed ID: 28559181
[TBL] [Abstract][Full Text] [Related]
2. Low Dietary Folate Interacts with MTHFD1 Synthetase Deficiency in Mice, a Model for the R653Q Variant, to Increase Incidence of Developmental Delays and Defects.
Christensen KE; Bahous RH; Hou W; Deng L; Malysheva OV; Arning E; Bottiglieri T; Caudill MA; Jerome-Majewska LA; Rozen R
J Nutr; 2018 Apr; 148(4):501-509. PubMed ID: 29659962
[TBL] [Abstract][Full Text] [Related]
3. Mild Choline Deficiency and MTHFD1 Synthetase Deficiency Interact to Increase Incidence of Developmental Delays and Defects in Mice.
Christensen KE; Malysheva OV; Carlin S; Matias F; MacFarlane AJ; Jacobs RL; Caudill MA; Rozen R
Nutrients; 2021 Dec; 14(1):. PubMed ID: 35011003
[TBL] [Abstract][Full Text] [Related]
4. Murine MTHFD1-synthetase deficiency, a model for the human MTHFD1 R653Q polymorphism, decreases growth of colorectal tumors.
Lévesque N; Christensen KE; Van Der Kraak L; Best AF; Deng L; Caldwell D; MacFarlane AJ; Beauchemin N; Rozen R
Mol Carcinog; 2017 Mar; 56(3):1030-1040. PubMed ID: 27597531
[TBL] [Abstract][Full Text] [Related]
5. Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice.
Beaudin AE; Perry CA; Stabler SP; Allen RH; Stover PJ
Am J Clin Nutr; 2012 Apr; 95(4):882-91. PubMed ID: 22378735
[TBL] [Abstract][Full Text] [Related]
6. Mthfd1 is a modifier of chemically induced intestinal carcinogenesis.
MacFarlane AJ; Perry CA; McEntee MF; Lin DM; Stover PJ
Carcinogenesis; 2011 Mar; 32(3):427-33. PubMed ID: 21156972
[TBL] [Abstract][Full Text] [Related]
7. Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development.
Christensen KE; Hou W; Bahous RH; Deng L; Malysheva OV; Arning E; Bottiglieri T; Caudill MA; Jerome-Majewska LA; Rozen R
Am J Clin Nutr; 2016 Nov; 104(5):1459-1469. PubMed ID: 27707701
[TBL] [Abstract][Full Text] [Related]
8. The MTHFD1 p.Arg653Gln variant alters enzyme function and increases risk for congenital heart defects.
Christensen KE; Rohlicek CV; Andelfinger GU; Michaud J; Bigras JL; Richter A; Mackenzie RE; Rozen R
Hum Mutat; 2009 Feb; 30(2):212-20. PubMed ID: 18767138
[TBL] [Abstract][Full Text] [Related]
9. A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development.
Christensen KE; Deng L; Leung KY; Arning E; Bottiglieri T; Malysheva OV; Caudill MA; Krupenko NI; Greene ND; Jerome-Majewska L; MacKenzie RE; Rozen R
Hum Mol Genet; 2013 Sep; 22(18):3705-19. PubMed ID: 23704330
[TBL] [Abstract][Full Text] [Related]
10. MTHFD1 gene: role in disease susceptibility and pharmacogenetics.
Krajinovic M
Pharmacogenomics; 2008 Jul; 9(7):829-32. PubMed ID: 18597647
[No Abstract] [Full Text] [Related]
11. Deletion of neural tube defect-associated gene Mthfd1l causes reduced cranial mesenchyme density.
Shin M; Vaughn A; Momb J; Appling DR
Birth Defects Res; 2019 Nov; 111(19):1520-1534. PubMed ID: 31518072
[TBL] [Abstract][Full Text] [Related]
12. MTHFD1 formyltetrahydrofolate synthetase deficiency, a model for the MTHFD1 R653Q variant, leads to congenital heart defects in mice.
Christensen KE; Deng L; Bahous RH; Jerome-Majewska LA; Rozen R
Birth Defects Res A Clin Mol Teratol; 2015 Dec; 103(12):1031-8. PubMed ID: 26408344
[TBL] [Abstract][Full Text] [Related]
13. A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: report of the Birth Defects Research Group.
Brody LC; Conley M; Cox C; Kirke PN; McKeever MP; Mills JL; Molloy AM; O'Leary VB; Parle-McDermott A; Scott JM; Swanson DA
Am J Hum Genet; 2002 Nov; 71(5):1207-15. PubMed ID: 12384833
[TBL] [Abstract][Full Text] [Related]
14. Triglyceride regulate ACE2 level through MTHFD1.
Ma X; Li X; Wan BO; Miao Z
J Biosci; 2021; 46(3):. PubMed ID: 34168100
[TBL] [Abstract][Full Text] [Related]
15. A polymorphism in the MTHFD1 gene increases a mother's risk of having an unexplained second trimester pregnancy loss.
Parle-McDermott A; Pangilinan F; Mills JL; Signore CC; Molloy AM; Cotter A; Conley M; Cox C; Kirke PN; Scott JM; Brody LC
Mol Hum Reprod; 2005 Jul; 11(7):477-80. PubMed ID: 16123074
[TBL] [Abstract][Full Text] [Related]
16. Association between MTHFD1 polymorphisms and neural tube defect susceptibility.
Meng J; Han L; Zhuang B
J Neurol Sci; 2015 Jan; 348(1-2):188-94. PubMed ID: 25524527
[TBL] [Abstract][Full Text] [Related]
17. Molecular genetic analysis of the gene encoding the trifunctional enzyme MTHFD (methylenetetrahydrofolate-dehydrogenase, methenyltetrahydrofolate-cyclohydrolase, formyltetrahydrofolate synthetase) in patients with neural tube defects.
Hol FA; van der Put NM; Geurds MP; Heil SG; Trijbels FJ; Hamel BC; Mariman EC; Blom HJ
Clin Genet; 1998 Feb; 53(2):119-25. PubMed ID: 9611072
[TBL] [Abstract][Full Text] [Related]
18. Deletion of Mthfd1l causes embryonic lethality and neural tube and craniofacial defects in mice.
Momb J; Lewandowski JP; Bryant JD; Fitch R; Surman DR; Vokes SA; Appling DR
Proc Natl Acad Sci U S A; 2013 Jan; 110(2):549-54. PubMed ID: 23267094
[TBL] [Abstract][Full Text] [Related]
19. Disruption of the mthfd1 gene reveals a monofunctional 10-formyltetrahydrofolate synthetase in mammalian mitochondria.
Christensen KE; Patel H; Kuzmanov U; Mejia NR; MacKenzie RE
J Biol Chem; 2005 Mar; 280(9):7597-602. PubMed ID: 15611115
[TBL] [Abstract][Full Text] [Related]
20. Common Variants in One-Carbon Metabolism Genes (
Pawlik P; Kurzawińska G; Ożarowski M; Wolski H; Piątek K; Słopień R; Sajdak S; Olbromski P; Seremak-Mrozikiewicz A
Int J Mol Sci; 2023 Aug; 24(16):. PubMed ID: 37628752
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]