These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

293 related articles for article (PubMed ID: 28566325)

  • 1. Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing.
    Carroll B; Nelson G; Rabanal-Ruiz Y; Kucheryavenko O; Dunhill-Turner NA; Chesterman CC; Zahari Q; Zhang T; Conduit SE; Mitchell CA; Maddocks ODK; Lovat P; von Zglinicki T; Korolchuk VI
    J Cell Biol; 2017 Jul; 216(7):1949-1957. PubMed ID: 28566325
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
    Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
    Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hyperactivation of mammalian target of rapamycin complex 1 (mTORC1) promotes breast cancer progression through enhancing glucose starvation-induced autophagy and Akt signaling.
    Chen Y; Wei H; Liu F; Guan JL
    J Biol Chem; 2014 Jan; 289(2):1164-73. PubMed ID: 24275666
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.
    Peng M; Yin N; Li MO
    Cell; 2014 Sep; 159(1):122-133. PubMed ID: 25259925
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Re-evaluating the roles of proposed modulators of mammalian target of rapamycin complex 1 (mTORC1) signaling.
    Wang X; Fonseca BD; Tang H; Liu R; Elia A; Clemens MJ; Bommer UA; Proud CG
    J Biol Chem; 2008 Nov; 283(45):30482-92. PubMed ID: 18676370
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loss of TSC2 confers resistance to ceramide and nutrient deprivation.
    Guenther GG; Liu G; Ramirez MU; McMonigle RJ; Kim SM; McCracken AN; Joo Y; Ushach I; Nguyen NL; Edinger AL
    Oncogene; 2014 Apr; 33(14):1776-87. PubMed ID: 23604129
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lysosomal recruitment of TSC2 is a universal response to cellular stress.
    Demetriades C; Plescher M; Teleman AA
    Nat Commun; 2016 Feb; 7():10662. PubMed ID: 26868506
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TSC but not PTEN loss in starving cones of retinitis pigmentosa mice leads to an autophagy defect and mTORC1 dissociation from the lysosome.
    Venkatesh A; Ma S; Punzo C
    Cell Death Dis; 2016 Jun; 7(6):e2279. PubMed ID: 27362797
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Multiple amino acid sensing inputs to mTORC1.
    Shimobayashi M; Hall MN
    Cell Res; 2016 Jan; 26(1):7-20. PubMed ID: 26658722
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nutrient regulation of the mTOR complex 1 signaling pathway.
    Kim SG; Buel GR; Blenis J
    Mol Cells; 2013 Jun; 35(6):463-73. PubMed ID: 23694989
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Endoplasmic reticulum stress and cell death in mTORC1-overactive cells is induced by nelfinavir and enhanced by chloroquine.
    Johnson CE; Hunt DK; Wiltshire M; Herbert TP; Sampson JR; Errington RJ; Davies DM; Tee AR
    Mol Oncol; 2015 Mar; 9(3):675-88. PubMed ID: 25498902
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα).
    Dan HC; Ebbs A; Pasparakis M; Van Dyke T; Basseres DS; Baldwin AS
    J Biol Chem; 2014 Sep; 289(36):25227-40. PubMed ID: 24990947
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthetic lethality of combined glutaminase and Hsp90 inhibition in mTORC1-driven tumor cells.
    Li J; Csibi A; Yang S; Hoffman GR; Li C; Zhang E; Yu JJ; Blenis J
    Proc Natl Acad Sci U S A; 2015 Jan; 112(1):E21-9. PubMed ID: 25524627
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Amino Acids Regulate mTORC1 by an Obligate Two-step Mechanism.
    Dyachok J; Earnest S; Iturraran EN; Cobb MH; Ross EM
    J Biol Chem; 2016 Oct; 291(43):22414-22426. PubMed ID: 27587390
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MCRS1 binds and couples Rheb to amino acid-dependent mTORC1 activation.
    Fawal MA; Brandt M; Djouder N
    Dev Cell; 2015 Apr; 33(1):67-81. PubMed ID: 25816988
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Redox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway.
    Yoshida S; Hong S; Suzuki T; Nada S; Mannan AM; Wang J; Okada M; Guan KL; Inoki K
    J Biol Chem; 2011 Sep; 286(37):32651-60. PubMed ID: 21784859
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulated in DNA damage and development 1 (REDD1) promotes cell survival during serum deprivation by sustaining repression of signaling through the mechanistic target of rapamycin in complex 1 (mTORC1).
    Dennis MD; McGhee NK; Jefferson LS; Kimball SR
    Cell Signal; 2013 Dec; 25(12):2709-16. PubMed ID: 24018049
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Telomerase reverse transcriptase induces basal and amino acid starvation-induced autophagy through mTORC1.
    Ali M; Devkota S; Roh JI; Lee J; Lee HW
    Biochem Biophys Res Commun; 2016 Sep; 478(3):1198-204. PubMed ID: 27545609
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival.
    Efeyan A; Zoncu R; Chang S; Gumper I; Snitkin H; Wolfson RL; Kirak O; Sabatini DD; Sabatini DM
    Nature; 2013 Jan; 493(7434):679-83. PubMed ID: 23263183
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Current models of mammalian target of rapamycin complex 1 (mTORC1) activation by growth factors and amino acids.
    Zheng X; Liang Y; He Q; Yao R; Bao W; Bao L; Wang Y; Wang Z
    Int J Mol Sci; 2014 Nov; 15(11):20753-69. PubMed ID: 25402640
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.