415 related articles for article (PubMed ID: 28564594)
1. Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS.
Hall CE; Yao Z; Choi M; Tyzack GE; Serio A; Luisier R; Harley J; Preza E; Arber C; Crisp SJ; Watson PMD; Kullmann DM; Abramov AY; Wray S; Burley R; Loh SHY; Martins LM; Stevens MM; Luscombe NM; Sibley CR; Lakatos A; Ule J; Gandhi S; Patani R
Cell Rep; 2017 May; 19(9):1739-1749. PubMed ID: 28564594
[TBL] [Abstract][Full Text] [Related]
2. Modeling hallmark pathology using motor neurons derived from the family and sporadic amyotrophic lateral sclerosis patient-specific iPS cells.
Sun X; Song J; Huang H; Chen H; Qian K
Stem Cell Res Ther; 2018 Nov; 9(1):315. PubMed ID: 30442180
[TBL] [Abstract][Full Text] [Related]
3. Mechanistic Insights of Astrocyte-Mediated Hyperactive Autophagy and Loss of Motor Neuron Function in SOD1
Rajpurohit CS; Kumar V; Cheffer A; Oliveira D; Ulrich H; Okamoto OK; Zatz M; Ansari UA; Khanna VK; Pant AB
Mol Neurobiol; 2020 Oct; 57(10):4117-4133. PubMed ID: 32676988
[TBL] [Abstract][Full Text] [Related]
4. Coactivation of GSK3β and IGF-1 Attenuates Amyotrophic Lateral Sclerosis Nerve Fiber Cytopathies in SOD1 Mutant Patient-Derived Motor Neurons.
Ting HC; Yang HI; Harn HJ; Chiu IM; Su HL; Li X; Chen MF; Ho TJ; Liu CA; Tsai YJ; Chiou TW; Lin SZ; Chang CY
Cells; 2021 Oct; 10(10):. PubMed ID: 34685754
[TBL] [Abstract][Full Text] [Related]
5. Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis.
Tsioras K; Smith KC; Edassery SL; Garjani M; Li Y; Williams C; McKenna ED; Guo W; Wilen AP; Hark TJ; Marklund SL; Ostrow LW; Gilthorpe JD; Ichida JK; Kalb RG; Savas JN; Kiskinis E
Cell Rep; 2023 Oct; 42(10):113160. PubMed ID: 37776851
[TBL] [Abstract][Full Text] [Related]
6. Sporadic ALS Astrocytes Induce Neuronal Degeneration In Vivo.
Qian K; Huang H; Peterson A; Hu B; Maragakis NJ; Ming GL; Chen H; Zhang SC
Stem Cell Reports; 2017 Apr; 8(4):843-855. PubMed ID: 28366455
[TBL] [Abstract][Full Text] [Related]
7. Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS.
Luisier R; Tyzack GE; Hall CE; Mitchell JS; Devine H; Taha DM; Malik B; Meyer I; Greensmith L; Newcombe J; Ule J; Luscombe NM; Patani R
Nat Commun; 2018 May; 9(1):2010. PubMed ID: 29789581
[TBL] [Abstract][Full Text] [Related]
8. An autopsy report of a familial amyotrophic lateral sclerosis case carrying VCP Arg487His mutation with a unique TDP-43 proteinopathy.
Matsubara T; Izumi Y; Oda M; Takahashi M; Maruyama H; Miyamoto R; Watanabe C; Tachiyama Y; Morino H; Kawakami H; Saito Y; Murayama S
Neuropathology; 2021 Apr; 41(2):118-126. PubMed ID: 33415820
[TBL] [Abstract][Full Text] [Related]
9. Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis.
Smethurst P; Risse E; Tyzack GE; Mitchell JS; Taha DM; Chen YR; Newcombe J; Collinge J; Sidle K; Patani R
Brain; 2020 Feb; 143(2):430-440. PubMed ID: 32040555
[TBL] [Abstract][Full Text] [Related]
10. Altered astrocytic expression of TDP-43 does not influence motor neuron survival.
Haidet-Phillips AM; Gross SK; Williams T; Tuteja A; Sherman A; Ko M; Jeong YH; Wong PC; Maragakis NJ
Exp Neurol; 2013 Dec; 250():250-9. PubMed ID: 24120466
[TBL] [Abstract][Full Text] [Related]
11. Stress-Specific Spatiotemporal Responses of RNA-Binding Proteins in Human Stem-Cell-Derived Motor Neurons.
Harley J; Patani R
Int J Mol Sci; 2020 Nov; 21(21):. PubMed ID: 33172210
[TBL] [Abstract][Full Text] [Related]
12. 4-Aminopyridine Induced Activity Rescues Hypoexcitable Motor Neurons from Amyotrophic Lateral Sclerosis Patient-Derived Induced Pluripotent Stem Cells.
