BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 28569774)

  • 1. RGD-modified oncolytic adenovirus-harboring shPKM2 exhibits a potent cytotoxic effect in pancreatic cancer via autophagy inhibition and apoptosis promotion.
    Xu Y; Chu L; Yuan S; Yang Y; Yang Y; Xu B; Zhang K; Liu XY; Wang R; Fang L; Chen Z; Liang Z
    Cell Death Dis; 2017 Jun; 8(6):e2835. PubMed ID: 28569774
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Apoptin Inhibits Glycolysis and Regulates Autophagy by Targeting Pyruvate Kinase M2 (PKM2) in Lung Cancer A549 Cells.
    Song G; Shang C; Zhu Y; Xiu Z; Li Y; Yang X; Ge C; Han J; Jin N; Li Y; Li X; Fang J
    Curr Cancer Drug Targets; 2024; 24(4):411-424. PubMed ID: 36284386
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Potent antitumor effect of neurotensin receptor-targeted oncolytic adenovirus co-expressing decorin and Wnt antagonist in an orthotopic pancreatic tumor model.
    Na Y; Choi JW; Kasala D; Hong J; Oh E; Li Y; Jung SJ; Kim SW; Yun CO
    J Control Release; 2015 Dec; 220(Pt B):766-82. PubMed ID: 26471393
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pyruvate kinase type M2 contributes to the development of pancreatic ductal adenocarcinoma by regulating the production of metabolites and reactive oxygen species.
    Yokoyama M; Tanuma N; Shibuya R; Shiroki T; Abue M; Yamamoto K; Miura K; Yamaguchi K; Sato I; Tamai K; Satoh K
    Int J Oncol; 2018 Mar; 52(3):881-891. PubMed ID: 29393401
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel oncolytic adenovirus targeting Wnt signaling effectively inhibits cancer-stem like cell growth via metastasis, apoptosis and autophagy in HCC models.
    Zhang J; Lai W; Li Q; Yu Y; Jin J; Guo W; Zhou X; Liu X; Wang Y
    Biochem Biophys Res Commun; 2017 Sep; 491(2):469-477. PubMed ID: 28698142
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PKM2 gene regulates the behavior of pancreatic cancer cells via mitogen-activated protein kinase pathways.
    Feng J; Ma T; Ge Z; Lin J; Ding W; Chen H; Zhu W; Zhou S; Tan Y
    Mol Med Rep; 2015 Mar; 11(3):2111-7. PubMed ID: 25411978
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PKM2 Promotes Cell Survival and Invasion Under Metabolic Stress by Enhancing Warburg Effect in Pancreatic Ductal Adenocarcinoma.
    Li C; Zhao Z; Zhou Z; Liu R
    Dig Dis Sci; 2016 Mar; 61(3):767-73. PubMed ID: 26500118
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pyruvate kinase isoenzyme M2 is a therapeutic target of gemcitabine-resistant pancreatic cancer cells.
    Kim DJ; Park YS; Kang MG; You YM; Jung Y; Koo H; Kim JA; Kim MJ; Hong SM; Lee KB; Jang JJ; Park KC; Yeom YI
    Exp Cell Res; 2015 Aug; 336(1):119-29. PubMed ID: 26112218
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MIR210HG regulates glycolysis, cell proliferation, and metastasis of pancreatic cancer cells through miR-125b-5p/HK2/PKM2 axis.
    Yu T; Li G; Wang C; Gong G; Wang L; Li C; Chen Y; Wang X
    RNA Biol; 2021 Dec; 18(12):2513-2530. PubMed ID: 34110962
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway.
    Xu Q; Wu N; Li X; Guo C; Li C; Jiang B; Wang H; Shi D
    Cell Death Dis; 2019 Nov; 10(12):874. PubMed ID: 31745071
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Survivin silencing and TRAIL expression using oncolytic adenovirus increase anti-tumorigenic activity in gemcitabine-resistant pancreatic cancer cells.
    Han Z; Lee S; Je S; Eom CY; Choi HJ; Song JJ; Kim JH
    Apoptosis; 2016 Mar; 21(3):351-64. PubMed ID: 26677013
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The responsively decreased PKM2 facilitates the survival of pancreatic cancer cells in hypoglucose.
    Li X; Deng S; Liu M; Jin Y; Zhu S; Deng S; Chen J; He C; Qin Q; Wang C; Zhao G
    Cell Death Dis; 2018 Jan; 9(2):133. PubMed ID: 29374159
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of shRNA-Mediated Silencing of PKM2 Gene on Aerobic Glycolysis, Cell Migration, Cell Invasion, and Apoptosis in Colorectal Cancer Cells.
    Yan XL; Zhang XB; Ao R; Guan L
    J Cell Biochem; 2017 Dec; 118(12):4792-4803. PubMed ID: 28543190
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SAM68 promotes tumorigenesis in lung adenocarcinoma by regulating metabolic conversion via PKM alternative splicing.
    Zhu S; Chen W; Wang J; Qi L; Pan H; Feng Z; Tian D
    Theranostics; 2021; 11(7):3359-3375. PubMed ID: 33537092
    [No Abstract]   [Full Text] [Related]  

  • 15. A novel Golgi protein (GOLPH2)-regulated oncolytic adenovirus exhibits potent antitumor efficacy in hepatocellular carcinoma.
    Wang Y; Liu T; Huang P; Zhao H; Zhang R; Ma B; Chen K; Huang F; Zhou X; Cui C; Liu X
    Oncotarget; 2015 May; 6(15):13564-78. PubMed ID: 25980438
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PKM2 promotes metastasis by recruiting myeloid-derived suppressor cells and indicates poor prognosis for hepatocellular carcinoma.
    Liu WR; Tian MX; Yang LX; Lin YL; Jin L; Ding ZB; Shen YH; Peng YF; Gao DM; Zhou J; Qiu SJ; Dai Z; He R; Fan J; Shi YH
    Oncotarget; 2015 Jan; 6(2):846-61. PubMed ID: 25514599
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oncolytic Adenovirus Expressing ST13 Increases Antitumor Effect of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Against Pancreatic Ductal Adenocarcinoma.
    Zhang Y; Ye M; Huang F; Wang S; Wang H; Mou X; Wang Y
    Hum Gene Ther; 2020 Aug; 31(15-16):891-903. PubMed ID: 32475172
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Benserazide is a novel inhibitor targeting PKM2 for melanoma treatment.
    Zhou Y; Huang Z; Su J; Li J; Zhao S; Wu L; Zhang J; He Y; Zhang G; Tao J; Zhou J; Chen X; Peng C
    Int J Cancer; 2020 Jul; 147(1):139-151. PubMed ID: 31652354
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cutting off the fuel supply to calcium pumps in pancreatic cancer cells: role of pyruvate kinase-M2 (PKM2).
    James AD; Richardson DA; Oh IW; Sritangos P; Attard T; Barrett L; Bruce JIE
    Br J Cancer; 2020 Jan; 122(2):266-278. PubMed ID: 31819190
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HCCS1-armed, quadruple-regulated oncolytic adenovirus specific for liver cancer as a cancer targeting gene-viro-therapy strategy.
    Xu HN; Huang WD; Cai Y; Ding M; Gu JF; Wei N; Sun LY; Cao X; Li HG; Zhang KJ; Liu XR; Liu XY
    Mol Cancer; 2011 Nov; 10():133. PubMed ID: 22040050
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.