Naujock M; Stanslowsky N; Bufler S; Naumann M; Reinhardt P; Sterneckert J; Kefalakes E; Kassebaum C; Bursch F; Lojewski X; Storch A; Frickenhaus M; Boeckers TM; Putz S; Demestre M; Liebau S; Klingenstein M; Ludolph AC; Dengler R; Kim KS; Hermann A; Wegner F; Petri S
Stem Cells; 2016 Jun; 34(6):1563-75. PubMed ID: 26946488
[TBL] [Abstract][Full Text] [Related]
13. Mutant C9orf72 human iPSC-derived astrocytes cause non-cell autonomous motor neuron pathophysiology.
Zhao C; Devlin AC; Chouhan AK; Selvaraj BT; Stavrou M; Burr K; Brivio V; He X; Mehta AR; Story D; Shaw CE; Dando O; Hardingham GE; Miles GB; Chandran S
Glia; 2020 May; 68(5):1046-1064. PubMed ID: 31841614
[TBL] [Abstract][Full Text] [Related]
14. Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.
Serio A; Bilican B; Barmada SJ; Ando DM; Zhao C; Siller R; Burr K; Haghi G; Story D; Nishimura AL; Carrasco MA; Phatnani HP; Shum C; Wilmut I; Maniatis T; Shaw CE; Finkbeiner S; Chandran S
Proc Natl Acad Sci U S A; 2013 Mar; 110(12):4697-702. PubMed ID: 23401527
[TBL] [Abstract][Full Text] [Related]
15. C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Dafinca R; Scaber J; Ababneh N; Lalic T; Weir G; Christian H; Vowles J; Douglas AG; Fletcher-Jones A; Browne C; Nakanishi M; Turner MR; Wade-Martins R; Cowley SA; Talbot K
Stem Cells; 2016 Aug; 34(8):2063-78. PubMed ID: 27097283
[TBL] [Abstract][Full Text] [Related]
16. Role and Therapeutic Potential of Astrocytes in Amyotrophic Lateral Sclerosis.
Pehar M; Harlan BA; Killoy KM; Vargas MR
Curr Pharm Des; 2017; 23(33):5010-5021. PubMed ID: 28641533
[TBL] [Abstract][Full Text] [Related]
17. Slow development of ALS-like spinal cord pathology in mutant valosin-containing protein gene knock-in mice.
Yin HZ; Nalbandian A; Hsu CI; Li S; Llewellyn KJ; Mozaffar T; Kimonis VE; Weiss JH
Cell Death Dis; 2012 Aug; 3(8):e374. PubMed ID: 22898872
[TBL] [Abstract][Full Text] [Related]
18. Amyotrophic Lateral Sclerosis (ALS): Stressed by Dysfunctional Mitochondria-Endoplasmic Reticulum Contacts (MERCs).
Chen J; Bassot A; Giuliani F; Simmen T
Cells; 2021 Jul; 10(7):. PubMed ID: 34359958
[TBL] [Abstract][Full Text] [Related]
19. Astrocytes display cell autonomous and diverse early reactive states in familial amyotrophic lateral sclerosis.
Taha DM; Clarke BE; Hall CE; Tyzack GE; Ziff OJ; Greensmith L; Kalmar B; Ahmed M; Alam A; Thelin EP; Garcia NM; Helmy A; Sibley CR; Patani R
Brain; 2022 Apr; 145(2):481-489. PubMed ID: 35042241
[TBL] [Abstract][Full Text] [Related]
20. Motor neuron differentiation of iPSCs obtained from peripheral blood of a mutant TARDBP ALS patient.
Bossolasco P; Sassone F; Gumina V; Peverelli S; Garzo M; Silani V
Stem Cell Res; 2018 Jul; 30():61-68. PubMed ID: 29800782
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
